# Allies of Skin Copper Tripeptide & Ectoin Advanced Repair Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Brand: [Allies of Skin](https://lovi.care/skincare/es/brands/allies-of-skin)
Category: [Serums and treatments](https://lovi.care/skincare/es/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers excellent skin repair for your combination skin, as copper tripeptide-1 and ectoin enhance barrier resilience and minimize fine lines, while niacinamide reduces inflammation and supports acne repair.
- Hyaluronic acid and panthenol further contribute to hydration and soothing, complementing the primary actives for overall skin health.
- The formulation is safe for your acne-prone skin, with no harsh ingredients and the inclusion of soothing agents like niacinamide and ectoin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/oily-acne-prone-skin): High

## Key ingredients

Copper Tripeptide-1, Ectoin, Niacinamide, Hyaluronic Acid, Panthenol

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Combining ectoine and mannitol with UV filters significantly improved protection of squalene oxidation, catalase activity, and trans-UCA compared to UV filters alone in 10 subjects on irradiated areas. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37539499/))
- Topical 7% ectoine during serial 1064-nm Nd:YAG laser therapy produced a greater reduction in skin erythema, improved stratum corneum hydration, reduced transepidermal water loss, and decreased low-echogenic pixels in thirty participants compared to a vehicle control. ([Biomedicines, 2026](https://pubmed.ncbi.nlm.nih.gov/42792808/))
- Regular application of a novel anti-ageing cream containing hyaluronic acid, ectoin, and botanical actives significantly reduced wrinkle depth and length in the periorbital area while demonstrating very good skin tolerance. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Users consistently report a healthier, more radiant complexion and smoother texture, though the high price point is frequently noted as the primary drawback.

- Liked: Calms redness (often mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Disliked: High price (often mentioned)
- Liked: Fast results (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Initial irritation (rarely noted)
- Disliked: Slow anti-aging results (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Allies of Skin Advanced Repair Serum a great fit for acne-prone skin?

Allies of Skin Copper Tripeptide & Ectoin Advanced Repair Serum is a great fit for acne-prone skin because it uses niacinamide to reduce inflammation and support acne repair while copper tripeptide-1 and ectoin strengthen your skin barrier. It also includes soothing agents and hydrating ingredients that keep your skin calm and moisturized without any harsh elements.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for acne-prone skin?

Niacinamide, ectoin, and copper tripeptide-1 make this serum a great fit by reducing inflammation and supporting acne repair while strengthening your skin. Hyaluronic acid and panthenol further help by calming your skin and keeping it hydrated.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Copper Tripeptide-1 do for acne-prone skin?

Copper Tripeptide-1 helps calm acne-prone skin by reducing inflammation and supporting overall skin repair. Because this is a weaker match for your skin, an ideal product of this type needs soothing ingredients and gentle hydrators to calm irritation without clogging pores.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [International Journal of Molecular Sciences, 2018](https://pubmed.ncbi.nlm.nih.gov/29986520/)

### What does Ectoin do for acne-prone skin?

Ectoin helps acne-prone skin by acting as a protective agent that calms irritation and strengthens the skin barrier. It is unlikely to clog pores and may help keep skin smooth and comfortable while you manage breakouts. Acne-prone skin of this type needs lightweight hydrators and soothing ingredients to balance moisture without feeling heavy or greasy.
Sources: [Clinics in Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18691511/), [Arhiv Za Higijenu Rada I Toksikologiju, 2016](https://pubmed.ncbi.nlm.nih.gov/28033102/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment serum goes in your evening routine, applied after cleansing and before your moisturizer. Using it at night keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to calm your skin and strengthen its barrier before adding retinol. This combination is safe for acne-prone skin because the soothing ingredients help reduce irritation while you treat breakouts.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Use this treatment in your evening routine, as recommended for simplicity and extra safety around sun exposure. This serum is safe for your acne-prone skin and helps soothe irritation without harsh ingredients.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is safe for your acne-prone skin and is unlikely to clog pores or cause breakouts. Its formulation avoids harsh ingredients and includes soothing agents like niacinamide and ectoin to help calm your skin.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/es/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/es/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — €29.76 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/es/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — €21.99 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/es/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €11.99 at Amazon
- Hydrating Toner: [Paula's Choice Resist Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/acne-prone-skin) — Superior fit — €34.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/es/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €17.49 at Amazon

## Where to buy

- Lookfantastic: €218.50 (https://www.lookfantastic.es/p/allies-of-skin-copper-tripeptide-ectoin-advanced-repair-serum-30ml/15298414/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Glycerin, Niacinamide, Copper Tripeptide-1, Ectoin, Hyaluronic Acid, Panthenol, Lactobacillus Ferment, Sodium Pca, Allantoin, Tocopherol Vitamin E, Sodium Ascorbyl Phosphate Ascorbic Acid, Phenoxyethanol, Ethylhexylglycerin, Caprylyl Glycol, Xanthan Gum, Carbomer, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin (this page)
- Canada: https://lovi.care/skincare/ca/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/allies-of-skin/copper-tripeptide-and-ectoin-advanced-repair-serum/for/acne-prone-skin