# Good Molecules vs Simple

Page: https://lovi.care/skincare/es/compare/good-molecules-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Good Molecules and Simple are skin care brands that offer targeted daily formulations for diverse complexions. The American brand is cherished for its [serums](https://lovi.care/skincare/es/ingredients/serum), moisturizers, eye products, and exfoliants featuring [glycerin](https://lovi.care/skincare/es/ingredients/glycerin) and [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid), suiting dry and combination skin best. Meanwhile, the British brand is deeply loved for its gentle moisturizers, makeup removers, cleansers, and toners incorporating [niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide) and glycerin, which suit oily and acne-prone skin best. These two options differ primarily in their ingredient profiles, specific product lineups, and the primary skin types they are designed to support.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

[beautymatter.com](https://beautymatter.com/articles/aria-growth-partners-makes-investment-in-good-molecules) [goodmolecules.com](https://www.goodmolecules.com/about) [pitchbook.com](https://pitchbook.com/profiles/company/458272-45) [preqin.com](https://www.preqin.com/data/profile/asset/good-molecules--llc-/802471)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular Good Molecules and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg306fa2209c).

### Popular Good Molecules vs Simple products

#### Good Molecules

- [Discoloration Correcting Serum](https://lovi.care/skincare/es/p/good-molecules/discoloration-correcting-serum/for/dry-skin) — High fit — [€26.00 at Amazon](https://www.amazon.de/dp/B08RJ4ZHXJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Acid Serum](https://lovi.care/skincare/es/p/good-molecules/hyaluronic-acid-serum/for/dry-skin) — Superior fit — [€16.68 at Amazon](https://www.amazon.de/dp/B08TM8DLFJ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Gentle Retinol Cream](https://lovi.care/skincare/es/p/good-molecules/gentle-retinol-cream/for/mature-skin) — High fit — [€25.39 at Amazon](https://www.amazon.de/dp/B09BST7MMP?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Niacinamide Serum](https://lovi.care/skincare/es/p/good-molecules/niacinamide-serum/for/oily-skin) — Average fit — [€19.68 at Amazon](https://www.amazon.de/dp/B08R994Q1L?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Niacinamide Brightening Toner](https://lovi.care/skincare/es/p/good-molecules/niacinamide-brightening-toner/for/dry-skin) — High fit
- [PIMPLE PATCHES](https://lovi.care/skincare/es/p/good-molecules/pimple-patches/for/acne-prone-skin) — Average fit
- [Yerba Mate Wake Up Eye Gel](https://lovi.care/skincare/es/p/good-molecules/yerba-mate-wake-up-eye-gel/for/mature-skin) — Superior fit — [€12.33 at Amazon](https://www.amazon.de/dp/B091NJQ29P?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Lightweight Daily Moisturizer](https://lovi.care/skincare/es/p/good-molecules/lightweight-daily-moisturizer/for/dry-skin) — Superior fit — [€28.49 at Amazon](https://www.amazon.de/dp/B0C26KZ7G6?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/es/p/simple/micellar-water/for/mature-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/es/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/es/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [€9.99 at Amazon](https://www.amazon.de/dp/B000LQX6XG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/es/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [€14.98 at Amazon](https://www.amazon.de/dp/B000LQUA6M?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/es/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B014G4ZW1M?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/es/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [€26.26 at Amazon](https://www.amazon.de/dp/B0787G22XC?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/es/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [€9.93 at Amazon](https://www.amazon.de/dp/B076V2D94Y?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## People Say

Good Molecules

Simple

- Gentle on Sensitive Skin Often Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “no skin purging — Good Molecules Gentle Retinol Cream”
- Affordable Price and Great Value Mostly Mentioned Often Mentioned “best value for money — Good Molecules Hyaluronic Acid Serum” “great value — Good Molecules Niacinamide Serum” “great value for money — Simple Kind to Skin Soothing Facial Toner”
- Lightweight and Non-Greasy Texture Mostly Mentioned Often Mentioned “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum” “practically invisible on skin — Good Molecules PIMPLE PATCHES” “absorbs instantly into skin — Good Molecules Lightweight Daily Moisturizer” “sinks in instantly — Simple Water Boost Hydrating Gel Cream”
- Hydration and Plumping Often Mentioned Mostly Mentioned “banished dryness within days — Simple Replenishing Rich Moisturiser” “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water” “Leaves my face feeling soft, not tight. — Simple Micellar Water” “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
- Effective Daily Cleansing Rarely Noted Often Mentioned “Takes off any makeup residue and makes my face feel refreshed. — Simple Micellar Cleansing Water” “Best morning cleanser — Simple Refreshing Facial Wash” “Skin feels soft not dry — Simple Refreshing Facial Wash” “lather on this cleanser is impressive — Good Molecules Hydrating Facial Cleansing Gel”
- Improves Skin Texture and Smoothness Often Mentioned Not noted “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment” “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder” “softened fine lines — Good Molecules Gentle Retinol Cream”
- Insufficient Hydration or Dryness Sometimes Noted Often Mentioned “dried my skin out — Good Molecules Hyaluronic Acid Serum” “not moisturizing enough — Good Molecules Lightweight Daily Moisturizer” “Skin felt tight — Good Molecules Pineapple Exfoliating Powder” “not moisturizing enough — Simple Hydrating Light Moisturiser”
- Caused Breakouts Sometimes Noted Sometimes Noted “face broke out everywhere — Good Molecules Discoloration Correcting Serum” “gave me little white bumps — Good Molecules Niacinamide Serum” “Gave me tiny bumps on my forehead. — Simple Micellar Water” “caused major breakouts — Simple Hydrating Light Moisturiser”
- Texture Issues, Residue, and Soapy Feel Sometimes Noted Sometimes Noted “Feels slimy on skin — Simple Refreshing Facial Wash” “Still feeling a little bit of a film on my skin. — Simple Micellar Cleansing Water” “leaves a tacky film — Simple Kind to Skin Soothing Facial Toner” “sticky to the touch — Good Molecules Niacinamide Brightening Toner”

### Good Molecules vs Simple routines for dry skin

#### Good Molecules-focused routine

- Cleanser: [Hydrating Facial Cleansing Gel](https://lovi.care/skincare/es/p/good-molecules/hydrating-facial-cleansing-gel/for/dry-skin) — High fit — [€28.48 at Amazon](https://www.amazon.de/dp/B0CMGJ1NW4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — [€34.00 at Amazon](https://www.amazon.de/dp/B07P57D5SX?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Lightweight Daily Moisturizer](https://lovi.care/skincare/es/p/good-molecules/lightweight-daily-moisturizer/for/dry-skin) — Superior fit — [€28.49 at Amazon](https://www.amazon.de/dp/B0C26KZ7G6?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/es/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€12.98 at Amazon](https://www.amazon.de/dp/B0CYCBVBTR?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/es/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€10.97 at Amazon](https://www.amazon.de/dp/B084Q16G8D?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Daily Brightening Serum](https://lovi.care/skincare/es/p/good-molecules/daily-brightening-serum/for/dry-skin) — High fit — [€26.02 at Amazon](https://www.amazon.de/dp/B091MGP94B?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Abib Rice Probiotics Overnight Mask](https://lovi.care/skincare/es/p/abib/rice-probiotics-overnight-mask/for/dry-skin) — Superior fit — [€15.30 at Amazon](https://www.amazon.de/dp/B09Z81FRRF?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/es/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [€14.98 at Amazon](https://www.amazon.de/dp/B000LQUA6M?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Advanced Replenishing Toner](https://lovi.care/skincare/es/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — [€34.00 at Amazon](https://www.amazon.de/dp/B07P57D5SX?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/es/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B014G4ZW1M?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/es/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€12.98 at Amazon](https://www.amazon.de/dp/B0CYCBVBTR?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/es/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [SKIN1004 Madagascar Centella Poremizing Fresh Ampoule](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-poremizing-fresh-ampoule/for/dry-skin) — Superior fit — [€14.98 at Amazon](https://www.amazon.de/dp/B0B1JRGGLF?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Abib Rice Probiotics Overnight Mask](https://lovi.care/skincare/es/p/abib/rice-probiotics-overnight-mask/for/dry-skin) — Superior fit — [€15.30 at Amazon](https://www.amazon.de/dp/B09Z81FRRF?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 97% fit](https://lovi.care/skincare/es/skin/dry-skin)

### Good Molecules vs Simple routines for oily skin

#### Good Molecules-focused routine

- Cleanser: [Hydrating Facial Cleansing Gel](https://lovi.care/skincare/es/p/good-molecules/hydrating-facial-cleansing-gel/for/oily-skin) — Average fit — [€28.48 at Amazon](https://www.amazon.de/dp/B0CMGJ1NW4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B07P7VZ2J9?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/es/p/good-molecules/hyaluronic-acid-serum/for/oily-skin) — High fit — [€16.68 at Amazon](https://www.amazon.de/dp/B08TM8DLFJ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/oily-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.de/dp/B091T7JKQJ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [€97.52 at Amazon](https://www.amazon.de/dp/B0DNJRC1L4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/es/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [€16.90 at Amazon](https://www.amazon.de/dp/B0FJ8STLLW?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [€20.99 at Amazon](https://www.amazon.de/dp/B08TMDRF1L?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/es/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/es/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€16.79 at Amazon](https://www.amazon.de/dp/B083X5R6VR?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/es/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [€14.98 at Amazon](https://www.amazon.de/dp/B000LQUA6M?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B07P7VZ2J9?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/es/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B014G4ZW1M?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/es/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/oily-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.de/dp/B091T7JKQJ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/es/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/es/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [€16.90 at Amazon](https://www.amazon.de/dp/B0FJ8STLLW?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/es/p/the-ordinary/niacinamide-10-zinc-1/for/oily-skin) — Superior fit — [€5.20 at Amazon](https://www.amazon.de/dp/B01MDTVZTZ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/es/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/es/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€16.79 at Amazon](https://www.amazon.de/dp/B083X5R6VR?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/es/skin/oily-skin)

### Good Molecules vs Simple routines for combination skin

#### Good Molecules-focused routine

- Cleanser: [Hydrating Facial Cleansing Gel](https://lovi.care/skincare/es/p/good-molecules/hydrating-facial-cleansing-gel/for/combination-skin) — Average fit — [€28.48 at Amazon](https://www.amazon.de/dp/B0CMGJ1NW4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B07P7VZ2J9?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/es/p/good-molecules/hyaluronic-acid-serum/for/combination-skin) — High fit — [€16.68 at Amazon](https://www.amazon.de/dp/B08TM8DLFJ?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/es/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [€97.52 at Amazon](https://www.amazon.de/dp/B0DNJRC1L4?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/es/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.98 at Amazon](https://www.amazon.de/dp/B09V7Z4TJG?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/es/p/good-molecules/overnight-exfoliating-treatment/for/combination-skin) — Superior fit — [€20.99 at Amazon](https://www.amazon.de/dp/B08TMDRF1L?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/es/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/es/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [€28.50 at Amazon](https://www.amazon.de/dp/B0DV8YNCC5?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/es/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [€14.98 at Amazon](https://www.amazon.de/dp/B000LQUA6M?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/es/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.de/dp/B07P7VZ2J9?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/es/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B014G4ZW1M?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/es/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [€9.87 at Amazon](https://www.amazon.de/dp/B00X3OQ6N0?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/es/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.98 at Amazon](https://www.amazon.de/dp/B09V7Z4TJG?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [SKIN1004 Madagascar Centella Spot Cream](https://lovi.care/skincare/es/p/skin1004/madagascar-centella-spot-cream/for/combination-skin) — Superior fit — [€18.49 at Amazon](https://www.amazon.de/dp/B0DHC28K9Y?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/es/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [€48.55 at Amazon](https://www.amazon.de/dp/B0D1YJN279?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Origins Original Skin Retexturizing Mask with Rose Clay](https://lovi.care/skincare/es/p/origins/original-skin-retexturizing-mask-with-rose-clay/for/combination-skin) — Superior fit — [€28.50 at Amazon](https://www.amazon.de/dp/B0DV8YNCC5?tag=lovi-care-web-routine01-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 96% fit](https://lovi.care/skincare/es/skin/combination-skin)

## Questions and answers

### Good Molecules or Simple: which is better?

Good Molecules offers better routine fits across all skin types on this page, including dry, sensitive, and oily skin.

### What is the difference between Good Molecules and Simple?

Good Molecules offers a wider variety of specialized [serums](https://lovi.care/skincare/es/ingredients/serum) and treatments and is rated Superior for dry, oily, combination, sensitive, and acne-prone skin routines, while Simple is known for gentle makeup removers and basic daily cleansers and moisturizers. Reviewers note that Good Molecules is especially praised for affordable serums and smoothing skin texture, whereas Simple is favored for gentle, sensitive-skin-friendly makeup removers.

### Good Molecules or Simple for dry skin?

Good Molecules is a Superior fit for dry skin, whereas Simple is a High fit on this page. Reviewers note that Good Molecules offers affordable and hydrating moisturizers, while the products on this page list no fragrance in their ingredients.

### Good Molecules or Simple: which cleanser is better?

Good Molecules Hydrating Facial Cleansing Gel has a Lovi fit level of High for dry and sensitive skin, whereas Simple Refreshing Facial Wash has a Low fit level for dry skin, making the Good Molecules cleanser a better choice for hydration-focused routines.

### Which is more affordable, Good Molecules or Simple?

Good Molecules is noted for offering affordable price and great value, performing better than Simple in this area across the products on this page.

### Which brand has better products for mature skin, Good Molecules or Simple?

Good Molecules is the better brand for mature skin, as Lovi rates its routine fit as Superior compared to Simple's High. Reviewers frequently note that Good Molecules offers effective and affordable serums that help improve skin texture, while the products on this page list no fragrance.

### Which brand is gentler on sensitive skin, Good Molecules or Simple?

Simple is gentler on sensitive skin compared to Good Molecules. Both brands feature products that contain no fragrance on this page.

### Which brand performs better for hydration and plumping, Good Molecules or Simple?

Simple performs better for hydration and plumping based on reviewer feedback. Topical [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid) helps improve skin quality and hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Good Molecules or Simple for oily skin?

Good Molecules fits oily skin better than Simple, as Lovi rates the routine fit for Good Molecules as Superior compared to High for Simple.

### Good Molecules or Simple: which moisturizer is better?

Good Molecules offers affordable and hydrating moisturizers, while Simple provides lightweight, value-friendly options. Lovi shows that the moisturizers on this page achieve varying fit levels depending on the specific product and skin type.

### Good Molecules or Simple for sensitive skin?

Good Molecules fits sensitive skin better than Simple, as Lovi rates Good Molecules as Superior for sensitive skin while Simple is rated High. Reviewers note that Good Molecules offers very gentle serums, while Simple tends to cause breakouts or irritations.

### Good Molecules or Simple for acne-prone skin?

Good Molecules fits acne-prone skin better, achieving a Superior routine fit compared to Simple's High level. Reviewers mention that Good Molecules offers affordable and great value serums that fade dark spots and improve skin texture.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid, Ascorbic acid powder · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts](https://pubmed.ncbi.nlm.nih.gov/34552134/) Ilex paraguariensis leaf extract · Scientific Reports, 2021
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Anti-acne vulgaris effects of chlorogenic acid by anti-inflammatory activity and lipogenesis inhibition](https://pubmed.ncbi.nlm.nih.gov/33433016/) Ilex paraguariensis leaf extract · Experimental Dermatology, 2021
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Ascorbic acid powder · Journal of Cosmetic Dermatology, 2020
- [A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations](https://pubmed.ncbi.nlm.nih.gov/26119285/) Arbutin · Journal of Cosmetic Dermatology, 2015
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract · Experimental Dermatology, 2015
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2021
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil](https://pubmed.ncbi.nlm.nih.gov/31957954/) Avocado oil · Journal of Cosmetic Dermatology, 2020
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Ilex paraguariensis extract · Frontiers in Chemistry, 2024
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study](https://pubmed.ncbi.nlm.nih.gov/33022197/) Arbutin · Journal of Cosmetic Science, 2020
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract, Camellia sinensis leaf water · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- ['All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation](https://pubmed.ncbi.nlm.nih.gov/34297422/) Acmella oleracea extract · International Journal of Cosmetic Science, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [New topical tranexamic acid derivative for the improvement of hyperpigmentation and inflammation in the sun-damaged skin](https://pubmed.ncbi.nlm.nih.gov/32588531/) Cetyl tranexamate mesylate · Journal of Cosmetic Dermatology, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation](https://pubmed.ncbi.nlm.nih.gov/37183632/) Arbutin · Biomaterials Science, 2023
- [Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres](https://pubmed.ncbi.nlm.nih.gov/25876142/) Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties](https://pubmed.ncbi.nlm.nih.gov/39617635/) Acmella oleracea extract · International Journal of Cosmetic Science, 2025
- [Taurine and Polyphenol Complex Repaired Epidermal Keratinocyte Wounds by Regulating IL8 and TIMP2 Expression](https://pubmed.ncbi.nlm.nih.gov/39194729/) Ilex paraguariensis leaf extract · Current Issues in Molecular Biology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects](https://pubmed.ncbi.nlm.nih.gov/25362595/) Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia oleifera seed oil · Annales Pharmaceutiques Francaises, 2017
- [Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics](https://pubmed.ncbi.nlm.nih.gov/40391588/) Camellia sinensis leaf water · International Journal of Cosmetic Science, 2025
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia oleifera seed oil · International Journal of Cosmetic Science, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Saccharomyces ferment filtrate · Skinmed, 2021
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Camellia sinensis leaf water · Journal of Cosmetic Dermatology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023

## The brands

- American skincare: [Good Molecules](https://lovi.care/skincare/es/brands/good-molecules)
- British skincare: [Simple](https://lovi.care/skincare/es/brands/simple)

## More comparisons

- [SKIN1004 vs Good Molecules](https://lovi.care/skincare/es/compare/skin1004-vs-good-molecules)
- [SKIN1004 vs Simple](https://lovi.care/skincare/es/compare/skin1004-vs-simple)
- [Anua vs Good Molecules](https://lovi.care/skincare/es/compare/anua-vs-good-molecules)
- [Anua vs Simple](https://lovi.care/skincare/es/compare/anua-vs-simple)
- [Medicube vs Good Molecules](https://lovi.care/skincare/es/compare/medicube-vs-good-molecules)
- [Medicube vs Simple](https://lovi.care/skincare/es/compare/medicube-vs-simple)
- [The Ordinary vs Good Molecules](https://lovi.care/skincare/es/compare/the-ordinary-vs-good-molecules)
- [The Ordinary vs Simple](https://lovi.care/skincare/es/compare/the-ordinary-vs-simple)
- [Beauty of Joseon vs Good Molecules](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-good-molecules)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-simple)
- [COSRX vs Good Molecules](https://lovi.care/skincare/es/compare/cosrx-vs-good-molecules)
- [COSRX vs Simple](https://lovi.care/skincare/es/compare/cosrx-vs-simple)
- [CeraVe vs Good Molecules](https://lovi.care/skincare/es/compare/cerave-vs-good-molecules)
- [CeraVe vs Simple](https://lovi.care/skincare/es/compare/cerave-vs-simple)
- [La Roche-Posay vs Good Molecules](https://lovi.care/skincare/es/compare/la-roche-posay-vs-good-molecules)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/es/compare/la-roche-posay-vs-simple)
- [Dr. Althea vs Good Molecules](https://lovi.care/skincare/es/compare/dr-althea-vs-good-molecules)
- [Dr. Althea vs Simple](https://lovi.care/skincare/es/compare/dr-althea-vs-simple)
- [Some By Mi vs Good Molecules](https://lovi.care/skincare/es/compare/some-by-mi-vs-good-molecules)
- [Some By Mi vs Simple](https://lovi.care/skincare/es/compare/some-by-mi-vs-simple)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/good-molecules-vs-simple
- United Kingdom: https://lovi.care/skincare/uk/compare/good-molecules-vs-simple
- Ireland: https://lovi.care/skincare/ie/compare/good-molecules-vs-simple
- Germany: https://lovi.care/skincare/de/compare/good-molecules-vs-simple
- France: https://lovi.care/skincare/fr/compare/good-molecules-vs-simple
- Italy: https://lovi.care/skincare/it/compare/good-molecules-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/good-molecules-vs-simple
- Spain: https://lovi.care/skincare/es/compare/good-molecules-vs-simple (this page)
- Canada: https://lovi.care/skincare/ca/compare/good-molecules-vs-simple
- Australia: https://lovi.care/skincare/au/compare/good-molecules-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/good-molecules-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/good-molecules-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/good-molecules-vs-simple