# Shiseido vs MAC

Page: https://lovi.care/skincare/es/compare/shiseido-vs-mac

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Shiseido and MAC are distinguished skincare brands that offer thoughtful arrays of daily essentials. Shiseido is beloved for its moisturizers, cleansers, sunscreens, and [serums](https://lovi.care/skincare/es/ingredients/serum) formulated with [glycerin](https://lovi.care/skincare/es/ingredients/glycerin), suiting sensitive and mature skin best. MAC is known for its reliable moisturizers and makeup removers crafted from balanced formulas, supporting balanced skin. While both provide gentle and effective care, they differ in their heritage, ownership, and targeted formulations for specific skin types.

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

[corp.shiseido.com](https://corp.shiseido.com/en/company/info/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [marketscreener.com](https://www.marketscreener.com/quote/stock/SHISEIDO-COMPANY-LIMITED-6492328/news/Shiseido-Company-Limited-Announces-CEO-Changes-Effective-January-1-2025-47501230/)

MAC is a Canadian skincare brand founded in 1984 and owned by The Estée Lauder Companies Inc. since 1994.

[elcompanies.com](https://www.elcompanies.com/en-gb/our-brands/mac) [en.wikipedia.org](https://en.wikipedia.org/wiki/Est%C3%A9e_Lauder_Companies)

This page compares some of the most popular Shiseido and MAC products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg9a71f4a2f8).

### Popular Shiseido vs MAC products

#### MAC

- [Hyper Real Serumizer](https://lovi.care/skincare/es/p/mac/hyper-real-serumizer/for/dry-sensitive-skin) — High fit — [€55.20 at Lookfantastic](https://www.lookfantastic.es/p/mac-hyper-real-serumizertm-skin-balancing-hydration-serum-30ml/14194687/)
- [Mineralize Timecheck Lotion](https://lovi.care/skincare/es/p/mac/mineralize-timecheck-lotion/for/dry-skin) — High fit
- [Hyper Real Fresh Canvas Cleansing Oil](https://lovi.care/skincare/es/p/mac/hyper-real-fresh-canvas-cleansing-oil/for/dry-sensitive-skin) — High fit

#### Shiseido

- [Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/es/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit — [€43.69 at Amazon](https://www.amazon.de/dp/B07XWL3TJ6?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/es/p/shiseido/ultimune-power-infusing-concentrate/for/sensitive-skin) — Average fit — [€57.45 at Amazon](https://www.amazon.de/dp/B0F5YYYNGW?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [VITAL PERFECTION](https://lovi.care/skincare/es/p/shiseido/vital-perfection/for/mature-skin) — Average fit — [€65.01 at Amazon](https://www.amazon.de/dp/B0CP67VGG7?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Clarifying Cleansing Foam](https://lovi.care/skincare/es/p/shiseido/clarifying-cleansing-foam/for/mature-skin) — Average fit — [€29.63 at Amazon](https://www.amazon.de/dp/B0HD83216K?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Essential Energy Hydrating Cream](https://lovi.care/skincare/es/p/shiseido/essential-energy-hydrating-cream/for/mature-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B09SBSPXTY?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Activating Essence](https://lovi.care/skincare/es/p/shiseido/activating-essence/for/dry-skin) — High fit
- [FUTURE SOLUTION LX](https://lovi.care/skincare/es/p/shiseido/future-solution-lx/for/sensitive-skin) — High fit
- [Bio-Performance Advanced Super Revitalizing Cream](https://lovi.care/skincare/es/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin) — Warning fit — [€57.79 at Amazon](https://www.amazon.de/dp/B00ASQ8H9C?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## People Say

Shiseido

MAC

- Deep hydration Mostly Mentioned Not noted “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Lightweight, silky, non-sticky, sinks in instantly. — Shiseido Ultimune Power Infusing Concentrate” “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION”
- Makeup base compatibility Rarely Noted Mostly Mentioned “foundation glides on — MAC Hyper Real Serumizer” “Sits beautifully under makeup — MAC Mineralize Timecheck Lotion” “Reduces appearance of pores — MAC Mineralize Timecheck Lotion” “Great base for makeup — Shiseido Essential Energy Hydrating Cream”
- Luxurious texture Mostly Mentioned Not noted “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION” “Airy-soft texture — Shiseido Essential Energy Hydrating Cream” “absorbs quickly — Shiseido White Lucent Brightening Gel Cream”
- Radiance and brightening Often Mentioned Often Mentioned “Skin looks brighter, more radiant, and "glowy." — Shiseido Ultimune Power Infusing Concentrate” “faded pimple marks — Shiseido White Lucent Brightening Gel Cream” “Eyes look more awake — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “lit-from-within look — MAC Hyper Real Serumizer”
- Lightweight hydration Not noted Mostly Mentioned “absorbs quickly — MAC Hyper Real Serumizer” “Absorbs in a snap — MAC Mineralize Timecheck Lotion”
- Smoother skin Often Mentioned Sometimes Noted “Velvety smooth — Shiseido FUTURE SOLUTION LX” “makes skin baby soft — Shiseido Benefiance Wrinkle Smoothing Cream Enriched” “smoothes rough skin — Shiseido Eudermine Revitalizing Essence” “petal-soft skin — MAC Hyper Real Serumizer”
- High price Mostly Mentioned Mostly Mentioned “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Expensive, pricey, high cost for the amount. — Shiseido Ultimune Power Infusing Concentrate” “too expensive — MAC Hyper Real Serumizer” “A bit expensive — MAC Mineralize Timecheck Lotion”
- Strong fragrance and scent Often Mentioned Often Mentioned “scent is overpowering — MAC Hyper Real Serumizer” “Has a scent that might irritate very sensitive noses. — MAC Hyper Real Fresh Canvas Cleansing Oil” “old lady smell — Shiseido Eudermine Revitalizing Essence”
- Skin irritation and reactions Sometimes Noted Sometimes Noted “Caused some irritation — Shiseido Bio-Performance Advanced Super Revitalizing Cream” “Caused burning and redness — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “caused acne — MAC Hyper Real Serumizer” “Stings if it accidentally gets into the eyes. — MAC Hyper Real Fresh Canvas Cleansing Oil”

## Questions and answers

### Shiseido or MAC: which is better?

Shiseido is often better for deep hydration and radiance, while MAC is known for makeup base compatibility and lightweight hydration. Topical [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid) helps improve skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Shiseido and MAC?

Shiseido is best for deep hydration, luxurious textures, and radiance, while MAC is known for its makeup bases, primers, and lightweight hydration. Hyaluronic acid helps both brands deliver moisture to the skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Shiseido or MAC: which moisturizer is better?

Shiseido is a better choice for moisturizers if you want deep hydration and anti-aging benefits, while MAC is better known for lightweight moisturizers. Topical hyaluronic acid helps improve skin quality and signs of skin aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Shiseido or MAC?

Shiseido and MAC are equally high in price, as reviewers mostly note a high price point for the products on this page for both brands.

### Which causes fewer breakouts, Shiseido or MAC?

Reviewers and page facts do not specify breakout comparisons or acne rates between Shiseido and MAC, so neither brand can be declared to cause fewer breakouts.

### How do the origins and ownership of Shiseido and MAC compare?

Shiseido was founded in 1872 in Japan and is owned by Shiseido Company, Limited, whereas MAC was founded in 1984 in Canada and is owned by The Estée Lauder Companies Inc.

### Which brand has more products that are free of fragrance?

Shiseido has more products on this page that are free of fragrance, with 5 fragrance-free options compared to MAC which has none.

### What specific review themes favor Shiseido over MAC in skincare performance?

Shiseido is favored over MAC in skincare performance for deep hydration, luxurious texture, radiance and brightening, and smoother skin. Topical hyaluronic acid helps improve skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/25607790/) Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014
- [Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/26655409/) Sanguisorba officinalis root extract · Phytomedicine, 2015
- [Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/18007579/) Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica seed oil · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies](https://pubmed.ncbi.nlm.nih.gov/30442066/) Lauric acid · Drug Development and Industrial Pharmacy, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol](https://pubmed.ncbi.nlm.nih.gov/26517086/) Paeonia albiflora flower extract · Medical Science Monitor, 2015
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Paeonia albiflora flower extract · Molecules, 2023
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy](https://pubmed.ncbi.nlm.nih.gov/33804924/) Sodium lauryl sulfate · Pharmaceutics, 2021
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate](https://pubmed.ncbi.nlm.nih.gov/20358390/) Sodium lauryl sulfate · Inflammation Research, 2010
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them](https://pubmed.ncbi.nlm.nih.gov/28631090/) Ceramide ng · Archives of Dermatological Research, 2017
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin](https://pubmed.ncbi.nlm.nih.gov/16676123/) Paeonia albiflora flower extract · Journal of Cosmetic Science, 2006
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 2-o-ethyl ascorbic acid · Polymers, 2023
- [Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/37805147/) Lauric acid · International Journal of Pharmaceutics, 2023
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/30637727/) Sodium lauryl sulfate · The British Journal of Dermatology, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Theanine · Journal of Clinical Medicine, 2022
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin](https://pubmed.ncbi.nlm.nih.gov/39946269/) Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) 2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/40071590/) Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025
- [New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging](https://pubmed.ncbi.nlm.nih.gov/39598529/) Angelica keiskei leaf extract · Pharmaceutics, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Uji green tea extract · Journal of Cosmetic Dermatology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025

## The brands

- Japanese skincare: [Shiseido](https://lovi.care/skincare/es/brands/shiseido)
- Canadian skincare: [MAC](https://lovi.care/skincare/es/brands/mac)

## More comparisons

- [SKIN1004 vs Shiseido](https://lovi.care/skincare/es/compare/skin1004-vs-shiseido)
- [SKIN1004 vs MAC](https://lovi.care/skincare/es/compare/skin1004-vs-mac)
- [Anua vs Shiseido](https://lovi.care/skincare/es/compare/anua-vs-shiseido)
- [Anua vs MAC](https://lovi.care/skincare/es/compare/anua-vs-mac)
- [Medicube vs Shiseido](https://lovi.care/skincare/es/compare/medicube-vs-shiseido)
- [Medicube vs MAC](https://lovi.care/skincare/es/compare/medicube-vs-mac)
- [The Ordinary vs Shiseido](https://lovi.care/skincare/es/compare/the-ordinary-vs-shiseido)
- [The Ordinary vs MAC](https://lovi.care/skincare/es/compare/the-ordinary-vs-mac)
- [Beauty of Joseon vs Shiseido](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-shiseido)
- [Beauty of Joseon vs MAC](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-mac)
- [COSRX vs Shiseido](https://lovi.care/skincare/es/compare/cosrx-vs-shiseido)
- [COSRX vs MAC](https://lovi.care/skincare/es/compare/cosrx-vs-mac)
- [CeraVe vs Shiseido](https://lovi.care/skincare/es/compare/cerave-vs-shiseido)
- [CeraVe vs MAC](https://lovi.care/skincare/es/compare/cerave-vs-mac)
- [La Roche-Posay vs Shiseido](https://lovi.care/skincare/es/compare/la-roche-posay-vs-shiseido)
- [La Roche-Posay vs MAC](https://lovi.care/skincare/es/compare/la-roche-posay-vs-mac)
- [Dr. Althea vs Shiseido](https://lovi.care/skincare/es/compare/dr-althea-vs-shiseido)
- [Dr. Althea vs MAC](https://lovi.care/skincare/es/compare/dr-althea-vs-mac)
- [Some By Mi vs Shiseido](https://lovi.care/skincare/es/compare/some-by-mi-vs-shiseido)
- [Some By Mi vs MAC](https://lovi.care/skincare/es/compare/some-by-mi-vs-mac)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/shiseido-vs-mac
- United Kingdom: https://lovi.care/skincare/uk/compare/shiseido-vs-mac
- Ireland: https://lovi.care/skincare/ie/compare/shiseido-vs-mac
- Germany: https://lovi.care/skincare/de/compare/shiseido-vs-mac
- France: https://lovi.care/skincare/fr/compare/shiseido-vs-mac
- Italy: https://lovi.care/skincare/it/compare/shiseido-vs-mac
- Netherlands: https://lovi.care/skincare/nl/compare/shiseido-vs-mac
- Spain: https://lovi.care/skincare/es/compare/shiseido-vs-mac (this page)
- Canada: https://lovi.care/skincare/ca/compare/shiseido-vs-mac
- Australia: https://lovi.care/skincare/au/compare/shiseido-vs-mac
- Singapore: https://lovi.care/skincare/sg/compare/shiseido-vs-mac
- Saudi Arabia: https://lovi.care/skincare/sa/compare/shiseido-vs-mac
- United Arab Emirates: https://lovi.care/skincare/ae/compare/shiseido-vs-mac