# Sesderma vs Omorovicza

Page: https://lovi.care/skincare/es/compare/sesderma-vs-omorovicza

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Sesderma and Omorovicza are two distinct skincare houses offering targeted solutions for diverse complexions. The Spanish enterprise founded in 1989 is known for advanced [serums](https://lovi.care/skincare/es/ingredients/serum) with active compounds that suit sensitive, hyperpigmented, and aging skin. Meanwhile, the Hungarian brand is beloved for mineral-rich clarifying toners and purifying masks tailored to dry, oily, and combination skin. While both deliver effective daily care, they differ in their foundational ingredients and primary textures.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular Sesderma and Omorovicza products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgd1f1d27ef7).

### Popular Sesderma vs Omorovicza products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/es/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€35.16 at Amazon](https://www.amazon.de/dp/B00987RKWW?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Omorovicza

- [Queen of Hungary Mist](https://lovi.care/skincare/es/p/omorovicza/queen-of-hungary-mist/for/sensitive-skin) — High fit — [€82.00 at Notino](https://www.notino.es/omorovicza/queen-of-hungary-mist-bruma-refrescante-para-el-rostro/p-16392605/)
- [Deep Cleansing Mask](https://lovi.care/skincare/es/p/omorovicza/deep-cleansing-mask/for/acne-prone-skin) — High fit

## Questions and answers

### Sesderma or Omorovicza: which is better?

Omorovicza is better for acne-prone, oily, and dry skin types on this page, where its products achieve High Lovi fit levels. Sesderma achieves a High Lovi fit level for acne-prone skin and skin with dark spots.

### What is the difference between Sesderma and Omorovicza?

Sesderma offers the Azelac RU [Serum](https://lovi.care/skincare/es/ingredients/serum), while Omorovicza features the Queen of Hungary Mist and the Deep Cleansing Mask on this page. Lovi rates Sesderma as having a High fit for acne-prone skin and skin with dark spots, whereas Omorovicza achieves a High fit for sensitive and dry skin with its toner and for oily and acne-prone skin with its mask.

### Which is more affordable, Sesderma or Omorovicza?

This page does not compare the prices of Sesderma and Omorovicza, so it cannot be determined which brand is more affordable.

### Which causes fewer breakouts, Sesderma or Omorovicza?

Omorovicza is more likely to help with breakouts because the Deep Cleansing Mask on this page has a High Lovi fit for acne-prone skin, while the Sesderma serum has an Average fit.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which brand was founded earlier, Sesderma or Omorovicza?

Sesderma was founded earlier in 1989 in Spain, while Omorovicza was founded in 2006.

### Do Sesderma and Omorovicza products contain fragrance?

Yes, both brands include fragrance in their products on this page. Omorovicza has fragrance in the Deep Cleansing Mask while the Queen of Hungary Mist lists no fragrance, and Sesderma includes fragrance in the Azelac RU Serum.

### Which brand offers a serum for skin with dark spots?

Sesderma offers the Azelac RU Serum for skin with dark spots, for which Lovi shows a High fit level.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Effect of São Pedro do Sul thermal water on skin irritation](https://pubmed.ncbi.nlm.nih.gov/20557578/) Water hungarian thermal water · International Journal of Cosmetic Science, 2010
- [Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/27168163/) Phenoxyethanol · International Journal of Cosmetic Science, 2017
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin](https://pubmed.ncbi.nlm.nih.gov/32242497/) Pyrus malus fruit extract · Rejuvenation Research, 2020
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/35048513/) Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Water hungarian thermal water · Journal of the European Academy of Dermatology and Venereology, 2020
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Water hungarian thermal water · The Medical Journal of Malaysia, 2024
- [Biophysical effects of a natural peloid on normal skin](https://pubmed.ncbi.nlm.nih.gov/37957435/) Sea silt hungarian mud · International Journal of Biometeorology, 2024

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/es/brands/sesderma)
- Skincare: [Omorovicza](https://lovi.care/skincare/es/brands/omorovicza)

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- [La Roche-Posay vs Sesderma](https://lovi.care/skincare/es/compare/la-roche-posay-vs-sesderma)
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- [Some By Mi vs Sesderma](https://lovi.care/skincare/es/compare/some-by-mi-vs-sesderma)
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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/sesderma-vs-omorovicza
- United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-omorovicza
- Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-omorovicza
- Germany: https://lovi.care/skincare/de/compare/sesderma-vs-omorovicza
- France: https://lovi.care/skincare/fr/compare/sesderma-vs-omorovicza
- Italy: https://lovi.care/skincare/it/compare/sesderma-vs-omorovicza
- Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-omorovicza
- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-omorovicza (this page)
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-omorovicza
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-omorovicza
- Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-omorovicza
- Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-omorovicza
- United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-omorovicza