REN Clean Skincare vs Trilogy

Questions and answers

Research behind their key ingredients

• Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

  Sodium hyaluronate · Dermatologic Therapy, 2022

• Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial

  Ascorbic acid · Journal of Cosmetic Dermatology, 2020

• Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations

  Aloe barbadensis leaf juice · Clinical Pharmacology, 2018

• Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin

  Ceramide np · International Journal of Dermatology, 2008

• Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation

  Ascorbic acid · Journal of Cosmetic Dermatology, 2020

• The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study

  Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017

• Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris

  Triethyl citrate · The British Journal of Dermatology, 2007

• Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study

  Jojoba seed oil · Forschende Komplementarmedizin, 2012

• A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid

  Ceramide np · Skin Pharmacology and Physiology, 2022

• Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model

  Jojoba seed oil · Frontiers in Pharmacology, 2024

• Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison

  Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2019

• Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract

  Salix nigra bark extract willow bark extract · Planta Medica, 2019

• An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging

  Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2010

• Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study

  Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020

• A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo

  Shea butter · Journal of Cosmetic Dermatology, 2022

• Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial

  Shea butter · Lasers in Medical Science, 2025

• Monocentric, Vehicle-Controlled, Double-Blind Study to Assess the Short- and Long-Term Effects of a Ceramide NP C15-Containing Emollient on the Skin Microbiome and the Skin Barrier Function in Sensitive Skin

  Ceramide iii · Skin Pharmacology and Physiology, 2026

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.