# Anua Nano Retinol 0.3% + Niacin Renewing Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Anua](https://lovi.care/skincare/es/brands/anua)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate renewal for your dry and sensitive skin, as retinol and niacinamide work to smooth texture and even tone, while glycerin and centella asiatica extract provide essential hydration and soothing.
- The inclusion of sodium hyaluronate and squalane further supports your dry skin by offering humectant and emollient benefits to hydrate and smooth.
- The product is safe for your skin due to the absence of harsh ingredients and the presence of soothing components like niacinamide and centella asiatica.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/oily-acne-prone-skin): High

## Key ingredients

Retinol, Niacinamide, Centella Asiatica Extract, Sodium Hyaluronate, Ceramide Np

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users find this serum to be an excellent gentle introduction to retinol, effectively smoothing skin texture and refining pores with minimal irritation. While improvements to fine lines and blackheads require consistent use, the formula hydrates and plumps the skin, leaving it glowing and moisturized.

- Liked: Gentle & non-irritating (often mentioned)
- Liked: Improves texture & pores (often mentioned)
- Liked: Brightening effect (sometimes noted)
- Liked: Elegant texture (sometimes noted)
- Liked: Hydrating & plumping (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Initial sensitivity (rarely noted)
- Disliked: Scent preferences (rarely noted)
- Disliked: Small quantity (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Anua Nano Retinol 0.3% + Niacin Renewing Serum work for dry sensitive skin?

This serum works moderately well for your dry sensitive skin, as retinol and niacinamide help smooth texture while glycerin, centella asiatica, and sodium hyaluronate keep your skin calm and hydrated. Treatments that fit dry sensitive skin best need gentle, deeply moisturizing ingredients like ceramides and nourishing oils that deliver rich hydration and support your skin barrier without any risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Retinol and niacinamide smooth texture and even tone, while glycerin, squalane, sodium hyaluronate, and centella asiatica extract help hydrate and calm your dry sensitive skin. A product of this type needs maximum beneficial hydrating and nourishing ingredients, skin barrier support like ceramides, and optimal textures that improve moisture retention without any risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Retinol do for dry sensitive skin?

Retinol is often too strong for dry sensitive skin because it may cause scaling and stinging, so a product of this type needs gentle soothing ingredients and extra moisture to keep the skin calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment serum goes in the evening routine after your soothing toner and before your moisturizer. A product of this type needs calming ingredients and extra moisture boosters to keep dry and sensitive skin comfortable.

### Can I use this serum with vitamin C, and in what order?

You can use this serum with vitamin C by applying vitamin C in your morning routine and this treatment serum at night to help avoid irritation on dry sensitive skin. A product of this type for dry sensitive skin needs extra soothing and hydrating ingredients like ceramides, squalane, and centella asiatica to keep the skin calm and comfortable.

### How often should I use this serum?

This serum works well when used in the evening as part of your routine. A product of this type needs soothing ingredients like centella asiatica and rich hydrators like glycerin or ceramides to keep dry and sensitive skin comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum may cause mild purging when you first start using it due to the retinol, but it is unlikely to clog pores. A product for dry sensitive skin needs soothing ingredients like centella asiatica extract and nourishing oils to keep the skin calm and hydrated without causing breakouts.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €169.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/es/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — €57.00 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/es/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/es/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/es/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €23.99 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €16.99 at Amazon

## Where to buy

- Amazon.de: €34.00 (https://www.amazon.de/dp/B0CRSZDX59?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycereth-26, Niacinamide, Pyrus Malus Fruit Extract, Glycerin, 1,2-Hexanediol, Caprylic Capric Triglyceride, Chestnut Shell Extract, Glyceryl Citrate Lactate Linoleate Oleate, Diospyros Kaki Leaf Extract, Coptis Japonica Root Extract, Potentilla Anserina Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Cynara Scolymus Leaf Extract, Portulaca Oleracea Extract, Melaleuca Alternifolia Tree Extract, Ficus Carica Fruit Extract, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Artemisia Capillaris Flower Extract, Arnica Montana Flower Extract, Houttuynia Cordata Extract, Melia Azadirachta Leaf Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Chamomilla Recutita Leaf Extract Flower Matricaria Leaf Extract Flower, Borago Officinalis Extract, Centaurea Cyanus Flower Extract, Hydrogenated Lecithin, Camellia Sinensis Leaf Water, Centaurea Cyanus Flower Water, Sodium Hyaluronate, Melaleuca Alternifolia Tree Oil Leaf, Carapa Guianensis Seed Oil, Hippophae Rhamnoides Oil Fruit, Tocopherol, Propanediol, Cetyl Ethylhexanoate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Polyacrylate Crosspolymer-6, Methylpropanediol, Butylene Glycol, Polysorbate 20, Retinol, Ceramide Np, Pentylene Glycol, Carbomer, Tromethamine, Dipotassium Glycyrrhizate, Ethylhexylglycerin, Adenosine, Disodium Edta, Polyquaternium-51, Beta-Glucan, Squalane, Panthenol, Hydrolyzed Sodium Hyaluronate, Bht, Oleic Acid, Dipropylene Glycol, Bha, Allantoin, Maltodextrin, Saccharide Hydrolysate, Sorbitan Laurate, Glyceryl Stearate, Butyrospermum Parkii Butter Shea Butter, Octyldodecanol, Phytosterols, Madecassoside, Ceramide, Ceramide Ap, Capryloyl Salicylic Acid, Cholesterol, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Ceramide Ns, Ceramide Ng, Caprylyl Glycol, Guaiazulene, Sucrose Distearate, Nonapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Hydroxypropyl Cyclodextrin, Hexapeptide-9, Ceramide Eop
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/nano-retinol-0-3-niacin-renewing-serum/for/dry-sensitive-skin