# APLB Collagen EGF Peptide Ampoule Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [APLB](https://lovi.care/skincare/es/brands/aplb)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, this serum effectively addresses oily shine with niacinamide for sebum regulation and peptides like Rh-Oligopeptide-1 for improved skin texture.
- The inclusion of hydrolyzed collagen and Allantoin further supports barrier repair and hydration, balancing your skin without causing irritation.
- The safety profile is excellent, with no harsh ingredients and a blend of soothing components ensuring a gentle experience for your skin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/oily-acne-prone-skin): High

## Key ingredients

Collagen, Rh-Oligopeptide-1, Peptides

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage. ([Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))

## What reviewers say

Based on limited data, users with dry, sensitive, and aging skin frequently report noticeable improvements in hydration and skin plumpness, often describing a "bouncy" or firming effect. The fragrance-free formula is widely praised for being gentle and absorbing well, though a minority of users find the texture slightly tacky or report that anti-aging results are subtle.

- Liked: Fast absorption (often mentioned)
- Liked: Hydration & Plumping (often mentioned)
- Liked: Excellent value (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Liked: Soothing & Gentle (sometimes noted)
- Disliked: Average results (rarely noted)
- Disliked: Tacky finish (rarely noted)
- Disliked: Thick consistency (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes APLB Collagen EGF Peptide Ampoule Serum a great fit for combination skin?

This serum is a great fit for your combination skin because niacinamide helps control oily shine while peptides improve your skin texture. Hydrolyzed collagen and allantoin also support your moisture barrier and hydration, balancing your skin gently without irritation.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/)

### Which ingredients make this serum a good fit for combination skin?

This serum is a great fit for your combination skin because niacinamide helps control oily shine while peptides improve texture. Hydrolyzed collagen and allantoin also support hydration and repair your skin barrier without causing irritation.
Sources: [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Collagen do for combination skin?

Collagen helps keep combination skin smooth and hydrated by improving moisture and supporting elasticity. It is unlikely to cause irritation and may help reduce the appearance of fine lines while keeping the skin barrier balanced.
Sources: [Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/), [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/)

### What does EGF do for combination skin?

EGF helps support cell turnover and collagen production, which may improve firmness and keep combination skin looking smooth and even. For the best results on combination skin, this ingredient works well alongside hydrating ingredients like hyaluronic acid to balance oilier and dry areas.
Sources: [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30909351/), [Cell Proliferation, 2022](https://pubmed.ncbi.nlm.nih.gov/35274780/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in your evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening helps keep things simple and gives you extra safety around sun exposure.

### Can I use it with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to support hydration and barrier repair, followed by your retinol. The gentle, soothing formulation is unlikely to irritate your skin when layered in this order.

### How often should I use this serum?

This serum is a great fit for your combination skin and is best used in the evening routine. Applying it then keeps things simple and gives you extra safety around sun exposure, though some serums can also be used in the morning or twice a day.

### Can it clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts for your combination skin. It features a very safe blend with niacinamide to help balance oily shine and soothing ingredients that keep irritation low.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Augustinus Bader The Serum](https://lovi.care/skincare/es/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €333.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/combination-skin) — Superior fit — €169.99 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €97.52 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Niacinamide, Hydrolyzed Collagen, Rh-Oligopeptide-1, Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Beta-Glucan, Adenosine, Allantoin, Panthenol, Tocopheryl Acetate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin