# Avène Cicalfate+ Restorative Protective Cream for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Concerning.

Page: https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Avène](https://lovi.care/skincare/es/brands/avene)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing and barrier repair for your combination skin, as glycerin and zinc oxide hydrate and protect without causing irritation. It provides general skincare benefits that are supportive but not targeted for your oily shine concerns due to a lack of specific oil-controlling ingredients.
- The presence of copper sulfate offers antimicrobial action, which is beneficial for combination skin, though stronger humectant support could enhance overall comfort.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Avène Thermal Spring Water, Zinc Oxide, Glycerin, Caprylic Capric Triglyceride, Beeswax

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema. ([Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/))
- Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness. ([Clinical and Experimental Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10671963/))
- Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin. ([Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27102240/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/37109405/))
- Topical application of a honey, olive oil, and beeswax mixture three times daily for up to 4 weeks resulted in clinical responses in 86% of patients with pityriasis versicolor, 78% with tinea cruris, and 75% with tinea corporis. ([Complementary Therapies in Medicine, 2004](https://pubmed.ncbi.nlm.nih.gov/15130571/))
- A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35238152/))
- MUD1 protected human dermal fibroblasts against AAPH-induced oxidative stress by increasing cell viability, reducing oxidative damage, improving mitochondrial functionality, and enhancing wound healing capacities. ([International Journal of Molecular Sciences, 2018](https://pubmed.ncbi.nlm.nih.gov/30235888/))

## What reviewers say

It is also praised for its versatility in healing various skin concerns and its rich, protective texture. However, a significant number of recent reviews mention issues with the product separating into oil and water, and some users with oily or acne-prone skin report clogged pores.

- Liked: Soothes irritation (mostly mentioned)
- Liked: Repairs skin barrier (often mentioned)
- Liked: Rich texture (often mentioned)
- Disliked: Product separation (often mentioned)
- Liked: Versatile healing (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Leaves white cast (sometimes noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Avène Cicalfate+ Cream work for combination skin?

Avène Cicalfate+ Cream works moderately well for combination skin by offering basic hydration and barrier repair through glycerin and zinc oxide without causing irritation. However, it lacks oil-controlling ingredients to properly target oily shine. A product of this type needs targeted oil-controlling ingredients, effective brighteners, strong humectants, and lightweight hydrating agents to best suit combination skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for combination skin?

Glycerin and zinc oxide help make this cream a good fit by hydrating dry areas and protecting the skin without causing irritation, while copper sulfate offers helpful antimicrobial action. However, because it lacks oil-controlling ingredients, combination skin needs products that also feature targeted brightening and oil-reducing agents along with multiple hydrating peptides.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Avène Thermal Spring Water do for combination skin?

Avène Thermal Spring Water helps calm redness and keeps combination skin comfortable by soothing sensitive areas. It is unlikely to cause irritation and supports overall skin balance.
Sources: [Journal of the European Academy of Dermatology and Venereology, 2020](https://pubmed.ncbi.nlm.nih.gov/32870553/), [Journal of the European Academy of Dermatology and Venereology, 2011](https://pubmed.ncbi.nlm.nih.gov/21175867/)

### What does Zinc Oxide do for combination skin?

Zinc oxide helps calm oily and breakout-prone areas while protecting dry spots without clogging pores. This ingredient is unlikely to cause irritation and safely manages shine and redness.
Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Dermatologic Therapy, 2018](https://pubmed.ncbi.nlm.nih.gov/29193602/)

### Where does this cream go in a skincare routine for combination skin?

In an evening routine for combination skin, this cream goes after your treatment and before your moisturizer. A product of this type needs oil-controlling ingredients and stronger hydrating support to better manage oily shine and keep the skin comfortable.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying it as your last step at night to help keep your skin calm and soft. Using a moisturizing cream like this helps your skin tolerate retinol better and reduces dryness, though combination skin also needs oil-controlling ingredients for shine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your routine. Daily application helps improve skin moisture and supports the skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

Yes, this cream may cause breakouts for combination skin, and reviewers moderately complain about this issue. A product of this type needs lighter hydrators and oil-controlling ingredients to properly balance oily shine without clogging pores.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it provides gentle hydration and protection that suits thinner skin areas like the eyelids. Combination skin needing a product of this type requires lightweight moisturizers and oil-controlling ingredients to balance dry patches and oily shine without feeling heavy.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/es/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €13.67 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/es/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €11.50 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/es/p/belif/the-true-cream-aqua-bomb/for/combination-skin) — High fit — €35.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

- Amazon.de: €12.39 (https://www.amazon.de/dp/B07YBCJBG2?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €11.50 (https://www.notino.es/avene/cicalfate-crema-antibacteriana-reparadora-para-rostro-y-cuerpo/p-478226/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Avene Thermal Spring Water Avene Aqua Avene Aqua, Caprylic Capric Triglyceride, Paraffinum Liquidum Mineral Oil, Glycerin, Hydrogenated Oil, Zinc Oxide, Propylene Glycol, Polyglyceryl-2 Sesquiisostearate, Peg-22 Dodecyl Glycol Copolymer, Aluminum Stearate, Aquaphilus Dolomiae Ferment Filtrate, Arginine, Beeswax Cera Alba Cera, Copper Sulfate, Magnesium Stearate, Magnesium Sulfate, Microcrystalline Wax Cera Microcristallina Wax Cera, Tromethamine, Zinc Sulfate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/avene/cicalfate-restorative-protective-cream/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/avene/cicalfate-restorative-protective-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/avene/cicalfate-restorative-protective-cream/for/combination-skin