# Dr. Althea 345 Relief Cream for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Dr. Althea](https://lovi.care/skincare/es/brands/dr-althea)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your dry and sensitive skin as hyaluronic acid and ceramide NP provide excellent hydration and barrier support, effectively addressing dryness and flakiness. Glycerin and panthenol further enhance moisture retention and soothe irritation, complementing the primary ingredients for comprehensive care.
- The formulation includes numerous botanical extracts and adenosine, which offer additional soothing and anti-aging benefits, supporting overall skin health without compromising your sensitivity.
- The safety profile is excellent, with no harsh ingredients and a focus on soothing components, ensuring a gentle experience for your dry and sensitive skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/oily-acne-prone-skin): Superior

## Key ingredients

Niacinamide, Centella Asiatica, Hyaluronic Acid, Ceramide, Oenothera Biennis Oil

## What the research says

- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Electrospun poly (vinyl butyral-co-vinyl alcohol-co-vinyl acetate) patches loaded with evening primrose oil applied to the forearm of volunteers for 6 hours increased skin moisture, with pore size, shape, and fiber diameter influencing oil transport. ([Biomaterials Advances, 2022](https://pubmed.ncbi.nlm.nih.gov/35929319/))
- A topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil, and sodium pyruvate led to clinical improvement after a month in diverse hyperkeratotic skin conditions except pityriasis lichenoides. ([Medicina Cutanea Ibero-latino-americana, 1986](https://pubmed.ncbi.nlm.nih.gov/3528709/))
- Topical application of linseed, evening primrose, and olive oil emulsions accelerated wound closure in rats with excision wounds compared to untreated controls, though via different mechanisms. ([Drug Delivery and Translational Research, 2019](https://pubmed.ncbi.nlm.nih.gov/29667150/))

## What reviewers say

Based on a very large amount of data, this gel-cream is highly regarded by users with oily and acne-prone skin for its lightweight, fast-absorbing texture that effectively soothes redness and strengthens the skin barrier without causing pore congestion. Some users with dry skin find it insufficiently moisturizing, and a few report occasional breakouts or pilling when layered with other products.

- Liked: Hydrating for Oily Skin (often mentioned)
- Liked: Lightweight & Fast Absorbing (often mentioned)
- Liked: Soothing & Calming (often mentioned)
- Liked: Improves Skin Texture (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Not moisturizing enough (sometimes noted)
- Disliked: Pilling issues (rarely noted)
- Disliked: Scent/Irritation (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Dr. Althea 345 Relief Cream a great fit for dry sensitive skin?

Dr. Althea 345 Relief Cream is a great fit because hyaluronic acid and ceramide NP provide deep hydration and support the skin barrier to calm dryness and flakiness. Glycerin and panthenol help keep moisture locked in while soothing irritation, and the gentle formula avoids harsh ingredients to keep sensitive skin comfortable.
Sources: [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Which ingredients make this cream a good fit for dry sensitive skin?

This cream is a great fit because hyaluronic acid and ceramide NP provide deep hydration and barrier support to stop dryness and flakiness. Glycerin and panthenol also help lock in moisture while soothing irritation gently.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Centella Asiatica do for dry sensitive skin?

Centella asiatica helps calm dry sensitive skin by improving moisture, reducing water loss, and soothing irritation. Using this ingredient helps repair the skin barrier and keeps the skin feeling soft and comfortable.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in your evening routine as a treatment step, applied after your toner and before your moisturizer. Using a gentle, hydrating routine with ingredients like hyaluronic acid, ceramides, and panthenol helps keep dry and sensitive skin calm and soft.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol, and applying it first helps calm your skin and build tolerance against dryness and irritation. This cream is a great fit because its hyaluronic acid and ceramide provide deep hydration and barrier support, while glycerin and panthenol soothe sensitivity.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/), [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your morning and evening routine to keep dry and sensitive skin hydrated. Daily application helps lock in moisture, soothe irritation, and support your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to clog pores or cause breakouts for dry sensitive skin, as it has a very gentle and safe formula focused on soothing and hydration. However, some reviewers do report moderate breakouts, which can happen with any rich moisturizing treatment depending on individual skin responses.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its gentle formula with hyaluronic acid and ceramide provides deep hydration and barrier support. Studies show that similar hydrating and soothing creams are well-tolerated and help reduce fine lines in the delicate eye area while keeping sensitive skin calm and smooth.
Sources: [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/), [International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — €11.50 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/es/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — €59.99 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/dry-sensitive-skin) — Superior fit — €13.67 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.de: €9.99 (https://www.amazon.de/dp/B0G643D8ZG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €18.75 (https://www.lookfantastic.es/p/dr.-althea-345-relief-cream-50ml/17729496/)
- Notino: €22.00 (https://www.notino.es/dr-althea/345-relief-cream-crema-calmante-y-nutritiva-para-pieles-sensibles/p-16315837/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Propanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Caprylic Capric Triglyceride, Niacinamide, Panthenol, Polyglycerin-3, Polyglyceryl-10 Stearate, Hydrogenated Poly C6-14 Olefin, Hydrogenated Polydecene, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Melia Azadirachta Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Oenothera Biennis Flower Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Calendula Officinalis Flower Extract, Agave Tequilana Leaf Extract, Sargassum Fulvellum Extract, Corallina Officinalis Extract, Lavandula Angustifolia Flower Extract, Centella Asiatica Leaf Extract, Opuntia Ficus-Indica Stem Extract, Gardenia Florida Fruit Extract, Perilla Ocymoides Leaf Extract, Hibiscus Sabdariffa Flower Extract, Hyaluronic Acid, Hydrogenated Lecithin, Empetrum Nigrum Fruit Juice, Dicaprylyl Carbonate, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polymethylsilsesquioxane, Dipropylene Glycol, Butylene Glycol, C12-20 Alkyl Glucoside, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Polyquaternium-51, Tromethamine, Fructooligosaccharides, Adenosine, Beta-Glucan, Glycine Soja Soybean Sterols, Peg-40 Castor Oil, Hydrolyzed Hyaluronic Acid, Resveratrol, Tocopherol, Ceramide Np, Oligopeptide-1, Phenoxyethanol, Potassium Sorbate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/dry-sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/dr-althea/345-relief-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/dr-althea/345-relief-cream/for/dry-sensitive-skin