Eucerin Q10 Anti-Wrinkle + Pro-Retinol Night Cream for dry skin

Ubiquinone
Pro-Retinol
Retinyl Palmitate
Shea Butter
Macadamia Ternifolia Seed Oil
Average
- HighDry Skin Fit
- AverageEffectiveness
- HighSafety
Works for dry skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your dry skin due to the presence of glycerin and shea butter, which provide hydration and emollient actions, respectively, though it lacks specialized ingredients to directly target flakiness.
- The inclusion of retinyl palmitate and ubiquinone offers anti-aging effects and general skin support, complementing the moisturizing properties for your dry skin.
- The product is safe for your dry skin, as it contains no harsh or prohibited ingredients that could cause irritation.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.4Overall rating based on 10.0k+ reviewsBased on a very large amount of data, this night cream is highly recommended for sensitive and dry skin, offering significant hydration and a gentle approach to reducing fine lines. While most users appreciate its moisturizing properties and improvement in skin texture, some find the scent unpleasant and the formula too rich for oily skin or prefer more potent anti-aging effects.
Highlights
Gentle on sensitive skin Mostly Mentioned
- “No irritation or redness even on my reactive skin”
- “Perfect for sensitive skin that can't handle strong retinol”
- “Does not sting or burn like other anti-aging creams”
Deeply moisturizing Often Mentioned
- “Wake up with incredibly soft and plump skin”
- “Rich texture that hydrates dry patches overnight”
- “Leaves my face feeling nourished but not greasy”
Good absorption Sometimes Noted
- “Absorbs quickly despite being a thick cream”
- “Sinks in well, doesn't sit on top of skin”
- “Non-greasy finish that doesn't stain pillowcases”
Great value Sometimes Noted
- “Beats expensive luxury creams for a fraction of the price”
- “Affordable enough to use generously on neck and chest”
- “High quality ingredients for a drugstore price”
Improves skin texture Sometimes Noted
- “Skin feels smoother and firmer in the morning”
- “Helps with crepey texture on my neck”
- “Softens fine lines around the eyes and mouth”
Unpleasant scent Sometimes Noted
- “Has a weird, sour chemical smell”
- “Smells like old ingredients or 'science'”
- “Unscented but has a funky natural odor”
Mild/slow results Rarely Noted
- “Didn't see dramatic changes in deep wrinkles”
- “Good moisturizer but weak anti-aging effects”
- “Takes months to see a visible difference”
Too thick/rich Rarely Noted
- “Feels a bit heavy and waxy on the skin”
- “Caused some congestion on my oily T-zone”
- “Too thick for summer or humid weather”
Yellow discoloration Rarely Noted
- “The cream has a yellow tint that can look odd”
- “Stained my white pillowcase slightly”
- “Color looks off, like it oxidized”
Sources: lovi.care, iherb.com, amazon.com, walmart.com, cvs.com, kroger.com, and more
Questions and answers
How well does Eucerin Q10 Anti-Wrinkle + Pro-Retinol Night Cream work for dry skin?
This cream works okay for dry skin, providing moderate moisture and anti-aging benefits, though it may not do enough for flakiness. A product of this type needs highly effective, soothing ingredients and hydrating agents like hyaluronic acid and glycerin to give dry skin optimal hydration, nourishment, and skin barrier support without irritation.
Which ingredients make this cream a good fit for dry skin?
Glycerin and shea butter make this cream a good fit for dry skin by providing essential hydration and softening benefits. To be an even better fit, a product for dry skin needs effective moisturizing ingredients like hyaluronic acid and glycerin to ensure deep hydration, along with soothing agents that directly target flakiness without any risk of irritation.
What does Coenzyme Q10 do for dry skin?
Coenzyme Q10 helps dry skin by boosting cellular energy and providing antioxidant protection that defends against daily stress. It also improves moisture levels to leave skin feeling soft and smooth.
BioFactors, 2015International Journal of Pharmaceutics, 2010
What does Pro-Retinol do for dry skin?
Pro-retinol helps reduce dryness while improving skin texture and tone. This type of ingredient works well when paired with rich moisturizers or plant oils that add extra hydration and soothe rough areas.
Journal of Cosmetic Dermatology, 2013Journal of Drugs in Dermatology, 2022
Where does this cream go in a skincare routine for dry skin?
This moisturizing treatment goes in your evening routine after cleansing and before your regular moisturizer. Applying this product at night helps prevent any extra sensitivity to the sun from the active ingredients, while glycerin and shea butter provide hydration and softness to dry skin.
Can I use this cream with vitamin C, and in what order?
You can use this cream with vitamin C by applying vitamin C first and following with this moisturizer. This order helps protect dry skin while delivering hydration, and the product is unlikely to cause irritation.
How often should I use this cream?
This cream is used in the evening as part of your routine for dry skin. Daily application is generally well tolerated and helps improve skin moisture and softness.
Can this cream clog pores, cause breakouts or purging for dry skin?
This cream is unlikely to clog pores or cause breakouts for dry skin, as its safety profile shows it contains no harsh ingredients that typically trigger irritation. Because it includes retinyl palmitate, it may cause mild purging as your skin adjusts, but reviews show very few complaints about this.
Journal of Cosmetic Dermatology, 2013Colloids and Surfaces. B, Biointerfaces, 2011
Can I use this cream around the eyes or on my body?
You can use this cream on your body and around the eyes, as it is safe and well-tolerated by dry skin. However, because the skin around the eyes and on certain body areas is particularly thin, a product of this type needs rich moisturizers and gentle smoothing ingredients to effectively protect and soften these sensitive zones without causing irritation.
Surgical and Radiologic Anatomy, 2002Journal of Cosmetic Dermatology, 2013
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and stearyl alcohol are fatty alcohols, which soften the skin.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A vitamin A palmitate and antioxidant-containing oil-based moisturizer improved fine lines, wrinkles, pigmentation, tone, texture, dryness, firmness, and clarity across various body sites compared to a no-treatment group over 12 weeks.
Journal of Cosmetic Dermatology, 2013Retinyl palmitate-loaded non-ionic lamellar liquid crystalline systems provided a significant reduction of orbicular wrinkles in human volunteers compared to systems without retinyl palmitate.
Colloids and Surfaces. B, Biointerfaces, 2011Topical treatment with coenzyme Q10 formulas replenishes Q10 levels in the skin surface and deeper epidermis, augments cellular energy metabolism, and reduces free radicals while increasing antioxidant capacity in stressed skin.
BioFactors, 2015Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism.
BioFactors, 2008Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects.
Colloids and Surfaces. B, Biointerfaces, 2023Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects.
Antioxidants, 2021Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question.
The Journal of Clinical and Aesthetic Dermatology, 2021A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women.
The British Journal of Dermatology, 2010A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation.
International Journal of Cosmetic Science, 2024A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025
Why other moisturizers fit dry skin better
Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles.
The Journal of Clinical and Aesthetic Dermatology, 2012A 10% urea plus NMF moisturizer significantly improved total stratum corneum water content and the water gradient down to a depth of 15 μm compared to its vehicle in subjects with dry skin.
Skin Research and Technology, 2022
Ingredients
Water, Glycerin, Ethylhexyl Cocoate, Cetyl Alcohol, Hydrogenated Coco-Glycerides, Stearyl Alcohol, Butylene Glycol, Caprylic Capric Triglyceride, Butyrospermum Parkii Butter Shea Butter, Glyceryl Stearate Citrate, Macadamia Ternifolia Seed Oil, Octyldodecanol, Ubiquinone, Retinyl Palmitate, Tocopherol, 1,2-Hexanediol, Dehydroacetic Acid, Carbomer, Sodium Hydroxide, Trisodium Edta
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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