# Clinique Dramatically Different Moisturizing Gel for mature skin

**Lovi Fit: Low fit for mature skin.**
Normal Skin Fit: Superior · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Clinique](https://lovi.care/skincare/es/brands/clinique)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A weak match for mature skin; the moisturizers alongside fit it better.

## Why this fit

- Offers moderate hydration for your normal skin, as glycerin and sodium hyaluronate provide excellent humectant action, but it lacks specialized ingredients to effectively target your wrinkles and fine lines.
- Dimethicone offers emollient benefits, contributing to overall skin comfort and smoothness.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin): Low (this page)
- [Dry sensitive skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Sodium Hyaluronate, Dimethicone, Laminaria Digitata Extract, Cucumis Sativus Fruit Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- A skincare regimen containing Macrocystis pyrifera ferment consisting of a cleansing foam, a serum, and a moisturizer decreases the visible effects of inflammation and aging while promoting healing and improving patient satisfaction. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38922798/))
- Macrocystis pyrifera ferment-containing creams decrease visible inflammation and signs of aging while enhancing barrier resilience and recovery. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38041526/))
- Aqueous extracts from Macrocystis pyrifera and Durvillaea antarctica exhibited antiviral activity against acyclovir-sensitive and acyclovir-resistant HSV-1 and HSV-2, and topical formulations significantly reduced the severity and duration of HSV-1 skin lesions in an animal model compared to mock treatment and acyclovir. ([Frontiers in Microbiology, 2020](https://pubmed.ncbi.nlm.nih.gov/33013743/))
- Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38336313/))
- Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream. ([Endocrine, Metabolic & Immune Disorders Drug Targets, 2021](https://pubmed.ncbi.nlm.nih.gov/32628604/))
- Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats. ([The International Journal of Lower Extremity Wounds, 2024](https://pubmed.ncbi.nlm.nih.gov/34791922/))

## Why other moisturizers fit mature skin better

- Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement. ([Nanomaterials, 2024](https://pubmed.ncbi.nlm.nih.gov/38668218/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Topical cream containing saffron extract and avocado oil improved wrinkle grading, reduced nasolabial fold area and volume, and increased skin elasticity in twenty healthy volunteers over 12 weeks without allergic reactions. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31957954/))

## What reviewers say

This oil-free gel is a highly-rated favorite for oily and combination skin, appreciated for its very lightweight, fast-absorbing texture that hydrates without feeling heavy or clogging pores. It also performs well as a base for makeup. However, a significant number of users with dry skin or in colder climates find it not moisturizing enough, and a small number report breakouts or reactions.

- Liked: Lightweight absorption (mostly mentioned)
- Liked: Controls oil (often mentioned)
- Liked: Good under makeup (often mentioned)
- Disliked: Not moisturizing enough (often mentioned)
- Liked: Non-irritating formula (sometimes noted)
- Disliked: Pricey for basics (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### Why is Clinique Dramatically Different Moisturizing Gel a weak match for mature skin?

This moisturizer is a weak match for mature skin because, while it provides moderate hydration with glycerin and sodium hyaluronate and makes skin smooth with dimethicone, it lacks specialized ingredients to effectively target wrinkles and fine lines. A moisturizer for mature skin needs potent anti-aging ingredients, peptides, antioxidants, and a rich blend of hydrators to nourish the skin and improve the appearance of lines.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizer a poor fit for mature skin?

This moisturizer is a weak match for mature skin because it lacks specialized ingredients to effectively target wrinkles and fine lines, offering only moderate hydration. To properly care for mature skin, a product of this type needs potent anti-aging ingredients, peptides, antioxidants, and a rich blend of softeners and moisture-binding components.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this moisturizer go in a skincare routine for mature skin?

This moisturizer goes in the morning and evening routine after cleansing and any treatment serums. To better care for mature skin, a product of this type needs specialized ingredients that target wrinkles and fine lines.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/), [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40327583/)

### Can I use this moisturizer with retinol, and in what order?

You can use this moisturizer with retinol to help keep your skin comfortable and smooth, applying the moisturizer either before or after your retinol treatment depending on how sensitive your skin is. Using a gentle moisturizer alongside retinol may help reduce dryness and irritation while supporting your skin barrier.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this moisturizer?

You can use this moisturizer twice a day, in the morning and evening, to keep your skin feeling soft and comfortable. While it provides good hydration, mature skin needs a moisturizer with specialized ingredients that target wrinkles and fine lines.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this moisturizer clog pores, cause breakouts or purging for mature skin?

This moisturizer is unlikely to cause breakouts for mature skin, as reviewer complaints about breakouts are low. However, because it is a weak match for mature skin, a product of this type needs richer nourishing ingredients and targeted anti-aging actives like peptides or retinoids to properly care for wrinkles and dryness.

### Can I use this moisturizer around the eyes or on my body?

This moisturizer is generally fine to use on the body and around the eyes because the skin on the body and eyelids is thin and can benefit from lightweight hydration. However, for mature skin, a product of this type needs specialized firming ingredients and richer moisture to effectively target wrinkles and fine lines.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this moisturizer fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/es/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — €59.99 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/mature-skin) — Superior fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/mature-skin) — High fit — €11.50 at Amazon

## Routine for mature skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/es/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.00 at Amazon
- Moisturizer: [Shiseido Benefiance Wrinkle Smoothing Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-cream-enriched/for/mature-skin) — Superior fit — €57.95 at Amazon
- SPF: [Bioré UV Perfect Milk SPF 50+ PA++++](https://lovi.care/skincare/es/p/biore/uv-face-milk-spf50-pa/for/mature-skin) — Superior fit — €25.88 at Amazon

### PM

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/es/p/pyunkang-yul/deep-cleansing-oil/for/mature-skin) — Superior fit — €18.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.80 at Amazon
- Cleansing Toner: [Inkey List PHA Toner](https://lovi.care/skincare/es/p/the-inkey-list/pha-toner/for/mature-skin) — Superior fit — €10.00 at Amazon
- Serum or Treatment: [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- Moisturizer: [Shiseido Benefiance Wrinkle Smoothing Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-cream-enriched/for/mature-skin) — Superior fit — €57.95 at Amazon

### Weekly

- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/es/p/pyunkang-yul/deep-cleansing-oil/for/mature-skin) — Superior fit — €18.99 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.80 at Amazon
- Enzyme Powder: [Fancl Facial Washing Powder](https://lovi.care/skincare/es/p/fancl/facial-washing-powder/for/mature-skin) — Superior fit — €19.99 at Amazon
- Nourishing Mask: [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/es/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — €12.46 at Amazon
- Serum or Treatment: [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- Moisturizer: [Shiseido Benefiance Wrinkle Smoothing Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-cream-enriched/for/mature-skin) — Superior fit — €57.95 at Amazon

## Where to buy

- Amazon.de: €24.46 (https://www.amazon.de/dp/B003JRI3OG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €45.71 (https://www.lookfantastic.es/p/clinique-dramatically-different-moisturising-lotion-200ml/13221005/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Dimethicone, Isododecane, Butylene Glycol, Bis-Peg-18 Methyl Ether Dimethyl Silane, Glycerin, Laminaria Digitata Extract, Polygonum Cuspidatum Root Extract, Saccharomyces Lysate Extract, Cucumis Sativus Fruit Extract, Hordeum Vulgare Extract Extrait Dorge Extract, Helianthus Annuus Seedcake Sunflower Seedcake, Caffeine, Trehalose, Sodium Hyaluronate, Tocopheryl Acetate, Polysilicone-11, Silica, Propylene Glycol Dicaprate, Oleth-10, Lactobacillus Ferment, Laureth-23, Laureth-4, Ammonium Acryloyldimethyltaurate Vp Copolymer, Carbomer, Caprylyl Glycol, Hexylene Glycol, Tromethamine, Disodium Edta, Phenoxyethanol, Potassium Sorbate, Yellow 5 Ci 19140, Red 4 Ci 14700, Ci 15985
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- France: https://lovi.care/skincare/fr/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/clinique/dramatically-different-moisturizing-gel/for/mature-skin