# SK-II vs Theramid

Page: https://lovi.care/skincare/es/compare/sk-ii-vs-theramid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

SK-II and Theramid are distinguished skincare brands that offer luxurious moisturizers, potent [serums](https://lovi.care/skincare/es/ingredients/serum), rejuvenating masks, and clarifying toners. The former is known for formulas powered by its signature ingredient, pitera, while the latter is cherished for advanced treatments that rely on meticulously engineered compositions. Both brands suit a wide range of complexions, including combination, oily, normal, dry, and sensitive skin types. They differ primarily in their origin and approach, as the Japanese pioneer utilizes botanical science to improve pores and redness, whereas the Spanish newcomer delivers specialized active ingredients with remarkable precision and care.

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

Theramid is a Spanish skincare brand founded in 2022 and owned by Cosnova Group since 2026.

[cosmeticsbusiness.com](https://cosmeticsbusiness.com/cosnova-acquires-niche-beauty-labs-expand-skin-care)

This page compares some of the most popular SK-II and Theramid products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg12f05e0f0f).

### Popular SK-II vs Theramid products

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/es/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit
- [Facial Treatment Mask](https://lovi.care/skincare/es/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/es/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit
- [Skinpower Advanced Cream](https://lovi.care/skincare/es/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit
- [Genoptics Ultraura Essence](https://lovi.care/skincare/es/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/es/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit
- [Genoptics Spot Essence](https://lovi.care/skincare/es/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

#### Theramid

- [Copper Peptide](https://lovi.care/skincare/es/p/theramid/copper-peptide/for/oily-skin) — High fit
- [DERMA-PEPTIDES](https://lovi.care/skincare/es/p/theramid/derma-peptides/for/mature-skin) — High fit
- [Ceramide Treatment](https://lovi.care/skincare/es/p/theramid/ceramide-treatment/for/dry-sensitive-skin) — Superior fit

## People Say

SK-II

Theramid

- Improves texture and smoothness Mostly Mentioned Mostly Mentioned “skin feels soft as butter — SK-II Facial Treatment Essence” “pores became miraculously invisible — SK-II Facial Treatment Mask” “the texture is a sophisticated, lightweight gel that absorbs almost instantly without leaving a sticky residue — Theramid Copper Peptide” “Absorbs quickly — Theramid DERMA-PEPTIDES”
- Radiance and glow Mostly Mentioned Sometimes Noted “gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask” “Skin looks brighter — SK-II Genoptics Spot Essence” “instantly gives the skin a radiant glow and freshness — Theramid Copper Peptide”
- Balances and hydrates Mostly Mentioned Often Mentioned “flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream” “balanced my oily T-zone — SK-II Facial Treatment Essence” “Provides long-lasting hydration — Theramid Ceramide Treatment”
- Visible anti-aging Rarely Noted Mostly Mentioned “Fine lines are less visible — Theramid DERMA-PEPTIDES” “my skin feels incredibly fed and plump — Theramid Copper Peptide” “reducing the appearance of fine lines — SK-II Skinpower Advanced Cream”
- Gentle and non-irritating formulation Not noted Often Mentioned “Suitable for sensitive skin — Theramid DERMA-PEPTIDES” “incredibly gentle... I experienced zero redness or irritation — Theramid Copper Peptide”
- Lightweight absorption and feel Often Mentioned Not noted “drinks right into the skin — SK-II Facial Treatment Essence” “Leaves skin soft, feels moisturized, does not dry out skin. — SK-II Facial Treatment Cleansing Oil” “Watery consistency — SK-II Facial Treatment Clear Lotion”
- High price Mostly Mentioned Not noted “way too expensive — SK-II Facial Treatment Essence”
- Lack of results Often Mentioned Sometimes Noted “Nearly 2 months in, no result — Theramid Copper Peptide” “Overhyped by influencers — Theramid DERMA-PEPTIDES” “did absolutely nothing — SK-II Facial Treatment Essence”
- Unpleasant scent or fragrance Often Mentioned Rarely Noted “Didn't like the scent — Theramid Ceramide Treatment” “smells like dirty feet — SK-II Facial Treatment Essence”

## Questions and answers

### SK-II or Theramid: which is better?

SK-II and Theramid each excel in different areas, with SK-II winning on radiance, balance, and lightweight feel while Theramid offers more visible anti-aging results and a gentler formulation. When choosing between them, the products on this page help improve texture and smoothness equally.

### What is the difference between SK-II and Theramid?

SK-II helps provide better radiance and lightweight hydration, while Theramid may offer more visible anti-aging benefits and gentler soothing options according to reviewers. The products on this page from both brands list no fragrance.

### SK-II or Theramid: which moisturizer is better?

When it comes to moisturizers, SK-II and Theramid both offer strong options on this page, but they suit different needs. SK-II products like the Skinpower Advanced Cream feature High fits across mature and dry skin, while Theramid is noted for its restorative, soothing moisturizers like the Ceramide Treatment, which achieves a Superior fit for dry sensitive skin.

### Which is more affordable, SK-II or Theramid?

Theramid is often mentioned as having a high price, while SK-II is not highlighted on this page for being more affordable.

### Which causes fewer breakouts, SK-II or Theramid?

SK-II tends to cause fewer breakouts for acne-prone skin, as the products on this page generally achieve higher Lovi fit ratings for oily and acne-prone skin types compared to Theramid.

### Which brand has been established longer, SK-II or Theramid?

SK-II has been established longer, having been founded in Japan in 1980, whereas Theramid was founded in Spain in 2022.

### Do either SK-II or Theramid products contain fragrance?

Every product on this page for both SK-II and Theramid lists no fragrance in its ingredients.

### Which brand performs better for visible anti-aging according to review themes?

Theramid performs better for visible anti-aging according to review themes.

## Research behind their key ingredients

- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Madecassic acid · Indian Journal of Pharmaceutical Sciences, 2016
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Madecassic acid · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassic acid · Journal of Alternative and Complementary Medicine, 2020
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica · Molecules, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- [Positive and ecobiological contribution in skin photoprotection of ectoine and mannitol combined in vivo with UV filters](https://pubmed.ncbi.nlm.nih.gov/37539499/) Ectoin · Journal of Cosmetic Dermatology, 2024
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Copper tripeptide-1 · Skin Research and Technology, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026

## The brands

- Japanese skincare: [SK-II](https://lovi.care/skincare/es/brands/sk-ii)
- Spanish skincare: [Theramid](https://lovi.care/skincare/es/brands/theramid)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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