# Lactic acid and lactobionic acid Page: https://lovi.care/skincare/es/ingredients/lactic-acid-and-lactobionic-acid The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain. Work well together Use them together in the same routine, applying the [lactic acid](https://lovi.care/skincare/es/ingredients/lactic-acid) first and following it with the [lactobionic acid](https://lovi.care/skincare/es/ingredients/lactobionic-acid). Lactic acid exfoliates while lactobionic acid adds moisture and calms potential irritation so your skin stays comfortable. If you experience any sensitivity, you can use a gentler strength or apply them on alternate nights. [The use of polyhydroxy acids (PHAs) in photoaged skin](https://pubmed.ncbi.nlm.nih.gov/15002656/) [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) - [All about lactic acid](https://lovi.care/skincare/es/ingredients/lactic-acid) - [All about lactobionic acid](https://lovi.care/skincare/es/ingredients/lactobionic-acid) ### [Lactic acid](https://lovi.care/skincare/es/ingredients/lactic-acid) products - [Medicube Zero Pore Pad](https://lovi.care/skincare/es/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [€16.98 at Amazon](https://www.amazon.de/dp/B09V7Z4TJG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [First Aid Beauty KP Bump Eraser Body Scrub](https://lovi.care/skincare/es/p/first-aid-beauty/kp-bump-eraser-body-scrub/for/dark-spots) — Average fit — [€25.02 at Amazon](https://www.amazon.de/dp/B08GNS58PQ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [EltaMD UV Clear Broad-Spectrum SPF 46](https://lovi.care/skincare/es/p/eltamd/uv-clear-broad-spectrum-spf-46/for/oily-acne-prone-skin) — Superior fit — [€72.80 at Amazon](https://www.amazon.de/dp/B00ZPWR0N8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [First Aid Beauty Facial Radiance Pads](https://lovi.care/skincare/es/p/first-aid-beauty/facial-radiance-pads/for/sensitive-skin) — Superior fit — [€29.33 at Lookfantastic](https://www.lookfantastic.es/p/first-aid-beauty-brighten-glow-facial-radiance-pads-60-count/17659264/) - [CeraVe SA Lotion for Rough & Bumpy Skin](https://lovi.care/skincare/es/p/cerave/sa-lotion-for-rough-and-bumpy-skin/for/oily-skin) — Average fit — [€21.16 at Lookfantastic](https://www.lookfantastic.es/p/cerave-sa-smoothing-cream-with-salicylic-acid-for-dry-rough-bumpy-skin-340g/12207664/) - [CeraVe Renewing SA Cream](https://lovi.care/skincare/es/p/cerave/renewing-sa-cream/for/oily-acne-prone-skin) — High fit - [The Ordinary Alpha Arbutin 2% + HA](https://lovi.care/skincare/es/p/the-ordinary/alpha-arbutin-2-ha/for/dark-spots) — Superior fit — [€12.39 at Amazon](https://www.amazon.de/dp/B06XCZFCFZ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [The Ordinary Retinal 0.2% Emulsion](https://lovi.care/skincare/es/p/the-ordinary/retinal-0-2-emulsion/for/oily-acne-prone-skin) — High fit — [€17.50 at Amazon](https://www.amazon.de/dp/B0CZ5VG3L1?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Kate Somerville ExfoliKate Intensive Exfoliating Treatment](https://lovi.care/skincare/es/p/kate-somerville/exfolikate-intensive-exfoliating-treatment/for/mature-skin) — Superior fit - [Dr. Dennis Gross Alpha Beta Universal Daily Peel](https://lovi.care/skincare/es/p/dr-dennis-gross/alpha-beta-universal-daily-peel/for/acne-prone-skin) — Superior fit — [€175.00 at Amazon](https://www.amazon.de/dp/B009QZ595Q?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [The Ordinary Lactic Acid 5% + HA](https://lovi.care/skincare/es/p/the-ordinary/lactic-acid-5-ha/for/dry-skin) — Superior fit - [Good Molecules Overnight Exfoliating Treatment](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [€20.99 at Amazon](https://www.amazon.de/dp/B08TMDRF1L?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) ### [Lactobionic acid](https://lovi.care/skincare/es/ingredients/lactobionic-acid) products - [Verb Ghost Exfoliating Scalp Nectar](https://lovi.care/skincare/es/p/verb/ghost-exfoliating-scalp-nectar/for/oily-skin) — Superior fit - [Elemis Pro-Collagen Marine Moisture Essence](https://lovi.care/skincare/es/p/elemis/pro-collagen-marine-moisture-essence/for/mature-skin) — Average fit — [€80.00 at Amazon](https://www.amazon.de/dp/B08RTFMJQ9?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Elemis Pro-Collagen Tri-Acid Peel](https://lovi.care/skincare/es/p/elemis/pro-collagen-tri-acid-peel/for/dark-spots) — High fit - [Skintific AHA BHA PHA LHA Peeling Solution](https://lovi.care/skincare/es/p/skintific/aha-bha-pha-lha-peeling-solution/for/oily-acne-prone-skin) — High fit - [Benton PHA Peeling Toner](https://lovi.care/skincare/es/p/benton/pha-peeling-toner/for/dark-spots) — Superior fit - [VT COSMETICS Cica Skin](https://lovi.care/skincare/es/p/vt-cosmetics/cica-skin/for/sensitive-skin) — Superior fit — [€24.98 at Amazon](https://www.amazon.de/dp/B0C2TSK62Y?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [Estée Lauder Perfectly Clean Multi-Action Toning Lotion/Refiner](https://lovi.care/skincare/es/p/estee-lauder/perfectly-clean-multi-action-toning-lotion-refiner/for/oily-skin) — High fit — [€23.74 at Amazon](https://www.amazon.de/dp/B00CAUJJM8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1) - [COSRX Full Fit Propolis Synergy Pad](https://lovi.care/skincare/es/p/cosrx/full-fit-propolis-synergy-pad/for/mature-skin) — High fit ## Questions and answers ### Can you use lactic acid and lactobionic acid together? Yes, you can use [lactic acid](https://lovi.care/skincare/es/ingredients/lactic-acid) and [lactobionic acid](https://lovi.care/skincare/es/ingredients/lactobionic-acid) together because they work well to provide gentle exfoliation and antioxidant protection, which is ideal for sensitive skin. You can find this combination in products like MZ Skin Radiance & Renewal Instant Clarity Refining Mask and MZ Skin Cleanse & Clarify Dual Action AHA Cleanser & Mask. ### Which goes first, lactic acid or lactobionic acid? Lactic acid and lactobionic acid work well together and can be used in products such as MZ Skin Radiance & Renewal Instant Clarity Refining Mask and MZ Skin Cleanse & Clarify Dual Action AHA Cleanser & Mask. ## Research on lactic acid and lactobionic acid - [Lactate triggers KAT8-mediated LTBP1 lactylation at lysine 752 to promote skin rejuvenation by inducing collagen synthesis in fibroblasts](https://pubmed.ncbi.nlm.nih.gov/39102921/) Lactic acid · International Journal of Biological Macromolecules, 2024 - [Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway](https://pubmed.ncbi.nlm.nih.gov/36575891/) Lactic acid · Journal of Cosmetic Dermatology, 2023 - [Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss](https://pubmed.ncbi.nlm.nih.gov/30661294/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019 - [Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?](https://pubmed.ncbi.nlm.nih.gov/11803256/) Lactic acid · Skin Pharmacology and Applied Skin Physiology, 2002 - [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010 - [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019 ## Other combinations - Keep them apart: [Benzoyl peroxide and lactic acid](https://lovi.care/skincare/es/ingredients/benzoyl-peroxide-and-lactic-acid) - Keep them apart: [Retinol and lactic acid](https://lovi.care/skincare/es/ingredients/retinol-and-lactic-acid) - Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-lactic-acid) - Work well together: [Lactic acid and sodium lactate](https://lovi.care/skincare/es/ingredients/lactic-acid-and-sodium-lactate) - Work well together: [Lactic acid and tromethamine](https://lovi.care/skincare/es/ingredients/lactic-acid-and-tromethamine) - Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-lactobionic-acid) - Work well together: [Hyaluronic acid and lactobionic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid-and-lactobionic-acid) - Work well together: [Lactic acid and betaine](https://lovi.care/skincare/es/ingredients/lactic-acid-and-betaine) - Work well together: [Glycerin and lactic acid](https://lovi.care/skincare/es/ingredients/glycerin-and-lactic-acid) - Depends on the strength: [Lactic acid and hyaluronic acid](https://lovi.care/skincare/es/ingredients/lactic-acid-and-hyaluronic-acid) - Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/es/ingredients/lactic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Bio-placenta peptides and lactic acid](https://lovi.care/skincare/es/ingredients/bio-placenta-peptides-and-lactic-acid) - Keep them apart: [Carnosine and lactic acid](https://lovi.care/skincare/es/ingredients/carnosine-and-lactic-acid) - Keep them apart: [Lactic acid and collagen peptide](https://lovi.care/skincare/es/ingredients/lactic-acid-and-collagen-peptide) - Keep them apart: [Lactic acid and copper peptide](https://lovi.care/skincare/es/ingredients/lactic-acid-and-copper-peptide) - Keep them apart: [Hexapeptide and lactic acid](https://lovi.care/skincare/es/ingredients/hexapeptide-and-lactic-acid) - Keep them apart: [Lactic acid and hexapeptide-9](https://lovi.care/skincare/es/ingredients/lactic-acid-and-hexapeptide-9) - Keep them apart: [Lactic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/es/ingredients/lactic-acid-and-palmitoyl-pentapeptide-4) - Keep them apart: [Lactic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/es/ingredients/lactic-acid-and-palmitoyl-tripeptide-1) - Keep them apart: [Lactic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/lactic-acid-and-peptide-rich-plasma) - Keep them apart: [Lactic acid and triple peptide blend](https://lovi.care/skincare/es/ingredients/lactic-acid-and-triple-peptide-blend) - Keep them apart: [Adapalene and lactic acid](https://lovi.care/skincare/es/ingredients/adapalene-and-lactic-acid) - Keep them apart: [Lactic acid and granactive retinoid](https://lovi.care/skincare/es/ingredients/lactic-acid-and-granactive-retinoid) - Keep them apart: [Lactic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/es/ingredients/lactic-acid-and-hydroxypinacolone-retinoate) - Keep them apart: [Pro-retinol and lactic acid](https://lovi.care/skincare/es/ingredients/pro-retinol-and-lactic-acid) - Keep them apart: [Retinal and lactic acid](https://lovi.care/skincare/es/ingredients/retinal-and-lactic-acid) - Keep them apart: [Lactic acid and retinoid blend](https://lovi.care/skincare/es/ingredients/lactic-acid-and-retinoid-blend) - Keep them apart: [Tretinoin and lactic acid](https://lovi.care/skincare/es/ingredients/tretinoin-and-lactic-acid) - Work well together: [AHA blend glycolic and citric acids and lactobionic acid](https://lovi.care/skincare/es/ingredients/aha-blend-glycolic-and-citric-acids-and-lactobionic-acid) - Work well together: [Lactobionic acid and citric acid](https://lovi.care/skincare/es/ingredients/lactobionic-acid-and-citric-acid) - Work well together: [Glycolic acid and lactobionic acid](https://lovi.care/skincare/es/ingredients/glycolic-acid-and-lactobionic-acid) - Work well together: [Lactic acid and gluconolactone](https://lovi.care/skincare/es/ingredients/lactic-acid-and-gluconolactone) - Work well together: [Mandelic acid and lactobionic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-lactobionic-acid) - Work well together: [Vitamin C and lactobionic acid](https://lovi.care/skincare/es/ingredients/vitamin-c-and-lactobionic-acid) - Work well together: [Lactic acid and cholesterol](https://lovi.care/skincare/es/ingredients/lactic-acid-and-cholesterol) - Work well together: [Lactic acid and lauric acid](https://lovi.care/skincare/es/ingredients/lactic-acid-and-lauric-acid) - Work well together: [Linoleic acid and lactic acid](https://lovi.care/skincare/es/ingredients/linoleic-acid-and-lactic-acid) - Keep them apart: [Lactic acid and tri-ceramide complex](https://lovi.care/skincare/es/ingredients/lactic-acid-and-tri-ceramide-complex) - Work well together: [Arginine and lactic acid](https://lovi.care/skincare/es/ingredients/arginine-and-lactic-acid) - Work well together: [Lactic acid and GABA](https://lovi.care/skincare/es/ingredients/lactic-acid-and-gaba) - Work well together: [Silk amino acids and lactic acid](https://lovi.care/skincare/es/ingredients/silk-amino-acids-and-lactic-acid) - Work well together: [Lactic acid and taurine](https://lovi.care/skincare/es/ingredients/lactic-acid-and-taurine) - Work well together: [Lactic acid and theanine](https://lovi.care/skincare/es/ingredients/lactic-acid-and-theanine) - Work well together: [Salicylic acid and lactobionic acid](https://lovi.care/skincare/es/ingredients/salicylic-acid-and-lactobionic-acid) - Work well together: [Ferulic acid and lactic acid](https://lovi.care/skincare/es/ingredients/ferulic-acid-and-lactic-acid) - Work well together: [Vitamin E and lactic acid](https://lovi.care/skincare/es/ingredients/vitamin-e-and-lactic-acid) - Keep them apart: [Azelaic acid and lactic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-lactic-acid) - Keep them apart: [Salicylic acid and lactic acid](https://lovi.care/skincare/es/ingredients/salicylic-acid-and-lactic-acid) - Work well together: [Allantoin and lactic acid](https://lovi.care/skincare/es/ingredients/allantoin-and-lactic-acid) - Work well together: [Lactic acid and bisabolol](https://lovi.care/skincare/es/ingredients/lactic-acid-and-bisabolol) - Work well together: [Panthenol and lactic acid](https://lovi.care/skincare/es/ingredients/panthenol-and-lactic-acid) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/lactic-acid-and-lactobionic-acid - United Kingdom: https://lovi.care/skincare/uk/ingredients/lactic-acid-and-lactobionic-acid - Ireland: https://lovi.care/skincare/ie/ingredients/lactic-acid-and-lactobionic-acid - Germany: https://lovi.care/skincare/de/ingredients/lactic-acid-and-lactobionic-acid - France: https://lovi.care/skincare/fr/ingredients/lactic-acid-and-lactobionic-acid - Italy: https://lovi.care/skincare/it/ingredients/lactic-acid-and-lactobionic-acid - Netherlands: https://lovi.care/skincare/nl/ingredients/lactic-acid-and-lactobionic-acid - Spain: https://lovi.care/skincare/es/ingredients/lactic-acid-and-lactobionic-acid (this page) - Canada: https://lovi.care/skincare/ca/ingredients/lactic-acid-and-lactobionic-acid - Australia: https://lovi.care/skincare/au/ingredients/lactic-acid-and-lactobionic-acid - Singapore: https://lovi.care/skincare/sg/ingredients/lactic-acid-and-lactobionic-acid - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/lactic-acid-and-lactobionic-acid - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/lactic-acid-and-lactobionic-acid