# Derma E Anti-Wrinkle Cleanser for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: High · Safety: Concerning.

Page: https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Derma E](https://lovi.care/skincare/es/brands/derma-e)
Category: [Cleansers](https://lovi.care/skincare/es/best/cleansers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other cleansers fit it better.

## Why this fit

- Offers moderate exfoliation for your dry and flaky skin due to Glycolic Acid and Retinyl Palmitate Vitamin A, which promote skin renewal, but lacks sufficient hydrating ingredients to fully address dryness.
- The cleansing agents, Sodium Methyl Cocoyl Taurate and Cocamidopropyl Hydroxysultaine, are effective for pore decongestion, but the overall formula could benefit from more emollient ingredients to better suit dry skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/oily-acne-prone-skin): Average

## Key ingredients

Vitamin A, Glycolic Acid, Bakuchiol, Retinol, Carica Papaya Fruit Extract

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))

## Why other cleansers fit dry sensitive skin better

- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- Phytosphingosine increased filaggrin metabolism and skin hydration in human skin by stimulating filaggrin biosynthesis and degradation leading to natural moisturizing factor formation. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28936777/))
- A cream containing panthenol, prebiotics, and probiotic lysate improved facial sensitive skin symptoms and skin barrier function in 110 participants over 28 days. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38186043/))

## What reviewers say

This cleanser is widely praised for its effective makeup removal and ability to leave skin feeling clean and smooth without excessive dryness. While it is a favorite for many seeking a budget-friendly, cruelty-free option for daily use, individuals with sensitive skin or specific skin conditions should be mindful of its exfoliating ingredients, which can occasionally lead to redness or irritation. This summary is based on a very large amount of data and should definitely be taken into account.

- Liked: Effective makeup removal (mostly mentioned)
- Liked: Gentle daily use (often mentioned)
- Liked: Non-stripping formula (often mentioned)
- Liked: Good value (sometimes noted)
- Disliked: Potential irritation (sometimes noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Scent concerns (rarely noted)

## How to apply

- Use your cleanser AM and PM every day to keep your face fresh. Start slowly once a day if your dry skin feels sensitive at first.
- Apply your cleanser first thing in your routine before any toner or moisturizer. Follow the usual steps for your AM or PM daily routine.
- Gently massage the cleanser onto your face using soft circular motions. Avoid harsh rubbing to protect your dry skin.
- Apply the cleanser to slightly damp skin to help it clean gently without stripping moisture. This method is very safe for sensitive and dry skin types.
- Rinse thoroughly with lukewarm water and avoid the delicate eye area. Always do a patch test before using the product for the first time.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### How well does Derma E Anti-Wrinkle Cleanser work for dry sensitive skin?

Derma E Anti-Wrinkle Cleanser offers moderate exfoliation for your dry and flaky skin with glycolic acid and vitamin A, but lacks sufficient hydrating ingredients to fully address dryness. A cleanser for this skin type needs hydrating and barrier-repairing ingredients like ceramides and hyaluronic acid to maintain moisture and protect the skin.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this cleanser a good fit for dry sensitive skin?

Glycolic Acid and Retinyl Palmitate Vitamin A make this cleanser a fit by offering moderate exfoliation and renewal for dry and flaky skin. However, since this is an average fit, a cleanser for this skin needs plenty of hydrating and barrier-repairing ingredients like ceramides and hyaluronic acid to lock in moisture and protect the skin.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What does Vitamin A do for dry sensitive skin?

Vitamin A helps build collagen and thickens skin layers, but it may cause dryness and stinging in sensitive skin. Products of this type for dry sensitive skin need soothing ingredients and gentle delivery systems to keep skin calm and comfortable.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What does Glycolic Acid do for dry sensitive skin?

Glycolic acid can be too harsh for dry sensitive skin and may cause irritation, so this skin type needs gentle calming ingredients and deeply nourishing moisturizers to keep the skin barrier safe and smooth.
Sources: [Acta Dermato-venereologica, 1995](https://pubmed.ncbi.nlm.nih.gov/8651024/), [The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/)

### Where does this cleanser go in a skincare routine for dry sensitive skin?

This cleanser goes in your morning and evening routine, though a product of this type needs more moisturizing and softening ingredients to properly care for dry skin.

### Can I use this cleanser with vitamin C, and in what order?

You can use this cleanser with vitamin C, but it is best to apply vitamin C in the morning and reserve this exfoliating cleanser for your evening routine to help prevent irritation on dry sensitive skin. A product of this type needs extra hydrating and soothing ingredients to keep dry skin soft and comfortable.

### How often should I use this cleanser?

You can use this cleanser daily, but because it provides moderate exfoliation, start by using it just once a week to see how your skin responds. If your dry sensitive skin tolerates it well without extra dryness or irritation, you may gradually use it more often. A cleanser for this skin needs more hydrating and soothing ingredients to keep it soft and comfortable.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cleanser clog pores, cause breakouts or purging for dry sensitive skin?

This cleanser is unlikely to clog pores, and it helps smooth flaky dry skin with exfoliating ingredients like glycolic acid and vitamin A. However, because it lacks rich moisturizing ingredients, a cleanser for dry skin needs extra soothing and hydrating agents to keep the skin soft and comfortable.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Can I use this cleanser around the eyes or on my body?

You should avoid using this cleanser around your eyes, as the active ingredients like glycolic acid and retinol may cause irritation on delicate skin. For your body, this type of cleanser needs extra moisturizing ingredients and gentle softening oils to properly care for and comfort dry skin.

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/es/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-sensitive-skin) — Superior fit — €19.75 at Amazon
- [ETUDE Soonjung pH 6.5 Whip Cleanser](https://lovi.care/skincare/es/p/etude/soonjung-ph-6-5-whip-cleanser/for/dry-sensitive-skin) — Superior fit — €20.43 at Amazon

## Pairs well with

- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €16.99 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/es/p/missha/ultra-hyalon-cleansing-cream/for/dry-sensitive-skin) — Superior fit — €10.97 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Sodium Methyl Cocoyl Taurate, Cocamidopropyl Hydroxysultaine, Cocamidopropyl Betaine, Glyceryl Laurate, Glycolic Acid, Bakuchiol, Retinyl Palmitate Vitamin A, Carica Papaya Fruit Extract, Equisetum Arvense Extract, Macrocystis Pyrifera Extract Kelp Extract, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Oils
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/anti-wrinkle-cleanser/for/dry-sensitive-skin