# Anua Nano Retinol 0.3% + Niacin Renewing Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Anua](https://lovi.care/skincare/es/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate exfoliation and skin renewal for your oily skin due to retinol and BHA, which help improve texture and tone. Niacinamide also aids in seboregulation, providing general benefits for oily skin.
- While the serum offers hydration and soothing effects from ingredients like Centella Asiatica extract, it lacks targeted ingredients for significant oil control, which is your main concern.
- The product is safe for your oily skin, as it contains soothing ingredients like niacinamide and centella asiatica and avoids harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Niacinamide, Centella Asiatica Extract, Sodium Hyaluronate, Ceramide Np

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit oily skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users find this serum to be an excellent gentle introduction to retinol, effectively smoothing skin texture and refining pores with minimal irritation. While improvements to fine lines and blackheads require consistent use, the formula hydrates and plumps the skin, leaving it glowing and moisturized.

- Liked: Gentle & non-irritating (often mentioned)
- Liked: Improves texture & pores (often mentioned)
- Liked: Brightening effect (sometimes noted)
- Liked: Elegant texture (sometimes noted)
- Liked: Hydrating & plumping (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Initial sensitivity (rarely noted)
- Disliked: Scent preferences (rarely noted)
- Disliked: Small quantity (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Anua Nano Retinol 0.3% + Niacin Renewing Serum work for oily skin?

This serum is an average fit for your oily skin because while it provides helpful renewal and calming effects, it lacks targeted ingredients for significant oil control. Treatments that work better for oily skin need ingredients like niacinamide, zinc PCA, and balancing extracts to actively manage excess oil and shine.

### Which ingredients make this serum a good fit for oily skin?

This serum fits oily skin by including retinol and BHA for texture and tone, along with niacinamide to help manage oil and centella asiatica extract to calm the skin. To work best for oily skin, a product of this type needs targeted oil-controlling ingredients, powerful sebum regulators like zinc PCA, and antioxidants such as ferulic acid to manage shine and pores effectively.

### What does Retinol do for oily skin?

Retinol helps oily skin by keeping pores clear and balancing sebum production, which may reduce shine and breakouts. Because it can sometimes cause dryness or peeling in the beginning, starting slowly is recommended.
Sources: [Biochimica Et Biophysica Acta, 2012](https://pubmed.ncbi.nlm.nih.gov/21914489/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for oily skin?

This treatment serum goes in your evening routine, applied after cleansing and before your moisturizer. Putting it in the evening helps keep your skin safe from sun exposure while delivering active ingredients like retinol and niacinamide. Oily skin also needs targeted ingredients for oil control to fully address excess shine.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C, but it is best to apply them at different times of day or alternate days to prevent skin irritation. Using both potent ingredients at once may cause redness or dryness for oily skin, so starting slowly helps your skin adjust safely.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Start using this treatment once a week in the evening, and if your oily skin tolerates it well and sees good results, you can carefully use it more often. Oily skin works best with products of this type that also include powerful oil-absorbing and sebum-balancing ingredients.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38406974/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts on oily skin, though the retinol may cause mild initial purging as it renews the skin. Soothing ingredients like niacinamide and centella asiatica help keep irritation low.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — €169.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — €29.76 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — €29.76 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €20.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €17.49 at Amazon

## Where to buy

- Amazon.de: €34.00 (https://www.amazon.de/dp/B0CRSZDX59?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycereth-26, Niacinamide, Pyrus Malus Fruit Extract, Glycerin, 1,2-Hexanediol, Caprylic Capric Triglyceride, Chestnut Shell Extract, Glyceryl Citrate Lactate Linoleate Oleate, Diospyros Kaki Leaf Extract, Coptis Japonica Root Extract, Potentilla Anserina Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Cynara Scolymus Leaf Extract, Portulaca Oleracea Extract, Melaleuca Alternifolia Tree Extract, Ficus Carica Fruit Extract, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Artemisia Capillaris Flower Extract, Arnica Montana Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Chamomilla Recutita Leaf Extract Flower Matricaria Leaf Extract Flower, Borago Officinalis Extract, Centaurea Cyanus Flower Extract, Hydrogenated Lecithin, Camellia Sinensis Leaf Water, Centaurea Cyanus Flower Water, Sodium Hyaluronate, Melaleuca Alternifolia Tree Oil Leaf, Carapa Guianensis Seed Oil, Hippophae Rhamnoides Oil Fruit, Tocopherol, Propanediol, Cetyl Ethylhexanoate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyacrylate Crosspolymer-6, Methylpropanediol, Butylene Glycol, Polysorbate 20, Retinol, Ceramide Np, Pentylene Glycol, Carbomer, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Adenosine, Disodium Edta, Polyquaternium-51, Beta-Glucan, Squalane, Panthenol, Hydrolyzed Sodium Hyaluronate, Bht, Oleic Acid, Dipropylene Glycol, Bha, Allantoin, Maltodextrin, Saccharide Hydrolysate, Sorbitan Laurate, Glyceryl Stearate, Butyrospermum Parkii Butter Shea Butter, Octyldodecanol, Phytosterols, Madecassoside, Ceramide, Ceramide Ap, Capryloyl Salicylic Acid, Cholesterol, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Ceramide Ns, Ceramide Ng, Caprylyl Glycol, Guaiazulene, Sucrose Distearate, Nonapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Hydroxypropyl Cyclodextrin, Hexapeptide-9, Ceramide Eop
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin