# Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Anua](https://lovi.care/skincare/es/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate brightening and evening of skin tone for your normal skin due to the presence of niacinamide and tranexamic acid, which help regulate melanogenesis and provide antioxidant activity.
- While it provides general hydration benefits from ingredients like glycerin and sodium hyaluronate, these are mostly supportive and not directly targeted at your primary concern of wrinkles and fine lines.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Tranexamic Acid, Arbutin, Sodium Hyaluronate, Centella Asiatica Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## Why other serums fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))

## What reviewers say

Based on a very large amount of data, users consistently praise this serum for its ability to fade stubborn hyperpigmentation and post-acne marks while delivering a radiant glow. A notable minority experiences a sticky residue or skin irritation due to the high concentration of active ingredients.

- Liked: Fades dark spots (mostly mentioned)
- Liked: Brightens complexion (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: Sticky residue (often mentioned)
- Liked: Hydrating finish (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Anua Dark Spot Correcting Serum work for mature skin?

This serum works moderately well for mature skin because ingredients like niacinamide and tranexamic acid help even out skin tone while glycerin and sodium hyaluronate provide general hydration. However, it is an average fit because it lacks targeted ingredients for your primary concern of wrinkles and fine lines. A product for mature skin needs potent antioxidants, hydrating components, and skin-repairing ingredients that effectively target wrinkles and fine lines to improve skin elasticity.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for mature skin?

Niacinamide and tranexamic acid make this serum a fit by helping brighten and even out skin tone. To work best for mature skin, a product of this type needs ingredients that effectively target wrinkles and fine lines, improve skin elasticity, and provide deep hydration.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Tranexamic Acid do for mature skin?

Tranexamic acid helps reduce brown spots and uneven tone while improving overall skin brightness. Studies show that using it regularly can fade stubborn pigmentation safely and with very little irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38549196/), [Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. This mature skin needs a product of this type that also targets wrinkles and fine lines with firming peptides, retinoids, or antioxidants.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying your retinol first and following it with this serum, or by using your retinol at night and this serum in the morning. This serum is safe for your skin and is unlikely to cause irritation, but to truly target wrinkles and fine lines, mature skin needs dedicated anti-aging ingredients like retinol, peptides, or concentrated antioxidants.

### How often should I use this serum?

You can use this treatment in the evening. A mature skin routine like this needs potent anti-aging ingredients such as retinoids, peptides, or antioxidants to target wrinkles and fine lines.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum may cause breakouts for mature skin, as some reviewers note this issue. To help prevent clogged pores, mature skin needs lightweight, non-comedogenic hydrators and gentle smoothing ingredients that do not leave a heavy, sticky residue.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €169.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/es/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.80 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/es/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.00 at Amazon
- Moisturizer: [Shiseido Benefiance Wrinkle Smoothing Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-cream-enriched/for/mature-skin) — Superior fit — €57.95 at Amazon

## Where to buy

- Amazon.de: €18.70 (https://www.amazon.de/dp/B0DL92QM79?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €30.90 (https://www.notino.es/anua/niacinamide-10-txa-4-dark-spot-correcting-serum-serum-iluminador-para-unificar-el-tono-de-la-piel/p-16268710/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Niacinamide, Tranexamic Acid, Butylene Glycol, Diethoxyethyl Succinate, 1,2-Hexanediol, Arbutin, Sodium Hyaluronate, Alpha-Arbutin, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Macadamia Ternifolia Seed Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Jojoba Seed Oil, Vitis Vinifera Seed Oil Grape Seed Oil, Theobroma Cacao Extract, Hydrolyzed Hyaluronic Acid, Chamaecyparis Obtusa Leaf Extract, Prunus Persica Flower Extract, Camellia Sinensis Seed Oil, Yeast Extract Ferment, Centella Asiatica Extract, Artemisia Princeps Leaf Extract, Candida Bombicola Glucose Methyl Rapeseedate Ferment, Pentylene Glycol, Betaine Salicylate, Sucrose Palmitate, Hydrogenated Lecithin, Gellan Gum, Sodium Phytate, Cellulose, Caprylic Capric Triglyceride, Panthenol, Cyanocobalamin, Polyglutamic Acid, 3-O-Ethyl Ascorbic Acid, Ceramide Np, Dextrin, Asiaticoside, Madecassic Acid, Asiatic Acid, Dimethylsilanol Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin
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- Netherlands: https://lovi.care/skincare/nl/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/niacinamide-10-txa-4-dark-spot-correcting-serum/for/mature-skin