# Retinol and niacinamide

Page: https://lovi.care/skincare/es/ingredients/retinol-and-niacinamide

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Depends on the strength

Use [niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide) in the morning and [retinol](https://lovi.care/skincare/es/ingredients/retinol) at night, because this prevents redness and helps your skin adjust. Niacinamide calms irritation and strengthens your moisture barrier, while retinol boosts cell renewal. You can choose a gentler formula or wait longer between applications if your skin feels sensitive.

[Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects](https://pubmed.ncbi.nlm.nih.gov/28318351/) [Why Topical Retinoids Are Mainstay of Therapy for Acne](https://pubmed.ncbi.nlm.nih.gov/28585191/)

- [All about retinol](https://lovi.care/skincare/es/ingredients/retinol)
- [All about niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide)

### [Retinol](https://lovi.care/skincare/es/ingredients/retinol) products

- [RoC Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/es/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [€33.98 at Amazon](https://www.amazon.de/dp/B0GXBBV93V?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Paula's Choice 1% Retinol Treatment](https://lovi.care/skincare/es/p/paula-s-choice/1-retinol-treatment/for/dark-spots) — Superior fit — [€57.00 at Amazon](https://www.amazon.de/dp/B07P6M914G?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [RoC Retinol Correxion Line Smoothing Eye Cream](https://lovi.care/skincare/es/p/roc/retinol-correxion-line-smoothing-eye-cream/for/mature-skin) — High fit — [€19.99 at Amazon](https://www.amazon.de/dp/B08GGD7NRN?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Good Molecules Gentle Retinol Cream](https://lovi.care/skincare/es/p/good-molecules/gentle-retinol-cream/for/mature-skin) — High fit — [€25.39 at Amazon](https://www.amazon.de/dp/B09BST7MMP?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [DRMTLGY Retinol Body Lotion](https://lovi.care/skincare/es/p/drmtlgy/retinol-body-lotion/for/mature-skin) — Average fit
- [RoC Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/es/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [€30.97 at Amazon](https://www.amazon.de/dp/B0GQZ5J61H?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [cocokind Retinol Body Cream](https://lovi.care/skincare/es/p/cocokind/retinol-body-cream/for/mature-skin) — Average fit
- [Neutrogena Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/es/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit
- [The Ordinary Granactive Retinoid 2% Emulsion](https://lovi.care/skincare/es/p/the-ordinary/granactive-retinoid-2-emulsion/for/oily-skin) — High fit — [€12.00 at Amazon](https://www.amazon.de/dp/B071HHSMTT?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Murad Retinol Youth Renewal Serum](https://lovi.care/skincare/es/p/murad/retinol-youth-renewal-serum/for/mature-skin) — Average fit
- [Dr. Dennis Gross Alpha Beta Universal Daily Peel](https://lovi.care/skincare/es/p/dr-dennis-gross/alpha-beta-universal-daily-peel/for/acne-prone-skin) — Superior fit — [€175.00 at Amazon](https://www.amazon.de/dp/B009QZ595Q?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [COSRX The Retinol 0.1 Cream](https://lovi.care/skincare/es/p/cosrx/the-retinol-0-1-cream/for/oily-skin) — High fit — [€17.90 at Amazon](https://www.amazon.de/dp/B0B5DKJ8TS?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### [Niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide) products

- [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/es/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/es/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€20.50 at Amazon](https://www.amazon.de/dp/B01N1LL62W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/es/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [€15.19 at Amazon](https://www.amazon.de/dp/B0GKQNQ5FK?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/es/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€19.75 at Amazon](https://www.amazon.de/dp/B0052EM8L8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/es/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [€9.99 at Amazon](https://www.amazon.de/dp/B0G643D8ZG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/es/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [€12.46 at Amazon](https://www.amazon.de/dp/B0B2RM68G2?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/es/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [€22.99 at Amazon](https://www.amazon.de/dp/B0012J30LY?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/es/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€6.00 at Notino](https://www.notino.es/cerave/moisturizers-leche-facial-y-corporal-hidratante-para-pieles-secas-y-muy-secas/p-16298665/)
- [Medicube PDRN Pink Peptide Serum](https://lovi.care/skincare/es/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [€16.60 at Amazon](https://www.amazon.de/dp/B0DBF65JYY?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [CeraVe Renewing SA Cleanser](https://lovi.care/skincare/es/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [€16.25 at Amazon](https://www.amazon.de/dp/B09MMJS8ZM?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Medicube Collagen Jelly Cream](https://lovi.care/skincare/es/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [€14.48 at Amazon](https://www.amazon.de/dp/B0F4PNBXLZ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Olay Super Serum](https://lovi.care/skincare/es/p/olay/super-serum/for/dry-skin) — High fit — [€27.38 at Amazon](https://www.amazon.de/dp/B0FM8VTDXL?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use retinol and niacinamide together?

Yes, you can use [retinol](https://lovi.care/skincare/es/ingredients/retinol) and [niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide) together depending on the strength, and products like innisfree Retinol Cica Repair Ampoule and Alastin Skincare Restorative Skin [Complex](https://lovi.care/skincare/es/ingredients/complex) combine them. Niacinamide helps reduce the irritation and redness that retinol may cause while improving skin tolerance. You can use niacinamide in the morning and retinol at night, or choose products that combine them safely.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/) [The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/)

### Which goes first, retinol or niacinamide?

Using niacinamide in the morning and retinol at night helps reduce irritation and improve skin tolerance. Products like innisfree Retinol Cica Repair Ampoule, Alastin Skincare Restorative Skin Complex, SkinMedica Retinol Complex, Olay Advanced Eye Cream, Palmer's Skin Success Anti-Dark Spot Fade Cream, and SHANI DARDEN Retinol Reform combine these ingredients.

### Are retinol and niacinamide good for sensitive skin?

Yes, retinol and niacinamide are generally good for sensitive skin depending on the strength, because niacinamide helps reduce irritation and enhances barrier repair. Products like innisfree Retinol Cica Repair Ampoule, Alastin Skincare Restorative Skin Complex, SkinMedica Retinol Complex, Olay Advanced Eye Cream, Palmer's Skin Success Anti-Dark Spot Fade Cream, and SHANI DARDEN Retinol Reform combine these ingredients.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Research on retinol and niacinamide

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Encapsulation and controlled release of retinol from silicone particles for topical delivery](https://pubmed.ncbi.nlm.nih.gov/29604311/) Retinol · Journal of Controlled Release, 2018
- [A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen](https://pubmed.ncbi.nlm.nih.gov/20374604/) Retinol · The British Journal of Dermatology, 2010
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing](https://pubmed.ncbi.nlm.nih.gov/38685700/) Retinol · International Journal of Cosmetic Science, 2024

## Other combinations

- Keep them apart: [Retinol and isopropyl alcohol](https://lovi.care/skincare/es/ingredients/retinol-and-isopropyl-alcohol)
- Keep them apart: [Retinol and sodium lauryl sulfate](https://lovi.care/skincare/es/ingredients/retinol-and-sodium-lauryl-sulfate)
- Keep them apart: [Retinol and aha blend glycolic and citric acids](https://lovi.care/skincare/es/ingredients/retinol-and-aha-blend-glycolic-and-citric-acids)
- Keep them apart: [Retinol and citric acid](https://lovi.care/skincare/es/ingredients/retinol-and-citric-acid)
- Keep them apart: [Glycolic acid and retinol](https://lovi.care/skincare/es/ingredients/glycolic-acid-and-retinol)
- Keep them apart: [Retinol and lactic acid](https://lovi.care/skincare/es/ingredients/retinol-and-lactic-acid)
- Keep them apart: [Retinol and mandelic acid](https://lovi.care/skincare/es/ingredients/retinol-and-mandelic-acid)
- Keep them apart: [Retinol and salicylic acid](https://lovi.care/skincare/es/ingredients/retinol-and-salicylic-acid)
- Depends on the strength: [AHA blend glycolic and citric acids and niacinamide](https://lovi.care/skincare/es/ingredients/aha-blend-glycolic-and-citric-acids-and-niacinamide)
- Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-citric-acid)
- Depends on the strength: [Glycolic acid and niacinamide](https://lovi.care/skincare/es/ingredients/glycolic-acid-and-niacinamide)
- Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-lactic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-mandelic-acid)
- Depends on the strength: [Niacinamide and salicylic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-salicylic-acid)
- Keep them apart: [Vitamin C and retinol](https://lovi.care/skincare/es/ingredients/vitamin-c-and-retinol)
- Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/es/ingredients/retinol-and-acetyl-hexapeptide-3)
- Depends on the strength: [Retinol and bio-placenta peptides](https://lovi.care/skincare/es/ingredients/retinol-and-bio-placenta-peptides)
- Depends on the strength: [Retinol and collagen peptide](https://lovi.care/skincare/es/ingredients/retinol-and-collagen-peptide)
- Depends on the strength: [Retinol and copper peptide](https://lovi.care/skincare/es/ingredients/retinol-and-copper-peptide)
- Depends on the strength: [Retinol and hexapeptide](https://lovi.care/skincare/es/ingredients/retinol-and-hexapeptide)
- Depends on the strength: [Retinol and hexapeptide-9](https://lovi.care/skincare/es/ingredients/retinol-and-hexapeptide-9)
- Depends on the strength: [Retinol and palmitoyl pentapeptide-4](https://lovi.care/skincare/es/ingredients/retinol-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Retinol and palmitoyl tripeptide-1](https://lovi.care/skincare/es/ingredients/retinol-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Retinol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/retinol-and-peptide-rich-plasma)
- Depends on the strength: [Retinol and triple peptide blend](https://lovi.care/skincare/es/ingredients/retinol-and-triple-peptide-blend)
- Depends on the strength: [Niacinamide and gluconolactone](https://lovi.care/skincare/es/ingredients/niacinamide-and-gluconolactone)
- Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-lactobionic-acid)
- Work well together: [Niacinamide and cholesterol](https://lovi.care/skincare/es/ingredients/niacinamide-and-cholesterol)
- Work well together: [Niacinamide and lauric acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-lauric-acid)
- Work well together: [Niacinamide and linoleic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-linoleic-acid)
- Work well together: [Niacinamide and tri-ceramide complex](https://lovi.care/skincare/es/ingredients/niacinamide-and-tri-ceramide-complex)
- Depends on the strength: [Adapalene and niacinamide](https://lovi.care/skincare/es/ingredients/adapalene-and-niacinamide)
- Depends on the strength: [Niacinamide and granactive retinoid](https://lovi.care/skincare/es/ingredients/niacinamide-and-granactive-retinoid)
- Depends on the strength: [Niacinamide and hydroxypinacolone retinoate](https://lovi.care/skincare/es/ingredients/niacinamide-and-hydroxypinacolone-retinoate)
- Depends on the strength: [Niacinamide and pro-retinol](https://lovi.care/skincare/es/ingredients/niacinamide-and-pro-retinol)
- Depends on the strength: [Niacinamide and retinal](https://lovi.care/skincare/es/ingredients/niacinamide-and-retinal)
- Depends on the strength: [Niacinamide and retinoid blend](https://lovi.care/skincare/es/ingredients/niacinamide-and-retinoid-blend)
- Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/es/ingredients/niacinamide-and-tretinoin)
- Depends on the strength: [Niacinamide and vitamin A](https://lovi.care/skincare/es/ingredients/niacinamide-and-vitamin-a)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/es/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/es/ingredients/niacinamide-and-bio-placenta-peptides)
- Depends on the strength: [Niacinamide and collagen peptide](https://lovi.care/skincare/es/ingredients/niacinamide-and-collagen-peptide)
- Depends on the strength: [Niacinamide and copper peptide](https://lovi.care/skincare/es/ingredients/niacinamide-and-copper-peptide)
- Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/es/ingredients/niacinamide-and-hexapeptide)
- Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/es/ingredients/niacinamide-and-hexapeptide-9)
- Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/es/ingredients/niacinamide-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Niacinamide and palmitoyl tripeptide-1](https://lovi.care/skincare/es/ingredients/niacinamide-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/niacinamide-and-peptide-rich-plasma)
- Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/es/ingredients/niacinamide-and-triple-peptide-blend)
- Work well together: [Retinol and bakuchiol](https://lovi.care/skincare/es/ingredients/retinol-and-bakuchiol)
- Work well together: [Retinol and coenzyme q10](https://lovi.care/skincare/es/ingredients/retinol-and-coenzyme-q10)
- Work well together: [Retinol and green tea](https://lovi.care/skincare/es/ingredients/retinol-and-green-tea)
- Work well together: [Retinol and vitamin E](https://lovi.care/skincare/es/ingredients/retinol-and-vitamin-e)
- Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-hyaluronic-acid)
- Work well together: [Niacinamide and bakuchiol](https://lovi.care/skincare/es/ingredients/niacinamide-and-bakuchiol)
- Work well together: [Niacinamide and zinc](https://lovi.care/skincare/es/ingredients/niacinamide-and-zinc)
- Work well together: [Niacinamide and zinc gluconate](https://lovi.care/skincare/es/ingredients/niacinamide-and-zinc-gluconate)
- Work well together: [Niacinamide and zinc oxide](https://lovi.care/skincare/es/ingredients/niacinamide-and-zinc-oxide)
- Work well together: [Niacinamide and zinc sulfate](https://lovi.care/skincare/es/ingredients/niacinamide-and-zinc-sulfate)
- Work well together: [Benzoyl peroxide and niacinamide](https://lovi.care/skincare/es/ingredients/benzoyl-peroxide-and-niacinamide)
- Keep them apart: [Niacinamide and lipohydroxy acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-lipohydroxy-acid)
- Keep them apart: [Benzoyl peroxide and retinol](https://lovi.care/skincare/es/ingredients/benzoyl-peroxide-and-retinol)
- Work well together: [Ferulic acid and niacinamide](https://lovi.care/skincare/es/ingredients/ferulic-acid-and-niacinamide)
- Work well together: [Green tea and niacinamide](https://lovi.care/skincare/es/ingredients/green-tea-and-niacinamide)
- Work well together: [Niacinamide and vitamin E](https://lovi.care/skincare/es/ingredients/niacinamide-and-vitamin-e)
- Keep them apart: [Niacinamide and isopropyl alcohol](https://lovi.care/skincare/es/ingredients/niacinamide-and-isopropyl-alcohol)
- Work well together: [Retinol and ceramide-building complex](https://lovi.care/skincare/es/ingredients/retinol-and-ceramide-building-complex)
- Work well together: [Retinol and tri-ceramide complex](https://lovi.care/skincare/es/ingredients/retinol-and-tri-ceramide-complex)
- Work well together: [Niacinamide and ascorbyl glucoside](https://lovi.care/skincare/es/ingredients/niacinamide-and-ascorbyl-glucoside)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/retinol-and-niacinamide
- United Kingdom: https://lovi.care/skincare/uk/ingredients/retinol-and-niacinamide
- Ireland: https://lovi.care/skincare/ie/ingredients/retinol-and-niacinamide
- Germany: https://lovi.care/skincare/de/ingredients/retinol-and-niacinamide
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- Italy: https://lovi.care/skincare/it/ingredients/retinol-and-niacinamide
- Netherlands: https://lovi.care/skincare/nl/ingredients/retinol-and-niacinamide
- Spain: https://lovi.care/skincare/es/ingredients/retinol-and-niacinamide (this page)
- Canada: https://lovi.care/skincare/ca/ingredients/retinol-and-niacinamide
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