# Good Molecules Overnight Exfoliating Treatment for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Good Molecules](https://lovi.care/skincare/es/brands/good-molecules)
Category: [Exfoliants](https://lovi.care/skincare/es/best/exfoliators)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few products fit it even better.

## Why this fit

- Offers excellent exfoliation for your wrinkles and fine lines due to glycolic acid and lactic acid, which promote skin renewal and smoothing texture for your normal skin.
- The presence of salicylic acid further aids in pore refinement, complementing the primary exfoliating agents.
- The formulation is safe for your normal skin, as it lacks harsh ingredients and carries no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/combination-skin): Superior
- [Sensitive skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/oily-acne-prone-skin): Superior

## Key ingredients

Aha Glycolic Acid, Bha Salicylic Acid, Lactic Acid, Glycerin, Sodium Hyaluronate

## What the research says

- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG. ([Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this affordable overnight treatment is widely praised for its ability to rapidly resurface skin, resulting in a smoother texture and a visible glow by morning. While highly effective for reducing acne and clogged pores, it is potent; users with sensitive skin often report stinging or "purging" and recommend starting slowly.

- Liked: Smoother texture (mostly mentioned)
- Liked: Unbeatable price (mostly mentioned)
- Liked: Radiant glow (often mentioned)
- Liked: Acne and pore reduction (sometimes noted)
- Disliked: Stinging sensation (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Scent and texture (rarely noted)
- Disliked: Skin purging (rarely noted)

## How to apply

- Use this exfoliant product in your PM routine once a week to start, increasing frequency only if your skin tolerates it well. Always apply SPF the next morning to protect your skin.
- Apply this exfoliant product after cleansing and toner, but before your moisturizer. This ensures the best absorption into your skin.
- Gently press 2-3 drops of the exfoliant product into your face, avoiding any rubbing. Let it absorb for a minute before moving to the next step.
- Apply this exfoliant product on completely dry skin to get the best results. This helps your normal skin accept the product smoothly.
- Avoid the sensitive eye area while using this exfoliant product. Do a patch test before your first use and avoid mixing it with strong acids.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### What makes Good Molecules Overnight Exfoliating Treatment a great fit for mature skin?

This product is a great fit because it offers excellent exfoliation for your wrinkles and fine lines using glycolic acid and lactic acid, which renew the skin and smooth its texture. Salicylic acid helps refine pores to complement the main exfoliants, and the formula is safe for your skin with no risk of irritation.

### Which ingredients make this exfoliant a good fit for mature skin?

Glycolic acid and lactic acid make this exfoliant a great fit by smoothing fine lines and helping with skin renewal. Salicylic acid also helps refine pores, while glycerin and sodium hyaluronate keep your skin feeling soft and comfortable.

### What does Glycolic Acid do for mature skin?

Glycolic acid helps mature skin by boosting collagen production and speeding up skin renewal to make it look smoother and firmer. It helps reduce wrinkles and improves skin texture over time, though it may occasionally cause mild irritation.
Sources: [Dermatologic Surgery, 1998](https://pubmed.ncbi.nlm.nih.gov/9793513/), [The Journal of Dermatology, 1998](https://pubmed.ncbi.nlm.nih.gov/9563274/)

### What does Bha do for mature skin?

BHA helps mature skin by smoothing out fine lines and increasing collagen to keep the face firm and elastic. Clinical studies show that regular use of ingredients like salicylic acid can improve skin thickness and reduce visible signs of aging.
Sources: [Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883290/), [Aesthetic Plastic Surgery, 2025](https://pubmed.ncbi.nlm.nih.gov/38926250/)

### Where does this exfoliant go in a skincare routine for mature skin?

Apply this treatment in the evening after cleansing and toning, and follow it with a moisturizer. Start using it just once a week, and if your skin responds well, you can carefully use it more often.

### Can I use this exfoliant with retinol, and in what order?

It is best not to use this exfoliant and retinol in the same routine, as combining strong treatments may cause dryness and irritation. Instead, alternate nights or use the exfoliant in your evening routine and your retinol at a different time.

### How often should I use this exfoliant?

Start using this exfoliant treatment once a week in the evening, and if your skin tolerates it well and shows good results, you can carefully use it more often. This approach helps smooth your texture and soften wrinkles while keeping your skin calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32356917/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/)

### Can this exfoliant clog pores, cause breakouts or purging for mature skin?

This exfoliant is unlikely to cause breakouts or clog pores, and skin purging is low for mature skin. It helps refine pores and smooth texture safely without harsh ingredients.

### Is this exfoliant fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denatured, ethanol, and alcohol).

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €169.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/es/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.00 at Amazon
- Moisturizer: [Shiseido Benefiance Wrinkle Smoothing Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-cream-enriched/for/mature-skin) — Superior fit — €57.95 at Amazon

## Where to buy

- Amazon.de: €20.99 (https://www.amazon.de/dp/B08TMDRF1L?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycolic Acid, Sodium Citrate, Propanediol, Glycerin, 1,2-Hexanediol, Lactic Acid, Salicylic Acid, Tocopherol, Sorbitan Oleate, Sodium Hyaluronate, Ethylhexylglycerin, Hydroxyethylcellulose, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Xanthan Gum, Butylene Glycol, Polysorbate 80, Citrus Aurantium Dulcis Oil, Citrus Aurantifolia Oil, Lemon Oil Fruit, Grapefruit Peel Oil, Bergamot Oil Fruit, Disodium Edta, Alcohol Denatured, Phenoxyethanol, Chlorphenesin, Peg-60 Hydrogenated Castor Oil, Ethanol, Alcohol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- France: https://lovi.care/skincare/fr/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/overnight-exfoliating-treatment/for/mature-skin