# Derma E Pure Biome Balancing Cleanser for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Derma E](https://lovi.care/skincare/es/brands/derma-e)
Category: [Cleansers](https://lovi.care/skincare/es/best/cleansers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few cleansers fit it even better.

## Why this fit

- Highly suitable for your dry skin, this cleanser effectively addresses dryness and flakiness with humectants like glycerin and panthenol, complemented by barrier-repairing aloe barbadensis leaf juice.
- Decyl glucoside provides excellent cleansing without stripping moisture, while Centella Asiatica Cell Culture Meristem Cell Culture and chamomile extract offer soothing benefits.
- The formula is safe for your dry skin, containing no harsh or irritating ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Cell Culture Meristem Cell Culture, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Camellia Sinensis Leaf Extract, Glycerin, Allantoin

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

This sulfate-free gel cleanser is highly praised by users with sensitive and reactive skin for its ability to clean effectively without causing dryness or irritation. While it is celebrated for calming redness and maintaining skin balance, some users remain skeptical about the actual impact of its prebiotic/postbiotic ingredients given the short contact time during washing.

- Liked: Gentle on skin (often mentioned)
- Liked: Non-stripping formula (often mentioned)
- Liked: Calms redness/irritation (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Disliked: Potential for sensitivity (rarely noted)
- Disliked: Questionable biome claims (rarely noted)
- Disliked: Scent formula changes (rarely noted)

## How to apply

- Use this cleanser AM and PM every day to keep your skin clean. Start using it daily right away since your skin is not sensitive.
- Apply this cleanser as the very first step in your morning routine and right after your pre-cleanser in the evening. Follow with your toner and moisturizer afterwards.
- Gently massage a small amount of cleanser onto your face using soft circular motions. Rinse thoroughly with lukewarm water and pat dry with a clean towel.
- Apply this cleanser on slightly damp skin for a comfortable and refreshing wash. This helps maintain your skin's natural moisture while cleansing away dirt.
- Avoid getting the cleanser directly into your eyes to prevent any irritation. Do a simple patch test before your first use to ensure your skin likes it.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### What makes DERMA E Pure Biome Balancing Cleanser a great fit for dry skin?

This cleanser is a great fit because it uses glycerin and panthenol to tackle dryness and flakiness, while aloe juice helps repair your skin barrier. Its gentle cleanser washes away dirt without stripping moisture, and calming extracts help keep your dry skin feeling soft and comfortable.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this cleanser a good fit for dry skin?

Glycerin, panthenol, and aloe barbadensis leaf juice make this cleanser a great fit for dry skin by drawing in moisture, boosting hydration, and supporting the skin barrier. Decyl glucoside cleanses gently without stripping away natural oils, while centella asiatica and chamomile help calm the skin.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Centella Asiatica do for dry skin?

Centella asiatica helps dry skin by boosting moisture levels and keeping water locked in to make the skin feel softer and smoother. It also calms redness and supports the natural barrier to prevent everyday irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Lactobacillus Ferment do for dry skin?

Lactobacillus Ferment helps dry skin by locking in moisture and making the skin feel soft and smooth. Studies show that using probiotic ferment ingredients significantly increases skin hydration and strengthens the skin barrier to keep dryness away.
Sources: [Scientific Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37803101/), [Medical Archives, 2022](https://pubmed.ncbi.nlm.nih.gov/35774045/)

### Where does this cleanser go in a skincare routine for dry skin?

This cleanser fits into both your morning and evening routine, used as the main cleanser in the morning and following a makeup remover at night. Using a mild cleanser like this helps improve dryness and supports your skin barrier without stripping away essential moisture.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser with retinol by applying the cleanser first, followed by your retinol treatment, as part of a routine that helps keep dry skin clean without stripping away moisture. This cleanser uses gentle cleansing agents alongside glycerin and panthenol to support your skin barrier while you use active ingredients like retinol.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this cleanser?

You can use this cleanser twice a day in your morning and evening routines. A gentle daily cleansing routine helps improve clinical scores and visual dryness without stripping your skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cleanser clog pores, cause breakouts or purging for dry skin?

This cleanser is a great fit for dry skin and is unlikely to cause breakouts or clog pores because it uses gentle cleansers that clean without stripping away essential moisture. It features soothing ingredients and hydrating components that help keep dry skin calm and comfortable.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this cleanser around the eyes or on my body?

Yes, you can use this cleanser around your eyes and on your body, as its gentle ingredients wash away dirt without stripping moisture. Its hydrating and soothing formula is generally well tolerated on thinner areas like the eyelids and across larger body regions.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Stearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — €8.85 at Amazon
- [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/es/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — €19.75 at Amazon
- [ETUDE Soonjung pH 6.5 Whip Cleanser](https://lovi.care/skincare/es/p/etude/soonjung-ph-6-5-whip-cleanser/for/dry-skin) — Superior fit — €20.43 at Amazon

## Pairs well with

- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [d'Alba First Spray Serum](https://lovi.care/skincare/es/p/d-alba/first-spray-serum/for/dry-skin) — Superior fit — €16.99 at Amazon
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/es/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — €12.98 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Decyl Glucoside, Stearyl Alcohol, Panthenol, Centella Asiatica Cell Culture Meristem Cell Culture, Inulin, Ganoderma Lucidum Extract Mushroom Extract, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Xanthophyll Lutein, Cucumis Sativus Fruit Extract, Panax Quinquefolius Root Extract Panax Ginseng Root Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Ombopogon Schoenanthus Extract, Allantoin, Aloe Barbadensis Leaf Juice, Pinus Pinaster Bark Extract, Glyceryl Stearate Citrate, Xanthan Gum, Sucrose, Tapioca Starch, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- France: https://lovi.care/skincare/fr/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/pure-biome-balancing-cleanser/for/dry-skin