# Anua PDRN Hyaluronic Acid Capsule 100 Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Anua](https://lovi.care/skincare/es/brands/anua)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/es/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other moisturizers fit it better.

## Why this fit

- Suitable for normal skin, this serum leverages multiple forms of hyaluronic acid and glycerin to provide excellent humectant action, complemented by niacinamide for barrier support, which is beneficial for your redness and irritation.
- While it offers general skincare benefits like hydration, it lacks specialized ingredients such as Centella Asiatica or Green Tea Extract to directly target and soothe your sensitivity.
- The safety profile is excellent, with no risks of irritation for your sensitive skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/oily-acne-prone-skin): High

## Key ingredients

Hydrolyzed Hyaluronic Acid, Niacinamide, Glutathione

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Polyelectrolyte nanocomplexes of quaternized cyclodextrin grafted chitosan and low molecular weight hyaluronic acid improved skin texture and elasticity by increasing skin hydration in clinical evaluation. ([Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))

## Why other moisturizers fit sensitive skin better

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A dexpanthenol-containing cream accelerated skin barrier repair, increased stratum corneum hydration, reduced skin roughness, and decreased skin redness compared to vehicle and untreated controls in sodium lauryl sulphate-irritated skin. ([The Journal of Dermatological Treatment, 2002](https://pubmed.ncbi.nlm.nih.gov/19753737/))

## What reviewers say

Users consistently praise this serum for delivering the coveted "glass skin" look, offering deep hydration that plumps the skin without feeling heavy or greasy. While most find it excellent for barrier repair and instant glow, a minority feel it is simply a good hydrator rather than a "life-changing" treatment for the price.

- Liked: Deep hydration (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Makeup compatibility (sometimes noted)
- Liked: Soothing & repair (sometimes noted)
- Disliked: Price vs volume (sometimes noted)
- Disliked: Breakouts (rarely noted)
- Disliked: Runny consistency (rarely noted)
- Disliked: Subtle results (rarely noted)
- Disliked: Texture issues (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Anua PDRN Hyaluronic Acid Capsule 100 Serum work for sensitive skin?

This serum works for sensitive skin by delivering good hydration and barrier support, though other products fit it better because it lacks specialized soothing ingredients like Centella Asiatica or Green Tea Extract. A product of this type needs calming plant extracts and barrier-strengthening ingredients to truly comfort sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a fair fit for sensitive skin because it uses multiple forms of hyaluronic acid and glycerin to boost hydration, along with niacinamide to help support your skin barrier. It is unlikely to cause irritation, but a product of this type for sensitive skin also needs calming ingredients like centella asiatica or green tea extract to actively soothe redness and sensitivity.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Hydrolyzed Hyaluronic Acid do for sensitive skin?

Hydrolyzed hyaluronic acid helps hydrate and calm sensitive skin while improving skin texture. It is unlikely to cause irritation due to its very good safety profile.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your soothing toner and before your moisturizer. It is unlikely to cause irritation for your sensitive skin due to its safe ingredients, though this skin type needs soothing additions like Centella Asiatica or Green Tea Extract for best results.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it after your toner and before your moisturizer in your evening routine. It is unlikely to cause irritation on sensitive skin due to its very safe ingredient profile, though this skin type generally does better with serums that also include soothing ingredients like centella asiatica or green tea extract.

### How often should I use this serum?

This serum works well in your evening routine, but a product for sensitive skin needs calming ingredients like Centella Asiatica or Green Tea Extract to directly soothe irritation.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts on sensitive skin, as it has an excellent safety profile without harsh or irritating ingredients. To truly calm sensitive skin, a moisturizing treatment of this type needs soothing ingredients like Centella Asiatica or Green Tea Extract.

### Can I use this serum around the eyes or on my body?

This serum is safe to use around the eyes and on the body because it has a very safe formula with no harsh ingredients that could cause irritation. However, because sensitive skin needs extra calming care in those delicate or dry areas, a product of this type works best there when it also includes soothing ingredients like Centella Asiatica or Green Tea Extract.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/es/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/sensitive-skin) — High fit — €39.50 at Notino
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/es/p/missha/super-aqua-ultra-hyalron-ampoule/for/sensitive-skin) — Average fit — €20.00 at Notino

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — €39.80 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/es/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.13 at Amazon

## Where to buy

- Amazon.de: €22.00 (https://www.amazon.de/dp/B0DSVF8HGZ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €18.40 (https://www.lookfantastic.es/p/anua-pdrn-hyaluronic-acid-capsule-100-serum-30ml/16674990/)
- Notino: €25.90 (https://www.notino.es/anua/pdrn-hyaluronic-acid-capsule-100-serum-serum-hidratante-nutritivo-con-colageno/p-16313399/)
Prices checked 16 Oct – 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Propanediol, Glycerin, Hydrolyzed Hyaluronic Acid, 1,2-Hexanediol, Niacinamide, Glyceryl Oleate, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Hydrogenated Lecithin, Glutathione, Hydrolyzed Collagen, Hyaluronic Acid, Coptis Japonica Root Extract, Adenosine, Sodium Dna, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Citric Acid, Curcuma Longa Root Extract, Corallina Officinalis Extract, Sodium Citrate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/sensitive-skin