# Sesderma vs ILIA Beauty

Page: https://lovi.care/skincare/es/compare/sesderma-vs-ilia-beauty

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Sesderma and ILIA Beauty are distinct skincare houses offering tailored approaches to daily wellness. The former is a Spanish brand beloved for its advanced [serums](https://lovi.care/skincare/es/ingredients/serum) and meticulously engineered formulas featuring botanical [extracts](https://lovi.care/skincare/es/ingredients/extract) and active compounds that refine skin texture, suiting sensitive, hyperpigmented, and aging skin best, with the Azelac RU Serum standing out for acne-prone skin. Meanwhile, the Canadian brand is widely loved for its thoughtful moisturizers and nourishing, clean compositions that suit dry, normal, and combination skin, with The Base Face Milk acting as a standout for acne-prone skin. Ultimately, both differ through their unique ingredient philosophies, with the former focusing on active compounds and the latter emphasizing gentle hydration.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

ILIA Beauty is a Canadian skincare brand founded in 2011 and owned by Famille C since 2022.

[tracxn.com](https://tracxn.com/d/companies/ilia-beauty/__9WyJY6jBVsIpf6X5oVASXK-LuJlDTWhr53W5UcX5jlw) [cosmeticsbusiness.com](https://cosmeticsbusiness.com/ilia-beauty-lands-paul-schiraldi-as-ceo)

This page compares some of the most popular Sesderma and ILIA Beauty products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgea6f1f9765).

### Popular Sesderma vs ILIA Beauty products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/es/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€35.16 at Amazon](https://www.amazon.de/dp/B00987RKWW?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### ILIA Beauty

- [The Base Face Milk](https://lovi.care/skincare/es/p/ilia-beauty/the-base-face-milk/for/dark-spots) — Average fit

## Questions and answers

### Sesderma or ILIA Beauty: which is better?

Sesderma earns a High Lovi fit for acne-prone skin and dark spots with its Azelac RU [Serum](https://lovi.care/skincare/es/ingredients/serum), whereas ILIA Beauty offers average fits across all skin types for the products on this page. Sesderma includes fragrance in its serum, while ILIA Beauty lists no fragrance in The Base Face Milk.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### What is the difference between Sesderma and ILIA Beauty?

Sesderma offers Azelac RU Serum, which has a High Lovi fit for acne-prone skin and skin with dark spots, whereas ILIA Beauty features The Base Face Milk, which has an Average fit across all listed skin types. The products on this page from Sesderma contain fragrance, while every product on this page from ILIA Beauty lists no fragrance in its ingredients.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which is more affordable, Sesderma or ILIA Beauty?

Neither Sesderma nor ILIA Beauty can be called more affordable because the products on this page do not list any prices.

### Which causes fewer breakouts, Sesderma or ILIA Beauty?

ILIA Beauty helps cause fewer breakouts because its moisturizer on this page has an average fit for acne-prone skin, whereas Sesderma has a high fit for acne-prone skin with its Azelac RU Serum. [Azelaic acid](https://lovi.care/skincare/es/ingredients/azelaic-acid) helps reduce acne vulgaris.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Which brand is older, Sesderma or ILIA Beauty?

Sesderma is older than ILIA Beauty, having been founded in Spain in 1989 compared to ILIA Beauty which was founded in Canada in 2011.

### Which company owns Sesderma and which owns ILIA Beauty?

Grupo Sesderma owns Sesderma, and Famille C owns ILIA Beauty.

### Do Sesderma products contain fragrance compared to ILIA Beauty products?

Sesderma includes fragrance in its Azelac RU Serum on this page, whereas every ILIA Beauty product on this page lists no fragrance.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration](https://pubmed.ncbi.nlm.nih.gov/25143733/) Argania spinosa kernel oil · International Journal of Nanomedicine, 2014
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Argania spinosa kernel oil · Lasers in Medical Science, 2025

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/es/brands/sesderma)
- Canadian skincare: [ILIA Beauty](https://lovi.care/skincare/es/brands/ilia-beauty)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- Spain: https://lovi.care/skincare/es/compare/sesderma-vs-ilia-beauty (this page)
- Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-ilia-beauty
- Australia: https://lovi.care/skincare/au/compare/sesderma-vs-ilia-beauty
- Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-ilia-beauty
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