# ISDIN vs A+

Page: https://lovi.care/skincare/es/compare/isdin-vs-a

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

ISDIN and A+ are established skincare houses that offer gentle daily care and reliable moisture balance. The Spanish brand is known for advanced sunscreens, targeted [serums](https://lovi.care/skincare/es/ingredients/serum), and soothing eye products driven by expert formulas, while the Indian house is widely beloved for thoughtfully calibrated formulations. Both options suit sensitive skin best, though the Puig-owned line also provides rich nourishment for mature complexions and specialized support for dark spots or acne-prone areas. Ultimately, they differ in their heritage and breadth of specialized treatments, with the older European entity featuring a wider array of targeted solutions.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

A+ is an Indian skincare brand founded in 1990.

[pitchbook.com](https://pitchbook.com/profiles/company/554388-85)

This page compares some of the most popular ISDIN and A+ products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgdfb1b13559).

### Popular ISDIN vs A+ products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/es/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [€32.49 at Amazon](https://www.amazon.de/dp/B0875W6QQG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/es/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [€25.99 at Amazon](https://www.amazon.de/dp/B00Z72U6JQ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/es/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [€49.00 at Amazon](https://www.amazon.de/dp/B01BMLQ4JQ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/es/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/es/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/es/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [€44.30 at Amazon](https://www.amazon.de/dp/B01BMLQ086?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/es/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/es/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [€59.55 at Amazon](https://www.amazon.de/dp/B0BD9DK6SC?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### A+

- [345 Relief Cream](https://lovi.care/skincare/es/p/a/345-relief-cream/for/sensitive-skin) — Average fit

## Questions and answers

### ISDIN or A+: which is better?

ISDIN offers a wider variety of products on this page with better Lovi fit levels across skin types, whereas A+ has only a single fragrance-free moisturizer listed. ISDIN sunscreens may help protect skin and are well-liked by reviewers, though some products contain fragrance and carry a higher price point.

### What is the difference between ISDIN and A+?

ISDIN offers a larger variety of products on this page across categories like sunscreens, moisturizers, and [serums](https://lovi.care/skincare/es/ingredients/serum), with Lovi fit levels reaching Superior for specific skin types, whereas A+ features only one moisturizer with Average fits. Additionally, ISDIN includes fragrance in several of its formulas, while A+ lists no fragrance in any product on this page.

### ISDIN or A+: which moisturizer is better?

For moisturizers, the products on this page show that ISDIN Hyaluronic Concentrate has a High fit level for sensitive and acne-prone skin, while A+ 345 Relief Cream has an Average fit for those skin types. Topical [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid) helps improve skin hydration and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, ISDIN or A+?

Reviewers note that ISDIN has a high price point, whereas A+ is not mentioned as having high prices.

### Which causes fewer breakouts, ISDIN or A+?

When it comes to breakout-prone skin, the products on this page from both ISDIN and A+ include options that are generally well-tolerated, though ISDIN offers a wider variety of formulas with high fit levels for acne-prone skin.

### How do the founding years and ownership of ISDIN and A+ compare?

ISDIN was founded in 1975 in Spain and is owned by Puig, whereas A+ was founded in 1990 in India and is independently owned.

### Which brand has more fragrance-free products, ISDIN or A+?

A+ has more fragrance-free products on this page, as every product from A+ lists no fragrance, whereas 3 of 8 ISDIN products list no fragrance.

### What are the most common reviewer complaints about ISDIN?

Reviewers often complain about the high price point of ISDIN products. They also sometimes note a strong fragrance.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/es/brands/isdin)
- Indian skincare: [A+](https://lovi.care/skincare/es/brands/a)

## More comparisons

- [SKIN1004 vs ISDIN](https://lovi.care/skincare/es/compare/skin1004-vs-isdin)
- [SKIN1004 vs A+](https://lovi.care/skincare/es/compare/skin1004-vs-a)
- [Anua vs ISDIN](https://lovi.care/skincare/es/compare/anua-vs-isdin)
- [Anua vs A+](https://lovi.care/skincare/es/compare/anua-vs-a)
- [Medicube vs ISDIN](https://lovi.care/skincare/es/compare/medicube-vs-isdin)
- [Medicube vs A+](https://lovi.care/skincare/es/compare/medicube-vs-a)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/es/compare/the-ordinary-vs-isdin)
- [The Ordinary vs A+](https://lovi.care/skincare/es/compare/the-ordinary-vs-a)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-isdin)
- [Beauty of Joseon vs A+](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-a)
- [COSRX vs ISDIN](https://lovi.care/skincare/es/compare/cosrx-vs-isdin)
- [COSRX vs A+](https://lovi.care/skincare/es/compare/cosrx-vs-a)
- [CeraVe vs ISDIN](https://lovi.care/skincare/es/compare/cerave-vs-isdin)
- [CeraVe vs A+](https://lovi.care/skincare/es/compare/cerave-vs-a)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/es/compare/la-roche-posay-vs-isdin)
- [La Roche-Posay vs A+](https://lovi.care/skincare/es/compare/la-roche-posay-vs-a)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/es/compare/dr-althea-vs-isdin)
- [Dr. Althea vs A+](https://lovi.care/skincare/es/compare/dr-althea-vs-a)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/es/compare/some-by-mi-vs-isdin)
- [Some By Mi vs A+](https://lovi.care/skincare/es/compare/some-by-mi-vs-a)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/isdin-vs-a
- United Kingdom: https://lovi.care/skincare/uk/compare/isdin-vs-a
- Ireland: https://lovi.care/skincare/ie/compare/isdin-vs-a
- Germany: https://lovi.care/skincare/de/compare/isdin-vs-a
- France: https://lovi.care/skincare/fr/compare/isdin-vs-a
- Italy: https://lovi.care/skincare/it/compare/isdin-vs-a
- Netherlands: https://lovi.care/skincare/nl/compare/isdin-vs-a
- Spain: https://lovi.care/skincare/es/compare/isdin-vs-a (this page)
- Canada: https://lovi.care/skincare/ca/compare/isdin-vs-a
- Australia: https://lovi.care/skincare/au/compare/isdin-vs-a
- Singapore: https://lovi.care/skincare/sg/compare/isdin-vs-a
- Saudi Arabia: https://lovi.care/skincare/sa/compare/isdin-vs-a
- United Arab Emirates: https://lovi.care/skincare/ae/compare/isdin-vs-a