Haruharu Wonder Black Rice Hyaluronic Anti-wrinkle Serum for mature skin

How to apply

Questions and answers

What the research says

• Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.

  International Journal of Cosmetic Science, 2018

• Daily application of a cream containing niosomes loaded with purple glutinous rice extract in 20 human volunteers for 28 days resulted in a significant decrease in melanin index and skin roughness by -14.05% and -9.95%, and increases in skin hydration and elastic recovery by +48.73% and +35.98% compared to initial values.

  International Journal of Cosmetic Science, 2020

• Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

  International Journal of Molecular Sciences, 2026

• Camellia japonica oil activated the human COL1A2 promoter, induced type I procollagen synthesis, inhibited matrix metalloproteinase-1 activity, and reduced trans-epidermal water loss without inducing adverse reactions in human skin.

  Journal of Ethnopharmacology, 2007

• Tea seed oil makeup remover successfully removed foundation and eyeliner without causing skin irritation in 20 human volunteers, with the 60% formulation showing superior foundation removal compared to other formulations and an olive oil benchmark.

  Annales Pharmaceutiques Francaises, 2017

• Black rice extract treatment downregulated MMP-1 and MMP-3 expression, increased type I procollagen expression, and reduced reactive oxygen species production in ultraviolet-irradiated HaCaT and human dermal fibroblast skin cells.

  International Journal of Molecular Medicine, 2018

• Black rice hydrolyzed peptides induce a dose-dependent increase in hyaluronan synthase 2 gene expression and effectively increase hyaluronan production in HaCaT keratinocytes.

  Journal of Microbiology and Biotechnology, 2007

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects.

  Rejuvenation Research, 2015

• A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects.

  Journal of Ginseng Research, 2022

• A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline.

  Journal of Toxicology and Environmental Health. Part A, 2020

• Liquid crystalline emulsions formulated with camellia seed oil and four different surfactant combinations reduced transepidermal water loss and increased skin hydration without causing skin irritation, with the formulation containing Lecinol S-10 and Tween 80 demonstrating the best clinical results.

  Scientific Reports, 2023

Ingredients

Deionized Water, Glycerin, Lecithin, Caprylic Capric Triglyceride, Camellia Japonica Seed Oil, Hydrogenated Lecithin, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rice Extract, Phyllostachys Pubescens Shoot Bark Extract, Aspergillus Ferment, Sodium Hyaluronate, Panax Ginseng Root Extract, Cyclodextrin, Sclerotium Gum, C12-16 Alcohols, Palmitic Acid, Alteromonas Extract Ferment, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Beta-Glucan, 1,2-Hexanediol, Glycine Soja Soybean Sterols, Behenyl Alcohol, Jojoba Seed Oil, Glyceryl Stearate, Sodium Phytate, Tocopherol, Adenosine, Phenethyl Alcohol, Butylene Glycol, Alcohol, Lavandula Angustifolia Oil Lavender Oil

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.