# Bioderma Hydrabio Serum for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Bioderma](https://lovi.care/skincare/es/brands/bioderma)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your combination skin due to glycerin and sodium hyaluronate, which hydrate and plump without exacerbating oily shine.
- Niacinamide and Pyrus Malus Fruit Extract provide general skincare benefits that support your skin's hydration needs.
- The formula is safe for your combination skin, as it lacks harsh ingredients and has no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/oily-acne-prone-skin): High

## Key ingredients

Aquagenium Patent, Sodium Hyaluronate, Niacinamide, Glycerin, Laminaria Ochroleuca Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Dermocosmetic creams containing 6%, 12%, and 15% of standardized wild apple fruit ultrasonic extract increased skin hydration proportionally to extract concentration after 28 days of application on healthy volunteers without altering transepidermal water loss or skin pH. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35048513/))
- A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation. ([International Journal of Cosmetic Science, 2019](https://pubmed.ncbi.nlm.nih.gov/31050807/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum for its lightweight, gel-like texture that delivers deep hydration without leaving a sticky residue, making it ideal for dehydrated and sensitive skin. While most find it plumps and smooths the complexion effectively, those with extremely dry skin often note it works best when layered under a richer moisturizer rather than as a standalone solution.

- Liked: Lightweight & fast-absorbing (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Excellent makeup base (sometimes noted)
- Liked: Sensitive skin friendly (sometimes noted)
- Disliked: Fragrance presence (sometimes noted)
- Disliked: Price vs. size (sometimes noted)
- Disliked: Availability issues (rarely noted)
- Disliked: Not enough for dry skin (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Bioderma Hydrabio Serum work for combination skin?

Bioderma Hydrabio Serum works moderately well for combination skin because it hydrates and plumps with glycerin and sodium hyaluronate without adding oily shine, though other products fit this skin better. A moisturizing treatment for combination skin needs effective brightening and hydrating ingredients that reduce oily shine while avoiding irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Glycerin and sodium hyaluronate make this serum a good fit by hydrating and plumping your combination skin without exacerbating oily shine, while niacinamide and wild apple fruit extract support those hydration needs. To fit combination skin even better, a moisturizing treatment needs effective brightening ingredients, soothing agents, and antioxidants that target hydration while reducing oily shine without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35048513/)

### What does Aquagenium Patent do for combination skin?

Aquagenium Patent helps combination skin stay comfortably soft by encouraging natural moisture where dry areas need it most. It uses the skin's own signals to rebalance hydration, leaving your face feeling smooth without getting oily.

### What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and before moisturizing, following Lovi routines that place treatments at night for simplicity and extra safety around sun exposure. Combination skin works best with treatments that provide lightweight hydration and balance oil without causing shine.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your skin, followed by your retinol product once it absorbs. This approach helps reduce potential dryness and irritation while supporting your skin barrier during treatment.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this serum?

This treatment is used in the evening as part of your routine. Daily application helps keep your skin hydrated and smooth without making it feel oily.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

Bioderma Hydrabio Serum is unlikely to clog pores, cause breakouts, or lead to purging on combination skin, as its formula lacks harsh ingredients and carries no risk of irritation. However, because it only offers moderate hydration, combination skin often benefits more from lightweight, balancing formulas with niacinamide and ceramides to keep both dry and oily zones comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum around the eyes or on my body?

You can use this serum around the eyes and on the body because its gentle formula is safe and unlikely to irritate thin or sensitive areas. This type of product needs hydrating ingredients like glycerin and hyaluronic acid to effectively care for delicate skin.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €11.50 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/es/p/belif/the-true-cream-aqua-bomb/for/combination-skin) — High fit — €35.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

- Amazon.de: €26.69 (https://www.amazon.de/dp/B00E6BM38G?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €34.80 (https://www.notino.es/bioderma/hydrabio-hyalu-serum-serum-concentrado-contra-los-signos-del-envejecimiento-de-la-piel-para-pieles-deshidratadas/p-16204161/)
- Lookfantastic: €39.10 (https://www.lookfantastic.es/p/bioderma-hydrabio-hyalu-face-serum-for-dry-dehydrated-skin-with-hyaluronic-acid-and-niacinamide-30ml/14939661/)
Prices checked 14 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Xylitol, Sodium Polyacrylate, Mannitol, Rhamnose, Fructooligosaccharides, Laminaria Ochroleuca Extract, Niacinamide, Pyrus Malus Fruit Extract, Dimethicone, Cyclopentasiloxane, Trideceth-6, Peg Ppg-18 18 Dimethicone, Sodium Hyaluronate, Hexyldecanol, Caprylic Capric Triglyceride, Disodium Edta, Chlorphenesin, Phenoxyethanol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/hydrabio-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/hydrabio-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/bioderma/hydrabio-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/hydrabio-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/bioderma/hydrabio-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/bioderma/hydrabio-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioderma/hydrabio-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/bioderma/hydrabio-serum/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/bioderma/hydrabio-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/bioderma/hydrabio-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/bioderma/hydrabio-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/bioderma/hydrabio-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/hydrabio-serum/for/combination-skin