# BY ECOM Heartleaf Ampoule for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: BY ECOM
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for oily skin.

## Why this fit

- Highly suitable for your oily skin, this formula features Enantia Chlorantha Bark Extract and Oleanolic Acid to effectively control sebum production and reduce oily shine.
- The inclusion of Houttuynia Cordata Extract and Willow Bark Extract further supports your acne-prone skin by decongesting pores and minimizing blemishes.
- The product is safe for your skin, with Centella Asiatica Extract and Anthemis Nobilis Flower Extract providing soothing benefits and no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Heartleaf Extract, Sodium Hyaluronate, Glycerin, Centella Asiatica Extract, Curcuma Longa Root Extract

## What the research says

- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))

## What reviewers say

Users with oily and acne-prone skin frequently report that this ampoule effectively soothes inflammation and provides a cooling sensation. A moderate number of users also find it hydrating and notice some pore refining effects. A significant minority of reviewers mention a sticky finish and a strong alcohol scent, with some experiencing irritation or breakouts. Results for pore shrinking are mixed.

- Liked: Hydrating texture (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Aesthetic packaging (sometimes noted)
- Liked: Pore refining (sometimes noted)
- Disliked: Alcohol scent (sometimes noted)
- Disliked: Pore claims weak (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Caused irritation (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes BY ECOM Heartleaf Ampoule a great fit for oily skin?

BY ECOM Heartleaf Ampoule is a great fit for oily skin because it features ingredients that help control sebum production and reduce oily shine while keeping pores clear. It also includes soothing plant extracts that help calm the skin and are unlikely to cause irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Which ingredients make this serum a good fit for oily skin?

This serum is a great fit for oily skin because it features Enantia Chlorantha Bark Extract and Oleanolic Acid to control sebum and reduce oily shine. Houttuynia Cordata Extract and Willow Bark Extract help clear pores and reduce blemishes, while Centella Asiatica Extract and Anthemis Nobilis Flower Extract safely soothe the skin.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Heartleaf Extract do for oily skin?

Heartleaf Extract helps calm oily skin by lowering inflammation and fighting bacteria that can clog pores. It may also protect skin from daily stress and irritation while keeping it clear and balanced.
Sources: [Bioscience, Biotechnology, and Biochemistry, 2016](https://pubmed.ncbi.nlm.nih.gov/27023331/), [Applied Biochemistry and Biotechnology, 2023](https://pubmed.ncbi.nlm.nih.gov/36495375/)

### What does Hyaluronic Acid do for oily skin?

Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/)

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in your evening routine after cleansing and toning, and before moisturizing. It helps manage extra oil and clear pores while keeping your skin calm.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it after your cleanser and before your moisturizer. It is unlikely to cause irritation when combined with a retinoid, as soothing ingredients help keep the skin calm.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It is a great fit for your oily skin because it helps control shine and keeps pores clear.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This ampoule is unlikely to clog pores or cause breakouts for oily skin, as it features willow bark extract to help keep pores clear and ingredients that control shiny oil. Centella asiatica extract is also included to calm the skin and keep irritation low.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for oily skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €169.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €29.76 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Houttuynia Cordata Extract, Methylpropanediol, Butylene Glycol, Glycerin, 2-Hexanediol, Cyclohexasiloxane, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Lemon Fruit Extract, Monarda Didyma Leaf Extract, Citrus Aurantium Dulcis Fruit Extract, Anthemis Nobilis Flower Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Pteris Multifida Extract, Cynara Scolymus Leaf Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Chestnut Shell Extract, Piper Methysticum Stem Extract Root Leaf, Panax Ginseng Extract Berry, Corallina Officinalis Extract, Willow Bark Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Paeonia Albiflora Root Extract, Cnidium Officinale Root Extract, Pueraria Thunbergiana Root Extract, Portulaca Oleracea Extract, Enantia Chlorantha Bark Extract, Persea Gratissima Fruit Extract Avocado Fruit Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Water-Soluble Collagen, Aloe Barbadensis Leaf Juice, Sh-Polypeptide-19, Ammonium Acryloyldimethyltaurate Vp Copolymer, Xanthan Gum, Water, Carbomer, Fructooligosaccharides, Beta-Glucan, Disodium Edta, Tromethamine, Polyquaternium-51, Hydrolyzed Hyaluronic Acid, Alcohol, Lecithin, Pistacia Lentiscus Gum, Maltodextrin, Sodium Phosphate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Oleanolic Acid, Ethylhexylglycerin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/by-ecom/heartleaf-ampoule/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/by-ecom/heartleaf-ampoule/for/oily-skin
- France: https://lovi.care/skincare/fr/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/by-ecom/heartleaf-ampoule/for/oily-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/by-ecom/heartleaf-ampoule/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/by-ecom/heartleaf-ampoule/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/by-ecom/heartleaf-ampoule/for/oily-skin