🇪🇸Spain

E45 Cream for sensitive skin

Average

  • AverageNormal Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for sensitive skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate moisturizing for your normal skin due to the presence of glycerin, which hydrates effectively, but it does not directly address your concerns of redness and irritation.
  • While the formula is generally safe and free from harsh ingredients for your sensitive skin, it lacks specific active components to provide significant benefits for your primary skin issues.
  • The safety profile is excellent, with no risks of irritation for your sensitive skin due to the absence of prohibited or harsh ingredients.

How to apply

  • Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
  • Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
  • Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
  • You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
  • Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .

People Say

★4.7Overall rating based on 500+ reviews

While widely celebrated for being gentle and fragrance-free, some users with oily or acne-prone skin find it too heavy or comedogenic for facial use.

Highlights

  • Soothes dry skin Mostly Mentioned
    • “stopped the itching”
    • “healed dry patches”
  • Gentle and fragrance-free Often Mentioned
    • “no stinging”
    • “great for sensitive skin”
    • “perfect for babies”
    • “zero irritation”
  • Improves skin texture Often Mentioned
    • “skin feels soft”
    • “smooths rough elbows”
    • “leaves a protective film”
    • “softens calluses”
  • Excellent value Sometimes Noted
    • “huge tub lasts ages”
    • “affordable price”
    • “cheap but effective”
    • “great budget skincare”
  • Versatile multi-purpose Sometimes Noted
    • “good for sunburn”
    • “used after shaving”
    • “great hand cream”
    • “works on cracked heels”
  • Greasy or sticky Sometimes Noted
    • “feels slimy”
    • “takes ages to absorb”
    • “leaves a greasy film”
    • “makes hands slippery”
  • Causes breakouts Rarely Noted
    • “clogged my pores”
    • “gave me whiteheads”
    • “too heavy for face”
    • “caused acne flare-up”
  • Lanolin sensitivity Rarely Noted
    • “caused allergic reaction”
    • “made rash worse”
    • “redness and stinging”
    • “irritated my skin”
  • Packaging issues Rarely Noted
    • “pump stopped working”
    • “tub is unhygienic”
    • “messy to use”
    • “lid broke easily”

Sources: lovi.care, boots.com, superdrug.com, influenster.com, ocado.com, reddit.com, and more

Questions and answers

How well does E45 Cream work for sensitive skin?

E45 Cream works moderately well for sensitive skin, providing basic hydration without causing irritation, though it does not target redness or calm irritated areas. This type of skin needs soothing ingredients like fermented Centella Asiatica, Cica Ceramide, and nourishing oils that calm redness and repair the skin barrier without causing any irritation.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for sensitive skin?

Glycerin helps hydrate your sensitive skin safely because the formula has an excellent safety profile without harsh ingredients, though it lacks specific components for redness and irritation. To fit this skin better, a moisturizer needs soothing ingredients that calm redness and irritation, such as fermented Centella Asiatica, Cica Ceramide, and nourishing oils.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does White Soft Paraffin do for sensitive skin?

White soft paraffin helps protect sensitive skin by locking in moisture and repairing the outer skin barrier. It is unlikely to cause irritation or allergic reactions, making it safe and soothing for delicate skin types.

Journal of the American Academy of Dermatology, 1992Journal of the American Academy of Dermatology, 2024

What does Light Liquid Paraffin do for sensitive skin?

Light Liquid Paraffin helps calm sensitive skin by sealing in moisture and protecting the outer barrier. Refined mineral oils stay on the surface without penetrating deeply, making them very safe and unlikely to cause irritation.

Journal of the European Academy of Dermatology and Venereology, 2019American Journal of Clinical Dermatology, 2003

Where does this cream go in a skincare routine for sensitive skin?

This cream goes at the end of your evening routine as a moisturizer, and it is safe from harsh ingredients that might upset your sensitive skin. However, because it lacks specific active components to calm redness and irritation, a product for this skin needs soothing ingredients and targeted actives to address those primary concerns.

The Journal of Dermatological Treatment, 2022

Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying it after your retinol treatment to help keep your skin feeling soft and comfortable. This type of moisturizer is generally safe for sensitive skin, but to properly care for redness and irritation, it needs soothing active ingredients and barrier-restoring components like ceramides.

How often should I use this cream?

You can use this cream daily to help keep your skin hydrated, as its gentle formula is safe and unlikely to cause irritation.

Health Science Reports, 2021Dermatology, 2003

Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to cause breakouts for sensitive skin, as reviewers report this issue at a low rate and the formula avoids harsh ingredients.

Can I use this cream around the eyes or on my body?

This cream is generally safe to use on both the body and the face, including around the eyes, because it lacks harsh ingredients and has a very safe formula. However, this skin type needs a product that includes soothing active ingredients to calm redness and irritation.

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017
  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020
  • Topical treatment with skin-identical lipids in a petrolatum-rich cream base showed no superiority over pure petrolatum in promoting normalization of barrier recovery and inflammation in detergent- and tape-stripped-perturbed human skin over 14 days.

    Acta Dermato-venereologica, 2000
  • Topically applied extra virgin olive oil and petrolatum both significantly improved skin barrier function and microtopographic features in 54 healthy adult volunteers, with petrolatum exerting stronger occlusive effects and extra virgin olive oil uniquely promoting epidermal renewal.

    Journal of Clinical Medicine, 2025
  • Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers.

    International Journal of Pharmaceutics, 2019
  • Daily bathing with an emulsified lanolin and mineral oil bath additive significantly reduced dry skin severity on the lower legs of patients compared to usual bath soap over 17 days.

    Cutis, 1981
  • Sunscreen formulations containing ethoxylated lanolin as an additional film former resulted in lower and constant physical-mechanical parameters and a higher and better reproducible SPF compared to the formulation without it.

    International Journal of Pharmaceutics, 2021
  • Nanoemulsion-based lanolin derivatives increased skin hydration and oiliness without changing cutaneous pH values and proved non-toxic by causing no skin irritation.

    Molecules, 2016
  • A novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid showed similar tolerance and efficacy compared with clindamycin 1% and benzoyl peroxide 5% gel in subjects with acne vulgaris.

    Journal of Drugs in Dermatology, 2013
  • Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris.

    Journal of Cosmetic Dermatology, 2021
  • Topical 20% citric acid lotion increases viable epidermal thickness and dermal glycosaminoglycan content in sun-damaged skin compared to vehicle alone.

    Dermatologic Surgery, 1997

Why other moisturizers fit sensitive skin better

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024
  • Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

    American Journal of Clinical Dermatology, 2002
  • A dexpanthenol-containing cream accelerated skin barrier repair, increased stratum corneum hydration, reduced skin roughness, and decreased skin redness compared to vehicle and untreated controls in sodium lauryl sulphate-irritated skin.

    The Journal of Dermatological Treatment, 2002

Ingredients

Water, Glycerin, Paraffinum Liquidum, Glyceryl Stearate, Sodium Cetearyl Sulfate, Carbomer, Methylparaben, Propylparaben, Sodium Hydroxide

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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Prices checked 6 Nov 2026

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

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