# Clinique vs Skintific

Page: https://lovi.care/skincare/es/compare/clinique-vs-skintific

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Clinique and Skintific are popular skincare brands that offer thoughtful selections of moisturizers and [serums](https://lovi.care/skincare/es/ingredients/serum). The American heritage brand relies on [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/es/ingredients/glycerin), and [caffeine](https://lovi.care/skincare/es/ingredients/caffeine) to comfortably balance dry sensitive skin and oily skin, while the other brand features effective formulas that suit all skin types best. Both provide targeted solutions for concerns such as acne, dark spots, and mature skin. Ultimately, the former distinguishes itself through clinically backed barrier restoration and anti-aging benefits, whereas the latter focuses on versatile everyday protection.

Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..

[en.wikipedia.org](https://en.wikipedia.org/wiki/Clinique) [elcompanies.com](https://www.elcompanies.com/en/who-we-are/our-heritage) [businesswire.com](https://www.businesswire.com/news/home/20261019083802/en/The-Este-Lauder-Companies-Appoints-Krista-Lee-Berger-Senior-Vice-President-Global-Marketing-Clinique) [glossy.co](https://www.glossy.co/beauty/glossy-pop-newsletter-clinique-launches-first-ever-creator-led-campaign/)

This page compares some of the most popular Clinique and Skintific products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg905dd21a8f).

### Popular Clinique vs Skintific products

#### Skintific

- [5X Ceramide Barrier Moisture Gel](https://lovi.care/skincare/es/p/skintific/5x-ceramide-barrier-moisture-gel/for/dry-sensitive-skin) — High fit
- [MUGWORT](https://lovi.care/skincare/es/p/skintific/mugwort/for/dry-skin) — Average fit
- [All Day Light Sunscreen Mist](https://lovi.care/skincare/es/p/skintific/all-day-light-sunscreen-mist/for/dark-spots) — High fit
- [AHA BHA PHA LHA Peeling Solution](https://lovi.care/skincare/es/p/skintific/aha-bha-pha-lha-peeling-solution/for/oily-acne-prone-skin) — High fit
- [MATE FIT](https://lovi.care/skincare/es/p/skintific/mate-fit/for/oily-acne-prone-skin) — High fit

#### Clinique

- [moisture surge](https://lovi.care/skincare/es/p/clinique/moisture-surge/for/sensitive-skin) — High fit
- [Take The Day Off Cleansing Balm](https://lovi.care/skincare/es/p/clinique/take-the-day-off-cleansing-balm/for/dry-skin) — Average fit — [€22.53 at Amazon](https://www.amazon.de/dp/B07D5C86RX?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Lotion+](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-lotion/for/dry-skin) — Average fit — [€20.97 at Amazon](https://www.amazon.de/dp/B00CVZ3NJ2?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [All About Eyes](https://lovi.care/skincare/es/p/clinique/all-about-eyes/for/dry-skin) — High fit — [€46.89 at Amazon](https://www.amazon.de/dp/B001IZ0ZFQ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Dramatically Different Moisturizing Gel](https://lovi.care/skincare/es/p/clinique/dramatically-different-moisturizing-gel/for/oily-skin) — High fit — [€24.46 at Amazon](https://www.amazon.de/dp/B003JRI3OG?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/es/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [€71.30 at Lookfantastic](https://www.lookfantastic.es/p/clinique-smart-clinical-repair-wrinkle-correcting-serum-various-sizes/13279421/)
- [Moisture Surge Overnight Mask](https://lovi.care/skincare/es/p/clinique/moisture-surge-overnight-mask/for/dry-skin) — High fit — [€24.50 at Amazon](https://www.amazon.de/dp/B00HSZRQQQ?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- [Clarifying Lotion 2](https://lovi.care/skincare/es/p/clinique/clarifying-lotion-2/for/oily-acne-prone-skin) — Average fit — [€34.39 at Amazon](https://www.amazon.de/dp/B01N184QGF?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)

## People Say

Clinique

Skintific

- Lightweight and fast-absorbing texture Often Mentioned Mostly Mentioned “absorbs instantly — Skintific 5X Ceramide Barrier Moisture Gel” “super light and leaves a radiant glow — Skintific All Day Light Sunscreen Mist” “light as air — Skintific MATE FIT” “sinks in immediately — Clinique moisture surge”
- Sensitive skin care and gentle formula Mostly Mentioned Often Mentioned “never irritated my eyes — Clinique All About Eyes” “No strong scent — Clinique Take The Day Off Cleansing Balm” “No stinging eyes — Clinique Take The Day Off Cleansing Balm” “redness berkurang — Skintific 5X Ceramide Barrier Moisture Gel”
- Good makeup base Often Mentioned Sometimes Noted “foundation glides on — Clinique moisture surge” “holds concealer in place — Clinique All About Eyes” “perfect primer base — Clinique Dramatically Different Moisturizing Gel” “maintain your makeup without any mess — Skintific All Day Light Sunscreen Mist”
- Hydration and plumping effects Often Mentioned Not noted “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+” “skin feels soft and smooth — Clinique Moisture Surge Overnight Mask” “glass skin look — Clinique moisture surge”
- Luxurious texture and feel Sometimes Noted Sometimes Noted “absorbs quickly — Clinique Moisture Surge Overnight Mask” “Skin feels squeaky clean — Clinique Clarifying Lotion 2” “Kulit terasa lebih halus — Skintific AHA BHA PHA LHA Peeling Solution” “Tampak lebih cerah — Skintific AHA BHA PHA LHA Peeling Solution”
- Controls oil and shine Rarely Noted Often Mentioned “controls shine for 8 hours — Skintific MATE FIT” “oil control is good — Skintific 5X Ceramide Barrier Moisture Gel” “keeps me matte — Clinique Dramatically Different Moisturizing Gel”
- Insufficient hydration or dryness Often Mentioned Often Mentioned “skin felt tight — Clinique Dramatically Different Moisturizing Gel” “Made my skin super dry — Clinique Clarifying Lotion 2” “kurang lembab — Skintific 5X Ceramide Barrier Moisture Gel” “cracks if not hydrated — Skintific MATE FIT”
- High price and value issues Often Mentioned Sometimes Noted “isinya sedikit — Skintific 5X Ceramide Barrier Moisture Gel” “runs out very quickly — Skintific All Day Light Sunscreen Mist” “jar is too small for the cost — Clinique moisture surge”
- Unpleasant or strong scent Sometimes Noted Often Mentioned “Smells like nail polish remover — Clinique Clarifying Lotion 2” “Smells like old oil — Clinique Take The Day Off Cleansing Balm” “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+” “scent is actually quite strong — Skintific All Day Light Sunscreen Mist”

## Questions and answers

### Clinique or Skintific: which is better?

Clinique is better for sensitive skin care and hydration effects, whereas Skintific does better at controlling oil and shine with lightweight textures. Reviewers note that Clinique helps provide gentle and effective cleansers, while Skintific tends to have high price and value issues.

### What is the difference between Clinique and Skintific?

Clinique is better for sensitive skin care, hydration, and makeup bases, whereas Skintific excels at lightweight textures and controlling oil and shine. Reviewers mention that Clinique has a higher price point, while Skintific faces some value issues.

### Clinique or Skintific: which moisturizer is better?

Clinique provides hydrating moisturizers like the Smart Clinical Repair Lifting Face + Neck Cream that Lovi rates as High or Superior for dry and mature skin, while Skintific offers the 5X Ceramide Barrier Moisture Gel which Lovi rates as High for dry and dry sensitive skin. Reviewers note that Clinique excels in hydration and plumping effects, whereas Skintific is praised for its lightweight and fast-absorbing texture.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Clinique or Skintific?

Skintific is more affordable, as reviews for the products on this page note high price and value issues with Clinique.

### Which causes fewer breakouts, Clinique or Skintific?

Reviewers note that Clinique sometimes causes breakouts, while there is no reviewer data on breakouts for Skintific.

### Which brand has been established longer, Clinique or Skintific?

Clinique has been established longer, having been founded in 1968 in the United States, whereas Skintific was founded in 2021.

### Do any products from Clinique or Skintific contain fragrance?

Every product on the Clinique page and the Skintific page lists no fragrance in its ingredients.

### Which brand offers products with a Superior Lovi fit level for mature skin?

Clinique offers products with a Superior Lovi fit level for mature skin, specifically with the Smart Clinical Repair Lifting Face + Neck Cream.

## Research behind their key ingredients

- [Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology](https://pubmed.ncbi.nlm.nih.gov/19169201/) Squalene · Molecules, 2009
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Micro-acid complex · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Protecting skin photoaging by NF-kappaB inhibitor](https://pubmed.ncbi.nlm.nih.gov/20540695/) Magnolia officinalis bark extract · Current Drug Metabolism, 2010
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy](https://pubmed.ncbi.nlm.nih.gov/39458583/) Centella asiatica extract · Pharmaceutics, 2024
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf water, Aloe barbadensis · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np, Ceramide eop · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/36350527/) Micro-acid complex · Dermatology and Therapy, 2023
- [Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy](https://pubmed.ncbi.nlm.nih.gov/36985709/) Polygonum cuspidatum root extract · Molecules, 2023
- [Role of Resveratrol in Regulating Cutaneous Functions](https://pubmed.ncbi.nlm.nih.gov/32382280/) Polygonum cuspidatum root extract · Evidence-based Complementary and Alternative Medicine, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Magnolia ovovata extract and its active component magnolol prevent skin photoaging via inhibition of nuclear factor kappaB](https://pubmed.ncbi.nlm.nih.gov/17346696/) Magnolia officinalis bark extract · European Journal of Pharmacology, 2007
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results](https://pubmed.ncbi.nlm.nih.gov/39810881/) Probiotic technology · Journal of Experimental Pharmacology, 2025
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract · Molecules, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida ferment filtrate, Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel extract · Journal of Cosmetic Science, 2018
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Dimethoxytolyl propylresorcinol · Journal of Cosmetic Dermatology, 2021
- [Synergistic action of a triple peptide complex on an essential extra-cellular matrix protein exhibits significant anti-aging benefits](https://pubmed.ncbi.nlm.nih.gov/20618556/) Multi-peptides · Journal of Cosmetic Dermatology, 2010
- [Algae extract protection effect on oxidized protein level in human stratum corneum](https://pubmed.ncbi.nlm.nih.gov/15247018/) Algae extract · Annals of the New York Academy of Sciences, 2004
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Lactobionic acid · Journal of Cosmetic Dermatology, 2010
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Amended safety assessment of Sesamum indicum (sesame) seed oil, hydrogenated sesame seed oil, Sesamum indicum (sesame) oil unsaponifiables, and sodium sesameseedate](https://pubmed.ncbi.nlm.nih.gov/21772026/) Sesamum indicum oil · International Journal of Toxicology, 2011
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study](https://pubmed.ncbi.nlm.nih.gov/30859734/) Lactobionic acid · Journal of Cosmetic Dermatology, 2019
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride, Capric triglyceride · Life, 2023
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome](https://pubmed.ncbi.nlm.nih.gov/37767337/) Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Impact of Hydrocolloid Dressing and Moisturizing Cream as Facial Skin Protectants Among Health Care Workers](https://pubmed.ncbi.nlm.nih.gov/38771104/) Dimethicone · Military Medicine, 2024
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate · Archives of Dermatological Research, 2024
- [The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies](https://pubmed.ncbi.nlm.nih.gov/41668671/) Laminaria digitata extract · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Shea butter · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients](https://pubmed.ncbi.nlm.nih.gov/42698229/) Lactobacillus ferment · International Journal of Cosmetic Science, 2026
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025

## The brands

- American skincare: [Clinique](https://lovi.care/skincare/es/brands/clinique)
- Skincare: [Skintific](https://lovi.care/skincare/es/brands/skintific)

## More comparisons

- [SKIN1004 vs Clinique](https://lovi.care/skincare/es/compare/skin1004-vs-clinique)
- [SKIN1004 vs Skintific](https://lovi.care/skincare/es/compare/skin1004-vs-skintific)
- [Anua vs Clinique](https://lovi.care/skincare/es/compare/anua-vs-clinique)
- [Anua vs Skintific](https://lovi.care/skincare/es/compare/anua-vs-skintific)
- [Medicube vs Clinique](https://lovi.care/skincare/es/compare/medicube-vs-clinique)
- [Medicube vs Skintific](https://lovi.care/skincare/es/compare/medicube-vs-skintific)
- [The Ordinary vs Clinique](https://lovi.care/skincare/es/compare/the-ordinary-vs-clinique)
- [The Ordinary vs Skintific](https://lovi.care/skincare/es/compare/the-ordinary-vs-skintific)
- [Beauty of Joseon vs Clinique](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-clinique)
- [Beauty of Joseon vs Skintific](https://lovi.care/skincare/es/compare/beauty-of-joseon-vs-skintific)
- [COSRX vs Clinique](https://lovi.care/skincare/es/compare/cosrx-vs-clinique)
- [COSRX vs Skintific](https://lovi.care/skincare/es/compare/cosrx-vs-skintific)
- [CeraVe vs Clinique](https://lovi.care/skincare/es/compare/cerave-vs-clinique)
- [CeraVe vs Skintific](https://lovi.care/skincare/es/compare/cerave-vs-skintific)
- [La Roche-Posay vs Clinique](https://lovi.care/skincare/es/compare/la-roche-posay-vs-clinique)
- [La Roche-Posay vs Skintific](https://lovi.care/skincare/es/compare/la-roche-posay-vs-skintific)
- [Dr. Althea vs Clinique](https://lovi.care/skincare/es/compare/dr-althea-vs-clinique)
- [Dr. Althea vs Skintific](https://lovi.care/skincare/es/compare/dr-althea-vs-skintific)
- [Some By Mi vs Clinique](https://lovi.care/skincare/es/compare/some-by-mi-vs-clinique)
- [Some By Mi vs Skintific](https://lovi.care/skincare/es/compare/some-by-mi-vs-skintific)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/clinique-vs-skintific
- United Kingdom: https://lovi.care/skincare/uk/compare/clinique-vs-skintific
- Ireland: https://lovi.care/skincare/ie/compare/clinique-vs-skintific
- Germany: https://lovi.care/skincare/de/compare/clinique-vs-skintific
- France: https://lovi.care/skincare/fr/compare/clinique-vs-skintific
- Italy: https://lovi.care/skincare/it/compare/clinique-vs-skintific
- Netherlands: https://lovi.care/skincare/nl/compare/clinique-vs-skintific
- Spain: https://lovi.care/skincare/es/compare/clinique-vs-skintific (this page)
- Canada: https://lovi.care/skincare/ca/compare/clinique-vs-skintific
- Australia: https://lovi.care/skincare/au/compare/clinique-vs-skintific
- Singapore: https://lovi.care/skincare/sg/compare/clinique-vs-skintific
- Saudi Arabia: https://lovi.care/skincare/sa/compare/clinique-vs-skintific
- United Arab Emirates: https://lovi.care/skincare/ae/compare/clinique-vs-skintific