# Pixi vs Natura Bissé

Page: https://lovi.care/skincare/es/compare/pixi-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Pixi and Natura Bissé are British and Spanish skincare brands founded in 1999 and 1979, respectively. Pixi is beloved for its thoughtful range of toners, [serums](https://lovi.care/skincare/es/ingredients/serum), eye products, and moisturizers crafted with gentle yet effective formulas, while Natura Bissé is loved for its luxurious moisturizers and advanced formulas. The former suits sensitive skin and acne-prone skin best owing to their soothing and balancing nature, whereas the latter suits mature, dry, and sensitive skin best due to their rich nourishing properties. Both brands differ in their specific standout offerings and primary target concerns, ranging from the Glow Tonic, Glow Peel Pads, and [Retinol](https://lovi.care/skincare/es/ingredients/retinol) Tonic for the British line to the Diamond Extreme for the Spanish line.

Pixi is a British skincare brand founded in 1999.

[pixibeauty.com](https://www.pixibeauty.com/pages/about-us) [tracxn.com](https://tracxn.com/d/companies/pixi/__9im1wKbH2BlPhvu7p7lH3hjmApgKsoxMqsd9FqFjrCE) [pitchbook.com](https://pitchbook.com/profiles/company/454901-05)

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Pixi and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pga5b0afa561).

### Popular Pixi vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/es/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [€266.00 at Amazon](https://www.amazon.de/dp/B0BKLRMKZV?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Pixi

- [Glow Tonic](https://lovi.care/skincare/es/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€11.50 at Notino](https://www.notino.es/pixi/glow-tonico-facial-calmante-con-acido-glicolico/p-16299386/)
- [DetoxifEYE Depuffing Eye Patches](https://lovi.care/skincare/es/p/pixi/detoxifeye-depuffing-eye-patches/for/oily-skin) — High fit
- [Hydrating Milky Mist](https://lovi.care/skincare/es/p/pixi/hydrating-milky-mist/for/sensitive-skin) — Superior fit
- [Glow Mist](https://lovi.care/skincare/es/p/pixi/glow-mist/for/dry-sensitive-skin) — High fit
- [Glow Peel Pads](https://lovi.care/skincare/es/p/pixi/glow-peel-pads/for/dark-spots) — Superior fit
- [Rose Oil Blend](https://lovi.care/skincare/es/p/pixi/rose-oil-blend/for/dry-skin) — High fit
- [Vitamin-C Serum](https://lovi.care/skincare/es/p/pixi/vitamin-c-serum/for/dark-spots) — High fit — [€25.90 at Notino](https://www.notino.es/pixi/vitamin-c-serum-facial-iluminador-con-vitamina-c/p-16372656/)
- [Retinol Tonic](https://lovi.care/skincare/es/p/pixi/retinol-tonic/for/mature-skin) — Superior fit

## Questions and answers

### Pixi or Natura Bissé: which is better?

Pixi offers a much wider variety of products on this page with high to superior Lovi fit levels for sensitive and acne-prone skin, whereas Natura Bissé features only a single luxury moisturizer. Reviewers note that Pixi delivers deep hydration and radiance, although some mention a sticky residue.

### What is the difference between Pixi and Natura Bissé?

Pixi offers a wide range of ten products featuring key ingredients like [aloe vera](https://lovi.care/skincare/es/ingredients/aloe-vera) and [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid), whereas Natura Bissé is represented by a single luxury moisturizer called Diamond Extreme. Pixi fits best for sensitive, acne-prone, and dry sensitive skin, with its products on this page achieving Superior ratings across multiple skin types.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/)

### Pixi or Natura Bissé: which moisturizer is better?

Pixi [Rose Oil](https://lovi.care/skincare/es/ingredients/rose) Blend and Natura Bissé Diamond Extreme are the moisturizers on this page. Lovi rates Pixi Rose Oil Blend as a High fit for dry skin and a Low fit for oily and combination skin, while Natura Bissé Diamond Extreme is a Superior fit for mature skin and a High fit for dry and dry sensitive skin.

### Which is more affordable, Pixi or Natura Bissé?

The provided page facts and studies do not contain pricing information, so it is not possible to determine whether Pixi or Natura Bissé is more affordable.

### Which causes fewer breakouts, Pixi or Natura Bissé?

Pixi fits acne-prone skin with a Superior level for products like [Retinol](https://lovi.care/skincare/es/ingredients/retinol) Tonic and Glow Tonic, whereas Natura Bissé has an Average fit for acne-prone skin with Diamond Extreme. Pixi's aloe vera helps soothe skin and may prevent irritation while you treat blemishes.

[Iranian Journal of Medical Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/30666070/)

### Between Pixi and Natura Bissé, which brand was founded earlier and in which country?

Natura Bissé was founded earlier than Pixi, having been established in Spain in 1979 compared to Pixi's founding in the United Kingdom in 1999.

### How do the fragrance inclusions compare between Pixi and Natura Bissé products on the page?

Pixi features ten products on the page with seven listing no fragrance, while Natura Bissé has one product that includes fragrance.

### Which Pixi products offer a Superior Lovi fit level for mature skin?

For mature skin, Glow Tonic and Retinol Tonic offer a Superior Lovi fit level among the products on this page. Retinol helps stimulate [collagen](https://lovi.care/skincare/es/ingredients/collagen) accumulation in naturally aged human skin.

[The Journal of Investigative Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10692106/)

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Sambucus nigra L. ameliorates UVB-induced photoaging and inflammatory response in human skin keratinocytes](https://pubmed.ncbi.nlm.nih.gov/31512082/) Sambucus nigra extract · Cytotechnology, 2019
- [Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration](https://pubmed.ncbi.nlm.nih.gov/25143733/) Argania spinosa kernel oil · International Journal of Nanomedicine, 2014
- [Improvement of skin condition in striae distensae: development, characterization and clinical efficacy of a cosmetic product containing Punica granatum seed oil and Croton lechleri resin extract](https://pubmed.ncbi.nlm.nih.gov/28280300/) Punica granatum seed oil · Drug Design, Development and Therapy, 2017
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract, Witch hazel extract · Phytochemistry, 2001
- [Anti-melanogenic property of ginsenoside Rf from Panax ginseng via inhibition of CREB/MITF pathway in melanocytes and ex vivo human skin](https://pubmed.ncbi.nlm.nih.gov/34803425/) Panax ginseng root extract · Journal of Ginseng Research, 2021
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin](https://pubmed.ncbi.nlm.nih.gov/22236139/) Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012
- [A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors](https://pubmed.ncbi.nlm.nih.gov/33081083/) Rose extract · Molecules, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Biochemical Pilot Study on Effects of Pomegranate Seed Oil Extract and Cosmetic Cream on Neurologically Mediated Skin Inflammation in Animals and Humans: A Comparative Observational Study](https://pubmed.ncbi.nlm.nih.gov/36677961/) Punica granatum seed oil · Molecules, 2023
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits](https://pubmed.ncbi.nlm.nih.gov/36293365/) Betula alba juice · International Journal of Molecular Sciences, 2022
- [Antiaging, Brightening, and Antioxidant Efficacy of Fermented Bilberry Extract (Vaccinium myrtillus): A Randomized, Double-Blind, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/39064646/) Vaccinium myrtillus fruit extract · Nutrients, 2024
- [Permeation, metabolism and site of action concentration of nicotinic acid derivatives in human skin. Correlation with topical pharmacological effect](https://pubmed.ncbi.nlm.nih.gov/14550884/) Hexyl nicotinate · European Journal of Pharmaceutical Sciences, 2003
- [Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil](https://pubmed.ncbi.nlm.nih.gov/24451077/) Rosa damascena oil flower · Acta Pharmaceutica, 2013
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study](https://pubmed.ncbi.nlm.nih.gov/32379165/) Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Hexyl-nicotinate-induced vasodilation in normal human skin](https://pubmed.ncbi.nlm.nih.gov/3582710/) Hexyl nicotinate · Dermatologica, 1987
- [Development and Evaluation of Cucurbitacin B Microemulsion: the Effect of Oil Phase and Aqueous Phase on Drug Percutaneous Absorption Based on ATR-FTIR Spectroscopy and Molecular Modeling](https://pubmed.ncbi.nlm.nih.gov/32895882/) Cucumis sativus extract · AAPS PharmSciTech, 2020
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [The effects of topically applied hexyl nicotinate lotion on the cutaneous blood flow in patients with Raynaud's phenomenon](https://pubmed.ncbi.nlm.nih.gov/3203071/) Hexyl nicotinate · The British Journal of Dermatology, 1988
- [Clinical study of a spray containing birch juice for repairing sensitive skin](https://pubmed.ncbi.nlm.nih.gov/36961534/) Betula alba juice · Archives of Dermatological Research, 2023
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- British skincare: [Pixi](https://lovi.care/skincare/es/brands/pixi)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/es/brands/natura-bisse)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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