# Arginine and mandelic acid

Page: https://lovi.care/skincare/es/ingredients/arginine-and-mandelic-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Work well together

Use them together by applying [mandelic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid) first and [arginine](https://lovi.care/skincare/es/ingredients/arginine) second to keep skin hydrated and balanced. Mandelic acid gently exfoliates while arginine keeps skin comfortable and properly hydrated. If skin feels sensitive, try a gentler strength or space out the applications.

- [All about arginine](https://lovi.care/skincare/es/ingredients/arginine)
- [All about mandelic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid)

### [Arginine](https://lovi.care/skincare/es/ingredients/arginine) products

- [SKIN AQUA UV Super Moisture Gel](https://lovi.care/skincare/es/p/skin-aqua/uv-super-moisture-gel/for/oily-skin) — Superior fit
- [SKIN AQUA UV Super Moisture Milk](https://lovi.care/skincare/es/p/skin-aqua/uv-super-moisture-milk/for/dark-spots) — High fit
- [NIOD Superoxide Dismutase Saccharide Mist](https://lovi.care/skincare/es/p/niod/superoxide-dismutase-saccharide-mist/for/dry-sensitive-skin) — Average fit
- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/es/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-acne-prone-skin) — Superior fit — [€6.30 at Notino](https://www.notino.es/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97-serum-hidratante-intensivo-con-acido-hialuronico/p-16191539/)
- [S.Nature Aqua Squalane Moisturizing Cream](https://lovi.care/skincare/es/p/s-nature/aqua-squalane-moisturizing-cream/for/dry-skin) — Superior fit — [€19.30 at Amazon](https://www.amazon.de/dp/B09KV5LCVH?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

### [Mandelic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid) products

- [The Ordinary Mandelic Acid 10% + HA](https://lovi.care/skincare/es/p/the-ordinary/mandelic-acid-10-ha/for/acne-prone-skin) — Superior fit — [€8.00 at Amazon](https://www.amazon.de/dp/B07BGJMNYL?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Nécessaire The Body Retinol](https://lovi.care/skincare/es/p/necessaire/the-body-retinol/for/dark-spots) — Average fit
- [Good Molecules Mandelic Acid Serum](https://lovi.care/skincare/es/p/good-molecules/mandelic-acid-serum/for/dry-sensitive-skin) — Superior fit
- [Glamglow Supermud Clearing Treatment](https://lovi.care/skincare/es/p/glamglow/supermud-clearing-treatment/for/oily-skin) — High fit
- [Dermalogica PowerBright Dark Spot Peel](https://lovi.care/skincare/es/p/dermalogica/powerbright-dark-spot-peel/for/oily-skin) — Average fit
- [Sofie Pavitt Face Mandelic Clearing Serum](https://lovi.care/skincare/es/p/sofie-pavitt-face/mandelic-clearing-serum/for/oily-acne-prone-skin) — High fit
- [Cetaphil Gentle Exfoliating SA Lotion](https://lovi.care/skincare/es/p/cetaphil/gentle-exfoliating-sa-lotion/for/combination-skin) — High fit — [€15.59 at Amazon](https://www.amazon.de/dp/B0FFMYS55N?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Cell Cycle Catalyst](https://lovi.care/skincare/es/p/skinceuticals/cell-cycle-catalyst/for/oily-acne-prone-skin) — Average fit
- [DIME TBT Serum](https://lovi.care/skincare/es/p/dime/tbt-serum/for/dry-sensitive-skin) — High fit
- [By Wishtrend Mandelic Acid 5% Skin Prep Water](https://lovi.care/skincare/es/p/by-wishtrend/mandelic-acid-5-skin-prep-water/for/acne-prone-skin) — High fit — [€21.30 at Amazon](https://www.amazon.de/dp/B07MC4P4R8?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Haruharu Wonder Black Rice Triple AHA Gentle Cleansing Gel](https://lovi.care/skincare/es/p/haruharu-wonder/black-rice-triple-aha-gentle-cleansing-gel/for/oily-acne-prone-skin) — High fit — [€14.58 at Amazon](https://www.amazon.de/dp/B0CKVL9PGY?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/es/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit

## Questions and answers

### Can you use arginine and mandelic acid together?

Yes, you can use [arginine](https://lovi.care/skincare/es/ingredients/arginine) and [mandelic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid) together because they combine to strengthen your skin's hydration matrix and buffering capacity. You can use them daily in mild exfoliants or balancing toners, and Lovi rates this combination as High.

### Which goes first, arginine or mandelic acid?

Arginine and mandelic acid work well together in mild daily exfoliants or balancing toners to strengthen the skin's hydration matrix and maintain osmotic balance.

### Are arginine and mandelic acid good for sensitive skin?

Yes, arginine and mandelic acid work well together to strengthen your skin’s hydration matrix and maintain osmotic balance. You can use this combination in mild daily exfoliants or balancing toners for normal to dry, sensitive skin.

## Research on arginine and mandelic acid

- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Arginine · International Journal of Molecular Sciences, 2024
- [A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects](https://pubmed.ncbi.nlm.nih.gov/31347768/) Arginine · Journal of Cosmetic Dermatology, 2020

## Other combinations

- Keep them apart: [Benzoyl peroxide and mandelic acid](https://lovi.care/skincare/es/ingredients/benzoyl-peroxide-and-mandelic-acid)
- Keep them apart: [Retinol and mandelic acid](https://lovi.care/skincare/es/ingredients/retinol-and-mandelic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/es/ingredients/niacinamide-and-mandelic-acid)
- Work well together: [Mandelic acid and sodium lactate](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-sodium-lactate)
- Work well together: [Mandelic acid and tromethamine](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-tromethamine)
- Work well together: [Mandelic acid and betaine](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-betaine)
- Work well together: [Glycerin and mandelic acid](https://lovi.care/skincare/es/ingredients/glycerin-and-mandelic-acid)
- Depends on the strength: [Mandelic acid and hyaluronic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-hyaluronic-acid)
- Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/es/ingredients/arginine-and-acetyl-hexapeptide-3)
- Work well together: [Bio-placenta peptides and arginine](https://lovi.care/skincare/es/ingredients/bio-placenta-peptides-and-arginine)
- Work well together: [Arginine and collagen peptide](https://lovi.care/skincare/es/ingredients/arginine-and-collagen-peptide)
- Work well together: [Arginine and copper peptide](https://lovi.care/skincare/es/ingredients/arginine-and-copper-peptide)
- Work well together: [Hexapeptide and arginine](https://lovi.care/skincare/es/ingredients/hexapeptide-and-arginine)
- Work well together: [Arginine and hexapeptide-9](https://lovi.care/skincare/es/ingredients/arginine-and-hexapeptide-9)
- Work well together: [Arginine and palmitoyl pentapeptide-4](https://lovi.care/skincare/es/ingredients/arginine-and-palmitoyl-pentapeptide-4)
- Work well together: [Arginine and palmitoyl tripeptide-1](https://lovi.care/skincare/es/ingredients/arginine-and-palmitoyl-tripeptide-1)
- Work well together: [Arginine and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/arginine-and-peptide-rich-plasma)
- Work well together: [Arginine and triple peptide blend](https://lovi.care/skincare/es/ingredients/arginine-and-triple-peptide-blend)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/es/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Keep them apart: [Bio-placenta peptides and mandelic acid](https://lovi.care/skincare/es/ingredients/bio-placenta-peptides-and-mandelic-acid)
- Keep them apart: [Carnosine and mandelic acid](https://lovi.care/skincare/es/ingredients/carnosine-and-mandelic-acid)
- Keep them apart: [Mandelic acid and collagen peptide](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-collagen-peptide)
- Keep them apart: [Mandelic acid and copper peptide](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-copper-peptide)
- Keep them apart: [Hexapeptide and mandelic acid](https://lovi.care/skincare/es/ingredients/hexapeptide-and-mandelic-acid)
- Keep them apart: [Mandelic acid and hexapeptide-9](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-hexapeptide-9)
- Keep them apart: [Mandelic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Mandelic acid and palmitoyl tripeptide-1](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Mandelic acid and peptide-rich plasma](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-peptide-rich-plasma)
- Keep them apart: [Mandelic acid and triple peptide blend](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-triple-peptide-blend)
- Keep them apart: [Adapalene and mandelic acid](https://lovi.care/skincare/es/ingredients/adapalene-and-mandelic-acid)
- Keep them apart: [Mandelic acid and granactive retinoid](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-granactive-retinoid)
- Keep them apart: [Mandelic acid and hydroxypinacolone retinoate](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and mandelic acid](https://lovi.care/skincare/es/ingredients/pro-retinol-and-mandelic-acid)
- Keep them apart: [Retinal and mandelic acid](https://lovi.care/skincare/es/ingredients/retinal-and-mandelic-acid)
- Keep them apart: [Mandelic acid and retinoid blend](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-retinoid-blend)
- Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/es/ingredients/tretinoin-and-mandelic-acid)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Mandelic acid and lactobionic acid](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-lactobionic-acid)
- Work well together: [Mandelic acid and cholesterol](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-cholesterol)
- Work well together: [Mandelic acid and lauric acid](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-lauric-acid)
- Work well together: [Linoleic acid and mandelic acid](https://lovi.care/skincare/es/ingredients/linoleic-acid-and-mandelic-acid)
- Keep them apart: [Mandelic acid and tri-ceramide complex](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-tri-ceramide-complex)
- Work well together: [AHA blend glycolic and citric acids and arginine](https://lovi.care/skincare/es/ingredients/aha-blend-glycolic-and-citric-acids-and-arginine)
- Work well together: [Arginine and citric acid](https://lovi.care/skincare/es/ingredients/arginine-and-citric-acid)
- Work well together: [Glycolic acid and arginine](https://lovi.care/skincare/es/ingredients/glycolic-acid-and-arginine)
- Work well together: [Arginine and lactic acid](https://lovi.care/skincare/es/ingredients/arginine-and-lactic-acid)
- Work well together: [Mandelic acid and GABA](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-gaba)
- Work well together: [Silk amino acids and mandelic acid](https://lovi.care/skincare/es/ingredients/silk-amino-acids-and-mandelic-acid)
- Work well together: [Taurine and mandelic acid](https://lovi.care/skincare/es/ingredients/taurine-and-mandelic-acid)
- Work well together: [Mandelic acid and theanine](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-theanine)
- Work well together: [Ferulic acid and mandelic acid](https://lovi.care/skincare/es/ingredients/ferulic-acid-and-mandelic-acid)
- Work well together: [Vitamin E and mandelic acid](https://lovi.care/skincare/es/ingredients/vitamin-e-and-mandelic-acid)
- Keep them apart: [Azelaic acid and mandelic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid-and-mandelic-acid)
- Keep them apart: [Salicylic acid and mandelic acid](https://lovi.care/skincare/es/ingredients/salicylic-acid-and-mandelic-acid)
- Work well together: [Arginine and hyaluronic acid](https://lovi.care/skincare/es/ingredients/arginine-and-hyaluronic-acid)
- Work well together: [Allantoin and mandelic acid](https://lovi.care/skincare/es/ingredients/allantoin-and-mandelic-acid)
- Work well together: [Mandelic acid and bisabolol](https://lovi.care/skincare/es/ingredients/mandelic-acid-and-bisabolol)
- Work well together: [Panthenol and mandelic acid](https://lovi.care/skincare/es/ingredients/panthenol-and-mandelic-acid)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/arginine-and-mandelic-acid
- United Kingdom: https://lovi.care/skincare/uk/ingredients/arginine-and-mandelic-acid
- Ireland: https://lovi.care/skincare/ie/ingredients/arginine-and-mandelic-acid
- Germany: https://lovi.care/skincare/de/ingredients/arginine-and-mandelic-acid
- France: https://lovi.care/skincare/fr/ingredients/arginine-and-mandelic-acid
- Italy: https://lovi.care/skincare/it/ingredients/arginine-and-mandelic-acid
- Netherlands: https://lovi.care/skincare/nl/ingredients/arginine-and-mandelic-acid
- Spain: https://lovi.care/skincare/es/ingredients/arginine-and-mandelic-acid (this page)
- Canada: https://lovi.care/skincare/ca/ingredients/arginine-and-mandelic-acid
- Australia: https://lovi.care/skincare/au/ingredients/arginine-and-mandelic-acid
- Singapore: https://lovi.care/skincare/sg/ingredients/arginine-and-mandelic-acid
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/arginine-and-mandelic-acid
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/arginine-and-mandelic-acid