# APLB Collagen EGF Peptide Ampoule Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [APLB](https://lovi.care/skincare/es/brands/aplb)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, this serum effectively balances oiliness with niacinamide and hydrates dry areas with sodium hyaluronate, while also offering moderate benefits for your acne and blemishes through niacinamide and Rh-Oligopeptide-1's anti-inflammatory and skin repair properties.
- The inclusion of Hydrolyzed Collagen, Rh-Oligopeptide-1, and Palmitoyl Pentapeptide-4 provides excellent firming and plumping effects, contributing to visible anti-aging results.
- The product is safe for your acne-prone skin, featuring soothing ingredients like Niacinamide and Beta-Glucan with no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/oily-acne-prone-skin): High

## Key ingredients

Collagen, Rh-Oligopeptide-1, Peptides

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- Combined therapy using a topical hyaluronic acid-niacinamide-Matrixyl serum and a multimodal facial device decreased TruSkin age by five years and reduced wrinkles more effectively than the serum alone in a 41-year-old woman with moderate facial aging over 12 weeks. ([Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/))
- A functionalized dendrimer nanocarrier delivers active ingredients into the dermis and enhances collagen production in human dermal fibroblasts by co-delivering all-trans retinol and palmitoyl pentapeptide-4. ([Acta Biomaterialia, 2025](https://pubmed.ncbi.nlm.nih.gov/39694719/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical epidermal growth factor combined with silver sulfadiazine accelerated the rate of epidermal regeneration and significantly decreased healing time by approximately 1 to 1.5 days across all stages of healing in skin-graft-donor sites of 12 patients compared to silver sulfadiazine alone. ([The New England Journal of Medicine, 1989](https://pubmed.ncbi.nlm.nih.gov/2659995/))
- Topical recombinant human epidermal growth factor combined with ablative fractional carbon dioxide laser significantly improved striae surface texture and showed significantly greater participant satisfaction regarding marked improvement compared to ablative fractional carbon dioxide laser combined with Aloe vera gel in patients with striae alba. ([Lasers in Surgery and Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/30614013/))
- Topical EGF combined with fractional CO2 laser significantly improves the clinical appearance of atrophic acne scars and decreases skin pigmentation compared to fractional CO2 laser alone in patients with atrophic acne scars. ([The Journal of Clinical and Aesthetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35942017/))

## What reviewers say

Based on limited data, users with dry, sensitive, and aging skin frequently report noticeable improvements in hydration and skin plumpness, often describing a "bouncy" or firming effect. The fragrance-free formula is widely praised for being gentle and absorbing well, though a minority of users find the texture slightly tacky or report that anti-aging results are subtle.

- Liked: Fast absorption (often mentioned)
- Liked: Hydration & Plumping (often mentioned)
- Liked: Excellent value (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Liked: Soothing & Gentle (sometimes noted)
- Disliked: Average results (rarely noted)
- Disliked: Tacky finish (rarely noted)
- Disliked: Thick consistency (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes APLB Collagen EGF Peptide Ampoule Serum a great fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because it calms blemishes with niacinamide and helps repair the skin while keeping irritation away with soothing beta-glucan. It also balances oil and dry spots effectively, leaving your face feeling smooth.

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because it contains niacinamide and Rh-oligopeptide-1, which help calm blemishes and support skin repair. It is also safe for your skin type with soothing ingredients like beta-glucan that carry no risk of irritation.

### What does Collagen do for acne-prone skin?

Collagen does not directly target breakouts, but it helps keep dry or aging acne-prone skin soft and hydrated without clogging pores. Because this skin type often needs lightweight moisture and soothing care, a product of this type needs non-greasy hydrators and calming ingredients to support clear skin.
Sources: [Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### What does EGF do for acne-prone skin?

EGF helps calm acne-prone skin by reducing both inflamed and non-inflamed breakouts. It supports skin healing and barrier repair, making it a useful option for improving overall skin texture.
Sources: [International Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24962549/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine, as treatments with active ingredients are placed then for simplicity and extra safety around sun exposure. It is safe for your acne-prone skin and is unlikely to cause irritation.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to hydrate and soothe your skin before following with retinol. Niacinamide and beta-glucan help calm the skin, which may reduce the irritation sometimes caused by retinoids.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

This serum is used in the evening for your acne-prone skin, following your cleanser and toner. It is unlikely to cause irritation and helps calm blemishes while keeping skin smooth and firm.
Sources: [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/), [Cureus, 2026](https://pubmed.ncbi.nlm.nih.gov/42500768/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for acne-prone skin because it includes soothing ingredients like niacinamide and beta-glucan with a low risk of irritation. It helps calm blemishes while keeping skin hydrated and balanced.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

No store in Spain has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Niacinamide, Hydrolyzed Collagen, Rh-Oligopeptide-1, Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Beta-Glucan, Adenosine, Allantoin, Panthenol, Tocopheryl Acetate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/aplb/collagen-egf-peptide-ampoule-serum/for/acne-prone-skin