# Simple vs Natura Bissé

Page: https://lovi.care/skincare/es/compare/simple-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Simple and Natura Bissé are distinct skincare brands founded in Britain and Spain respectively, catering to different complexions through specialized formulations. Simple offers gentle moisturizers, makeup removers, cleansers, and toners featuring [niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide) and [glycerin](https://lovi.care/skincare/es/ingredients/glycerin) that suit oily skin and acne-prone skin best, including products like the Kind to Skin Soothing Facial Toner, the Micellar Cleansing [Water](https://lovi.care/skincare/es/ingredients/water), and the standard Micellar Water. Meanwhile, Natura Bissé provides luxurious moisturizers and advanced formulas, such as the Diamond Extreme, that suit mature, dry, and sensitive skin best with rich nourishing properties. Ultimately, both brands differ as the British brand focuses on accessible, ingredient-focused daily care, while the Spanish brand delivers high-end restorative treatments.

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Simple and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg74f75c7b65).

### Popular Simple vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/es/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [€266.00 at Amazon](https://www.amazon.de/dp/B0BKLRMKZV?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/es/p/simple/micellar-water/for/mature-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/es/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/es/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [€9.99 at Amazon](https://www.amazon.de/dp/B000LQX6XG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/es/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [€14.98 at Amazon](https://www.amazon.de/dp/B000LQUA6M?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/es/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B014G4ZW1M?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/es/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [€26.26 at Amazon](https://www.amazon.de/dp/B0787G22XC?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/es/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [€9.93 at Amazon](https://www.amazon.de/dp/B076V2D94Y?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Simple or Natura Bissé: which is better?

Simple is a better fit for value-friendly and gentle daily cleansing, featuring fragrance-free options and key ingredients like [glycerin](https://lovi.care/skincare/es/ingredients/glycerin) that help hydrate the skin. Lovi gives Simple a High fit for sensitive skin on its micellar [waters](https://lovi.care/skincare/es/ingredients/water) and a Superior fit for mature skin on its soothing facial toner. Meanwhile, Natura Bissé offers high-end anti-aging care such as Diamond Extreme, though it contains fragrance and is less suited for oily skin.

[Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What is the difference between Simple and Natura Bissé?

Simple offers budget-friendly, fragrance-free basics like gentle makeup removers and lightweight moisturizers, while Natura Bissé features luxury skincare such as its Diamond Extreme cream, which contains fragrance. Glycerin helps both brands provide daily hydration, and [niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide) in Simple products helps reduce skin pigmentation.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Simple or Natura Bissé: which moisturizer is better?

Simple offers several lightweight, value-friendly moisturizers, while Natura Bissé provides the Diamond Extreme moisturizer which achieves a Superior Lovi fit level for mature skin. Glycerin helps provide hydration across Simple products, and niacinamide helps control skin aging and pigmentation.

[Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which is more affordable, Simple or Natura Bissé?

Simple is more affordable, offering value-friendly moisturizers across the products on this page. Niacinamide helps improve skin appearance.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which causes fewer breakouts, Simple or Natura Bissé?

Simple features fragrance-free products on this page and includes niacinamide and glycerin, but reviewers note that the products on this page may sometimes cause breakouts or irritations.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which brand was founded earlier and in which country, Simple or Natura Bissé?

Simple was founded earlier in 1960 in the United Kingdom, whereas Natura Bissé was founded in 1979 in Spain.

### Do Simple products or Natura Bissé products contain fragrance?

Simple products on this page list no fragrance in their ingredients, whereas Natura Bissé includes fragrance in its products.

### Which skin types does the Simple brand fit best according to its routines?

According to its brand-focused routines, the Simple brand fits oily skin, acne-prone skin, and mature skin best.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- British skincare: [Simple](https://lovi.care/skincare/es/brands/simple)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/es/brands/natura-bisse)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/simple-vs-natura-bisse
- United Kingdom: https://lovi.care/skincare/uk/compare/simple-vs-natura-bisse
- Ireland: https://lovi.care/skincare/ie/compare/simple-vs-natura-bisse
- Germany: https://lovi.care/skincare/de/compare/simple-vs-natura-bisse
- France: https://lovi.care/skincare/fr/compare/simple-vs-natura-bisse
- Italy: https://lovi.care/skincare/it/compare/simple-vs-natura-bisse
- Netherlands: https://lovi.care/skincare/nl/compare/simple-vs-natura-bisse
- Spain: https://lovi.care/skincare/es/compare/simple-vs-natura-bisse (this page)
- Canada: https://lovi.care/skincare/ca/compare/simple-vs-natura-bisse
- Australia: https://lovi.care/skincare/au/compare/simple-vs-natura-bisse
- Singapore: https://lovi.care/skincare/sg/compare/simple-vs-natura-bisse
- Saudi Arabia: https://lovi.care/skincare/sa/compare/simple-vs-natura-bisse
- United Arab Emirates: https://lovi.care/skincare/ae/compare/simple-vs-natura-bisse