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Arginine and hexapeptide-9

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Arginine and hexapeptide-9: work well together

Work well together

Use them together in the same routine, applying the amino acid first and the peptide right after. Arginine helps deliver moisture and nourishment, while hexapeptide-9 supports firmer, healthier-looking skin. You can continue using both together, but if your skin feels sensitive, try applying them on alternate nights or look for gentler formulas.

Arginine products

Hexapeptide-9 products

Questions and answers

Can you use arginine and hexapeptide-9 together?

Yes, you can use arginine and hexapeptide-9 together because they support structural protein synthesis and moisture balance, making them beneficial when paired in hydrating and reparative complexes for all skin types.

Journal of Cosmetic Dermatology, 2025

Which goes first, arginine or hexapeptide-9?

Arginine and hexapeptide-9 work well together to support structural protein synthesis and moisture balance, so you can use them in hydrating and reparative complexes for all skin types.

Are arginine and hexapeptide-9 good for sensitive skin?

Arginine and hexapeptide-9 work well together to support structural protein synthesis and moisture balance for all skin types. Lovi gives this combination a High fit.

Research on arginine and hexapeptide-9

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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