# Sesderma vs Aēsop

Page: https://lovi.care/skincare/es/compare/sesderma-vs-aesop

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Sesderma and Aēsop are two distinct skincare lines known for distinct botanical and active ingredients. The Spanish brand founded in 1989 is beloved for advanced [serums](https://lovi.care/skincare/es/ingredients/serum) and meticulously engineered formulas, while the other is widely loved for thoughtfully formulated moisturizers, cleansers, and serums. Sesderma suits sensitive, hyperpigmented, and aging skin types best, whereas Aēsop suits balanced, combination, and sensitive skin best. They differ in their targeted solutions, such as the Azelac RU Serum for acne-prone skin from the former, and the B Triple C Facial Balancing Gel, Parsley Seed Anti-Oxidant Intense Serum, and [Damascan Rose](https://lovi.care/skincare/es/ingredients/rose) Facial Treatment from the latter.

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular Sesderma and Aēsop products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg2f68584835).

### Popular Sesderma vs Aēsop products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/es/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€35.16 at Amazon](https://www.amazon.de/dp/B00987RKWW?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Aēsop

- [Parsley Seed Facial Cleanser](https://lovi.care/skincare/es/p/aesop/parsley-seed-facial-cleanser/for/acne-prone-skin) — Average fit
- [Damascan Rose Facial Treatment](https://lovi.care/skincare/es/p/aesop/damascan-rose-facial-treatment/for/dry-skin) — High fit
- [B Triple C Facial Balancing Gel](https://lovi.care/skincare/es/p/aesop/b-triple-c-facial-balancing-gel/for/combination-skin) — High fit
- [Parsley Seed Anti-Oxidant Intense Serum](https://lovi.care/skincare/es/p/aesop/parsley-seed-anti-oxidant-intense-serum/for/dark-spots) — High fit

## Questions and answers

### Sesderma or Aēsop: which is better?

Both brands offer good options, but Aēsop stands out with the Parsley Seed Anti-Oxidant Intense [Serum](https://lovi.care/skincare/es/ingredients/serum), which Lovi rates as having a High fit across all skin types.

### What is the difference between Sesderma and Aēsop?

Sesderma and Aēsop differ in their product offerings and formulation details on this page, as Sesderma features a scented serum with high fits for acne-prone and dark spots, whereas Aēsop provides a range of unscented moisturizers, cleansers, and serums where the Parsley Seed Anti-Oxidant Intense Serum achieves a High fit across all listed skin types.

### Which is more affordable, Sesderma or Aēsop?

Aēsop has a high price mentioned by reviewers, while the page has no pricing information for Sesderma.

### Which causes fewer breakouts, Sesderma or Aēsop?

Aēsop offers products on this page like B Triple C Facial Balancing Gel that get a High fit for acne-prone skin, while Sesderma's Azelac RU Serum gets an Average fit.

### Which brand uses fragrance in its products, Sesderma or Aēsop?

Sesderma uses fragrance in the products on this page, while every Aēsop product on this page lists no fragrance in its ingredients.

### How do the founding years and current ownership of Sesderma and Aēsop compare?

Sesderma was founded in Spain in 1989 and is owned by Grupo Sesderma, while Aēsop was founded in 1987 and is owned by L'Oréal Groupe.

### What do reviewers say about the scent and pricing of Aēsop products?

Reviewers frequently mention that Aēsop products feature luxurious and refreshing scents, though some note unpleasant scents on occasion. Additionally, a high price is a mostly mentioned drawback by shoppers.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Lactate triggers KAT8-mediated LTBP1 lactylation at lysine 752 to promote skin rejuvenation by inducing collagen synthesis in fibroblasts](https://pubmed.ncbi.nlm.nih.gov/39102921/) Lactic acid · International Journal of Biological Macromolecules, 2024
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica seed oil · Journal of Ethnopharmacology, 2007
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway](https://pubmed.ncbi.nlm.nih.gov/36575891/) Lactic acid · Journal of Cosmetic Dermatology, 2023
- [Application of Standardized Rosa damascena Stem Cell-Derived Exosomes in Dermatological Wound Healing and Scar Management: A Retrospective Case-Series Study with Long-Term Outcome Assessment](https://pubmed.ncbi.nlm.nih.gov/40733118/) Damascan rose · Pharmaceutics, 2025
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel water · Phytochemistry, 2001
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil · Biomaterials Advances, 2022
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin](https://pubmed.ncbi.nlm.nih.gov/22236139/) Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil](https://pubmed.ncbi.nlm.nih.gov/24451077/) Rosa damascena oil flower, Damascan rose · Acta Pharmaceutica, 2013
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Highly efficient and compatible shampoo for use after hair transplant](https://pubmed.ncbi.nlm.nih.gov/26229498/) Chamomilla recutita oil flower matricaria oil flower · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Evolution of lipid composition in skin treated with blackcurrant seed oil](https://pubmed.ncbi.nlm.nih.gov/19456920/) Ribes nigrum seed oil · International Journal of Cosmetic Science, 1988
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026

## The brands

- Spanish skincare: [Sesderma](https://lovi.care/skincare/es/brands/sesderma)
- Skincare: [Aēsop](https://lovi.care/skincare/es/brands/aesop)

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- [Some By Mi vs Aēsop](https://lovi.care/skincare/es/compare/some-by-mi-vs-aesop)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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