# Azelaic acid and peptide-rich plasma

Page: https://lovi.care/skincare/es/ingredients/azelaic-acid-and-peptide-rich-plasma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Keep them apart

Use them at different times of day, applying [azelaic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid) in the morning and peptides at night, because mixing them reduces their effectiveness. Acid products can break down peptides and stop them from working properly on your skin. To get the best results, use these ingredients in separate steps or at different times of day.

- [All about azelaic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid)
- [All about peptide-rich plasma](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma)

### [Azelaic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid) products

- [The Ordinary Azelaic Acid Suspension 10%](https://lovi.care/skincare/es/p/the-ordinary/azelaic-acid-suspension-10/for/acne-prone-skin) — High fit — [€10.90 at Amazon](https://www.amazon.de/dp/B0BBLZ2YBP?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Paula's Choice 10% Azelaic Acid Booster](https://lovi.care/skincare/es/p/paula-s-choice/10-azelaic-acid-booster/for/acne-prone-skin) — High fit — [€49.00 at Amazon](https://www.amazon.de/dp/B09S9R72XB?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Topicals Faded Serum](https://lovi.care/skincare/es/p/topicals/faded-serum/for/oily-acne-prone-skin) — Superior fit — [€8.99 at Amazon](https://www.amazon.de/dp/B0FT32CL2W?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [NATURIUM Azelaic Topical Acid 10%](https://lovi.care/skincare/es/p/naturium/azelaic-topical-acid-10/for/acne-prone-skin) — Superior fit
- [Musely The Spot Cream](https://lovi.care/skincare/es/p/musely/the-spot-cream/for/mature-skin) — High fit
- [Topicals Faded Brightening & Clearing Serum](https://lovi.care/skincare/es/p/topicals/faded-brightening-and-clearing-serum/for/acne-prone-skin) — High fit
- [Bioderma Pigmentbio Sensitive Areas](https://lovi.care/skincare/es/p/bioderma/pigmentbio-sensitive-areas/for/oily-acne-prone-skin) — High fit — [€21.08 at Amazon](https://www.amazon.de/dp/B07RPBDXHM?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Peach Slices Redness Relief Azelaic Acid Serum](https://lovi.care/skincare/es/p/peach-slices/redness-relief-azelaic-acid-serum/for/sensitive-skin) — High fit
- [Finacea Gel](https://lovi.care/skincare/es/p/finacea/gel/for/oily-acne-prone-skin) — High fit
- [NATURIUM Niacinamide Cleansing Gelée 3%](https://lovi.care/skincare/es/p/naturium/niacinamide-cleansing-gelee-3/for/acne-prone-skin) — High fit
- [NATURIUM Azelaic Acid Emulsion 10%](https://lovi.care/skincare/es/p/naturium/azelaic-acid-emulsion-10/for/acne-prone-skin) — High fit
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/es/p/strivectin/daily-reveal-exfoliating-pads/for/oily-skin) — Average fit — [€38.90 at Amazon](https://www.amazon.de/dp/B089TPYFX3?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### [Peptide-rich plasma](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma) products

- [Eighth Day Regenerative Serum](https://lovi.care/skincare/es/p/eighth-day/regenerative-serum/for/dry-sensitive-skin) — High fit

## Questions and answers

### Can you use azelaic acid and peptide-rich plasma together?

No, you should keep [azelaic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid) and [peptide-rich plasma](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma) apart because low-pH acids can break down peptide bonds and reduce their activity. Use them in separate steps or routines, such as applying one in the morning and the other at night.

### Which goes first, azelaic acid or peptide-rich plasma?

Keep azelaic acid and peptide-rich plasma apart by using them in separate routines, such as morning and night, because low-pH acids can reduce peptide activity.

### Are azelaic acid and peptide-rich plasma good for sensitive skin?

Keep azelaic acid and peptide-rich plasma apart by using them in separate routines to protect sensitive skin. Combining them directly is not recommended because low-pH acids may hydrolyze peptide bonds and reduce activity.

## Research on azelaic acid and peptide-rich plasma

- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023

## Other combinations

- Keep them apart: [Adapalene and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/adapalene-and-peptide-rich-plasma)
- Keep them apart: [Granactive retinoid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/granactive-retinoid-and-peptide-rich-plasma)
- Keep them apart: [Hydroxypinacolone retinoate and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/hydroxypinacolone-retinoate-and-peptide-rich-plasma)
- Keep them apart: [Pro-retinol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/pro-retinol-and-peptide-rich-plasma)
- Keep them apart: [Retinal and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/retinal-and-peptide-rich-plasma)
- Keep them apart: [Retinoid blend and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/retinoid-blend-and-peptide-rich-plasma)
- Depends on the strength: [Retinol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/retinol-and-peptide-rich-plasma)
- Keep them apart: [Tretinoin and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/tretinoin-and-peptide-rich-plasma)
- Keep them apart: [Vitamin A and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/vitamin-a-and-peptide-rich-plasma)
- Work well together: [Liposome and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/liposome-and-peptide-rich-plasma)
- Work well together: [Microcapsule and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/microcapsule-and-peptide-rich-plasma)
- Keep them apart: [Vitamin C and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/vitamin-c-and-peptide-rich-plasma)
- Work well together: [Betaine and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/betaine-and-peptide-rich-plasma)
- Work well together: [Glycerin and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/glycerin-and-peptide-rich-plasma)
- Work well together: [Hyaluronic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/hyaluronic-acid-and-peptide-rich-plasma)
- Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/niacinamide-and-peptide-rich-plasma)
- Work well together: [Panthenol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/panthenol-and-peptide-rich-plasma)
- Work well together: [Bakuchiol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/bakuchiol-and-peptide-rich-plasma)
- Keep them apart: [Azelaic acid and hyaluronic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-hyaluronic-acid)
- Work well together: [Arginine and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/arginine-and-peptide-rich-plasma)
- Work well together: [Peptide-rich plasma and GABA](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-gaba)
- Work well together: [Silk amino acids and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/silk-amino-acids-and-peptide-rich-plasma)
- Work well together: [Taurine and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/taurine-and-peptide-rich-plasma)
- Work well together: [Peptide-rich plasma and theanine](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/aha-blend-glycolic-and-citric-acids-and-peptide-rich-plasma)
- Keep them apart: [Citric acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/citric-acid-and-peptide-rich-plasma)
- Keep them apart: [Glycolic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/glycolic-acid-and-peptide-rich-plasma)
- Keep them apart: [Lactic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/lactic-acid-and-peptide-rich-plasma)
- Keep them apart: [Mandelic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-peptide-rich-plasma)
- Work well together: [Coenzyme Q10 and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/coenzyme-q10-and-peptide-rich-plasma)
- Work well together: [Green tea and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/green-tea-and-peptide-rich-plasma)
- Work well together: [Vitamin E and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/vitamin-e-and-peptide-rich-plasma)
- Work well together: [Beta-sitosterol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/beta-sitosterol-and-peptide-rich-plasma)
- Work well together: [Ceramide-building complex and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/ceramide-building-complex-and-peptide-rich-plasma)
- Work well together: [Cholesterol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/cholesterol-and-peptide-rich-plasma)
- Work well together: [Phytosphingosine and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/phytosphingosine-and-peptide-rich-plasma)
- Work well together: [Phytosterol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/phytosterol-and-peptide-rich-plasma)
- Work well together: [Peptide-rich plasma and squalene](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-squalene)
- Work well together: [Peptide-rich plasma and tri-ceramide complex](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/salicylic-acid-and-peptide-rich-plasma)
- Keep them apart: [Peptide-rich plasma and baking soda](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-baking-soda)
- Keep them apart: [Bleach and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/bleach-and-peptide-rich-plasma)
- Keep them apart: [Potassium hydroxide and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/potassium-hydroxide-and-peptide-rich-plasma)
- Keep them apart: [Peptide-rich plasma and behenyl alcohol](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-behenyl-alcohol)
- Keep them apart: [Isopropyl alcohol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/isopropyl-alcohol-and-peptide-rich-plasma)
- Keep them apart: [Polyvinyl alcohol and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/polyvinyl-alcohol-and-peptide-rich-plasma)
- Keep them apart: [Copper and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/copper-and-peptide-rich-plasma)
- Keep them apart: [Azelaic acid and aha blend glycolic and citric acids](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-aha-blend-glycolic-and-citric-acids)
- Keep them apart: [Azelaic acid and citric acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-citric-acid)
- Keep them apart: [Glycolic acid and azelaic acid](https://lovi.care/skincare/es/ingredients/glycolic-acid-and-azelaic-acid)
- Keep them apart: [Azelaic acid and lactic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-lactic-acid)
- Keep them apart: [Azelaic acid and mandelic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-mandelic-acid)
- Keep them apart: [Azelaic acid and salicylic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-salicylic-acid)
- Keep them apart: [Magnesium and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/magnesium-and-peptide-rich-plasma)
- Keep them apart: [Zinc and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/zinc-and-peptide-rich-plasma)
- Keep them apart: [Zinc sulfate and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/zinc-sulfate-and-peptide-rich-plasma)
- Keep them apart: [Benzoyl peroxide and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/benzoyl-peroxide-and-peptide-rich-plasma)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and bio-placenta peptides](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-bio-placenta-peptides)
- Keep them apart: [Azelaic acid and collagen peptide](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-collagen-peptide)
- Keep them apart: [Azelaic acid and copper peptide](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-copper-peptide)
- Keep them apart: [Azelaic acid and hexapeptide](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-hexapeptide)
- Keep them apart: [Azelaic acid and hexapeptide-9](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-hexapeptide-9)
- Keep them apart: [Azelaic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Azelaic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Azelaic acid and triple peptide blend](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-triple-peptide-blend)
- Keep them apart: [Peptide-rich plasma and protease](https://lovi.care/skincare/es/ingredients/peptide-rich-plasma-and-protease)
- Keep them apart: [Superoxide dismutase and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/superoxide-dismutase-and-peptide-rich-plasma)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/azelaic-acid-and-peptide-rich-plasma
- United Kingdom: https://lovi.care/skincare/uk/ingredients/azelaic-acid-and-peptide-rich-plasma
- Ireland: https://lovi.care/skincare/ie/ingredients/azelaic-acid-and-peptide-rich-plasma
- Germany: https://lovi.care/skincare/de/ingredients/azelaic-acid-and-peptide-rich-plasma
- France: https://lovi.care/skincare/fr/ingredients/azelaic-acid-and-peptide-rich-plasma
- Italy: https://lovi.care/skincare/it/ingredients/azelaic-acid-and-peptide-rich-plasma
- Netherlands: https://lovi.care/skincare/nl/ingredients/azelaic-acid-and-peptide-rich-plasma
- Spain: https://lovi.care/skincare/es/ingredients/azelaic-acid-and-peptide-rich-plasma (this page)
- Canada: https://lovi.care/skincare/ca/ingredients/azelaic-acid-and-peptide-rich-plasma
- Australia: https://lovi.care/skincare/au/ingredients/azelaic-acid-and-peptide-rich-plasma
- Singapore: https://lovi.care/skincare/sg/ingredients/azelaic-acid-and-peptide-rich-plasma
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/azelaic-acid-and-peptide-rich-plasma
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/azelaic-acid-and-peptide-rich-plasma