# Genabelle PDRN Vita Toning Ampoule for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Genabelle](https://lovi.care/skincare/es/brands/genabelle)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for oily skin.

## Why this fit

- Highly suitable for your oily skin, niacinamide and sodium ascorbyl phosphate work synergistically to control sebum production and brighten your complexion, addressing your concerns about oily shine.
- The formula also contains rosemary oil, which offers antioxidant benefits and can help soothe inflammation, further complementing your skin's needs.
- The product is safe for your skin, with no harsh ingredients or irritants identified.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Pdrn Polydeoxyribonucleotide, Niacinamide, Vitamin Capsule, Sodium Dna, Tocopheryl Acetate

## What the research says

- Combined ascorbyl palmitate and sodium ascorbyl phosphate treatment significantly reduced facial sebum secretions in healthy female volunteers compared to a placebo control over 90 days. ([Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- The tetrapeptide PKEK exerts skin whitening effects by reducing UVB-stimulated mRNA expression of pigmentation-inducing mediators like POMC and tyrosinase, and significantly fades facial pigment spots when combined with sodium ascorbyl phosphate. ([Experimental Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22142309/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Polydeoxyribonucleotide treatment induces mitochondrial biogenesis while reducing melanin biosynthesis, tyrosinase activity, MITF expression, elastase activity, and MMP-1 gene expression in cultured skin cells. ([Applied Biochemistry and Biotechnology, 2020](https://pubmed.ncbi.nlm.nih.gov/31811642/))
- Polydeoxyribonucleotide derived from Hibiscus sabdariffa callus at 5 μg/mL promoted wound healing and upregulated related genes and proteins in human keratinocytes. ([Biochemical and Biophysical Research Communications, 2024](https://pubmed.ncbi.nlm.nih.gov/38996695/))
- Polydeoxyribonucleotide isolated from Saussurea involucrata promoted cell proliferation, migration, and collagen synthesis while suppressing MMP1 expression in human skin cells. ([Cellular and Molecular Biology, 2025](https://pubmed.ncbi.nlm.nih.gov/41351364/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))

## What reviewers say

Users consistently praise this ampoule for its lightweight, non-sticky hydration that leaves skin feeling plump and looking radiant, making it suitable for dull or dehydrated skin. While many appreciate the soothing effects of PDRN and the brightening vitamin capsules, some users note that results are gradual rather than immediate and that the product can be pricey without a discount.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Gentle and soothing (often mentioned)
- Disliked: Expensive price point (often mentioned)
- Liked: Brightening glow (sometimes noted)
- Disliked: Subtle results (sometimes noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Unwanted fragrance (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Genabelle PDRN Vita Toning Ampoule a great fit for oily skin?

Genabelle PDRN Vita Toning Ampoule is a great fit because niacinamide and sodium ascorbyl phosphate work together to control oily shine and brighten your face. Rosemary oil also helps calm inflammation, and the formula is safe without harsh irritants.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide and sodium ascorbyl phosphate make this a great fit because they work together to control oily shine and brighten your complexion. Rosemary oil is also included to help soothe inflammation and provide antioxidant benefits.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does PDRN do for oily skin?

PDRN helps calm and repair oily skin by supporting skin cell growth and collagen production. This ingredient is unlikely to clog pores while working to improve the overall texture and healing of your skin.

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for oily skin?

This treatment serum goes in your evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol, but apply this serum first and let it absorb before putting on your retinol. It is a great fit for oily skin, as its ingredients work to control shine and brighten your complexion without harsh irritants.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### How often should I use this serum?

Genabelle PDRN Vita Toning Ampoule is used in the evening routine. The formula is safe for oily skin and helps control shine and brighten the complexion.
Sources: [Drug Research, 2017](https://pubmed.ncbi.nlm.nih.gov/27756097/), [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

Genabelle PDRN Vita Toning Ampoule is unlikely to clog pores or cause breakouts on oily skin, as its tocopheryl acetate has a safe profile with non-comedogenic potential. The formula is free of heavy, pore-blocking ingredients and harsh irritants.
Sources: [Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €169.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €29.76 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €17.49 at Amazon

## Where to buy

- Amazon.de: €27.35 (https://www.amazon.de/dp/B0DL8PSG8Z?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Niacinamide, Polyglycerin-3, Methylpropanediol, 1,2-Hexanediol, Glycereth-26, Glycerin, Mannitol, Sodium Dna, Polyglyceryl-10 Laurate, Microcrystalline Cellulose, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ammonium Acryloyldimethyltaurate Vp Copolymer, Arginine, Zea Mays Starch, Ethylhexylglycerin, Allantoin, Caprylyl Glycol, Mica, Adenosine, Rosmarinus Officinalis Oil Leaf Rosemary Oil Leaf, Biosaccharide Gum-1, Iron Oxides Ci 77492, Calcium Pantothenate, Maltodextrin, Sodium Octenylsuccinate Starch, Sodium Ascorbyl Phosphate, Pyridoxine Hcl, Tocopheryl Acetate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- France: https://lovi.care/skincare/fr/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/genabelle/pdrn-vita-toning-ampoule/for/oily-skin