# Bioderma Sensibio Defensive for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Bioderma](https://lovi.care/skincare/es/brands/bioderma)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your oily skin due to the presence of glycerin and xylitol, which hydrate and enhance barrier resilience, but it does not directly address concerns about oily shine.
- Fructooligosaccharides provide humectant action suitable for oily skin, though stronger ingredients for oil control would improve its overall effectiveness.
- The product is safe for your oily skin, with Tocopherol and Glycyrrhetinic Acid offering soothing benefits and no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Glycyrrhetinic Acid, Laminaria Ochroleuca Extract, Tocopherol, Fructooligosaccharides

## What the research says

- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- A dermo-cosmetic formula containing 2% enoxolone significantly reduced erythema at 24 hours and pain at 30 minutes following non-ablative fractional laser treatment in 10 healthy subjects compared to a moisturizer control. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38622995/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of a cream containing 2.5% glycyrrhetinic acid significantly reduced thigh fat thickness and circumference compared to placebo in healthy women. ([Steroids, 2005](https://pubmed.ncbi.nlm.nih.gov/15894038/))
- Topical application of B-Resorcinol and Glycyrrhetinic acid effectively lightens hand solar lentigines after 4 weeks of treatment both with and without prior fractional laser photothermolysis, showing no statistical difference between the two approaches. ([Journal of Cosmetic Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27325103/))
- Glycyrrhetinic acid inhibited skin 11 beta-hydroxysteroid dehydrogenase and potentiated the vasoconstrictor action of hydrocortisone. ([Lancet, 1990](https://pubmed.ncbi.nlm.nih.gov/1970371/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## Why other moisturizers fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Bioderma Sensibio Defensive work for oily skin?

This cream works moderately well for oily skin by providing basic hydration, but it does not directly target oily shine. To work better for this skin type, a product needs lightweight textures, oil-controlling ingredients, and peptides that hydrate without heavy oils or clogged pores.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### Which ingredients make this cream a good fit for oily skin?

Glycerin, xylitol, and fructooligosaccharides make this cream a good fit for oily skin by providing hydration, while tocopherol and glycyrrhetinic acid offer soothing benefits with a low risk of irritation. However, because it does not directly address oily shine, a product for oily skin also needs lightweight textures, oil-controlling ingredients, and ingredients that support the skin barrier without heavy oils.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### What does Glycerin do for oily skin?

Glycerin helps keep oily skin hydrated without feeling heavy and supports the skin barrier. Because this product is a weak fit for your skin, an ideal product of this type needs lightweight hydrators and ingredients that balance oil while protecting the skin.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### What does Glycyrrhetinic Acid do for oily skin?

Glycyrrhetinic Acid helps calm red and irritated oily skin while soothing everyday flare-ups. It also helps balance surface oil so your face feels fresh and comfortable.

### Where does this cream go in a skincare routine for oily skin?

This moisturizing treatment goes in the evening routine after your cleansing toner and before your moisturizer. It hydrates oily skin and calms it safely, but an oily skin routine also needs oil-controlling ingredients.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the retinol first and following it with this moisturizer to help soothe your skin and keep it comfortable. This product of this type works well for oily skin when it includes oil-controlling ingredients to manage shine.

### How often should I use this cream?

This cream works well when applied as part of your morning and evening routine to keep your skin soft and hydrated. Daily application helps maintain moisture and calmness, as supported by studies on these ingredients.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### Can this cream clog pores, cause breakouts or purging for oily skin?

This cream is unlikely to clog pores or cause breakouts on oily skin, as it has a safe profile with soothing ingredients like tocopherol and glycyrrhetinic acid. However, because it does not control oily shine, this skin type needs extra oil-balancing ingredients for the best results.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because its ingredients have a very safe profile, though it is only a moderate fit for oily skin. To care for oily skin, a product of this type needs oil-control ingredients that manage shine.
Sources: [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-skin) — High fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/oily-skin) — High fit — €11.50 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/es/p/belif/the-true-cream-aqua-bomb/for/oily-skin) — High fit — €35.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — €36.00 at Amazon
- SPF: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/oily-skin) — Superior fit — €16.99 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Cetearyl Isononanoate, Cetearyl Alcohol, Glyceryl Stearate, Peg-100 Stearate, Mannitol, Xylitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Tocopherol, Glycyrrhetinic Acid, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Caprylic Capric Triglyceride, 1,2-Hexanediol, Caprylyl Glycol, Pentylene Glycol, Xanthan Gum, Disodium Edta, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/sensibio-defensive/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/sensibio-defensive/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/bioderma/sensibio-defensive/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/sensibio-defensive/for/oily-skin
- France: https://lovi.care/skincare/fr/p/bioderma/sensibio-defensive/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/bioderma/sensibio-defensive/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioderma/sensibio-defensive/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/bioderma/sensibio-defensive/for/oily-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/bioderma/sensibio-defensive/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/bioderma/sensibio-defensive/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/bioderma/sensibio-defensive/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioderma/sensibio-defensive/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/sensibio-defensive/for/oily-skin