# Prequel skincare

Page: https://lovi.care/skincare/es/brands/prequel

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Prequel is an American skincare brand founded in 2023 and owned by The Center Brands LLC.

[prnewswire.com](https://www.prnewswire.com/news-releases/dr-samantha-ellis-launches-solution-focused-skincare-brand-prequel-301885229.html) [happi.com](https://www.happi.com/breaking-news/prequel-makes-key-appointments-to-accelerate-next-growth-phase/)

Prequel is loved for its thoughtful cleansers and moisturizers, which rely on carefully measured formulas. Its products suit dry, sensitive, and compromised skin best because the nourishing ingredients support optimal barrier function. The standout products for particular concerns include the [UREA](https://lovi.care/skincare/es/ingredients/urea) ADVANCED RELIEF MOISTURIZING MILK for acne-prone skin, the Barrier Therapy Skin Protectant Cream for skin with dark spots, and the GLEANSER for mature skin. These gentle preparations work together to calm irritation, lock in lasting moisture, and gently cleanse without disrupting the delicate skin surface.

This page covers some of the most popular Prequel products; for the whole Prequel range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pg10b89529b2).

### Other Prequel products

#### Other products

- [GLEANSER](https://lovi.care/skincare/es/p/prequel/gleanser/for/dry-skin) — High fit
- [GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY](https://lovi.care/skincare/es/p/prequel/gleanser-non-drying-glycerin-cleanser-for-face-and-body/for/dry-skin) — High fit
- [UREA ADVANCED RELIEF MOISTURIZING MILK](https://lovi.care/skincare/es/p/prequel/urea-advanced-relief-moisturizing-milk/for/dry-skin) — High fit

## People Say

★4.6

Overall rating based on 3.1k+ reviews

Reviewers most often praise Prequel for excellent value, deep hydration, and smooth skin texture. The most common complaints are difficulty rinsing and breakouts or irritation.

### Highlights

- Great value Mostly Mentioned “massive by face-wash standards — GLEANSER” “huge product — UREA ADVANCED RELIEF MOISTURIZING MILK” “tube is huge — Barrier Therapy Skin Protectant Cream”
- Hydrating cleansers Mostly Mentioned “skin felt like I'd applied a very light moisturizer — GLEANSER” “skin feels moisturized — GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY”
- Soothing cleansers Mostly Mentioned “calmed my redness — GLEANSER” “no stinging — GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY”
- Luxurious cleansers Mostly Mentioned “bouncy and a little viscous — GLEANSER” “thick jelly consistency — GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY”
- Packaging issues Often Mentioned “leaking from the top — UREA ADVANCED RELIEF MOISTURIZING MILK” “pump doesn't lock — GLEANSER” “pump arrived broken — GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY”

Sources: lovi.care, target.com, prequelskin.com, reddit.com, nymag.com, newbeauty.com, and more

## Questions and answers

### Is Prequel worth it?

Yes, Prequel offers great value, and reviewers mostly mention that its cleansers are hydrating, soothing, and luxurious. Lovi rates the Prequel-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin.

### What are Prequel's best products?

Barrier Therapy Skin Protectant Cream is Prequel's best product, as Lovi rates it Superior for both dry and sensitive skin. Reviewers also mention that Prequel offers great value and hydrating cleansers.

### Which Prequel moisturizer is best for dry skin?

Prequel offers [UREA](https://lovi.care/skincare/es/ingredients/urea) ADVANCED RELIEF MOISTURIZING MILK for dry skin. Lovi rates this moisturizer High for dry skin, making it the top choice among the moisturizers on this page for this skin type.

### Does Prequel cause breakouts?

Prequel is unlikely to cause breakouts, and Lovi rates the Prequel-focused routine Superior for acne-prone skin. The Prequel products on this page list no fragrance in their ingredients.

### Is Prequel fragrance-free?

Yes, every one of the Prequel products on this page lists no fragrance in its ingredients. Reviewers often mention that the cleansers are hydrating and soothing.

### What are the key ingredients in Prequel products?

Prequel products feature key ingredients like [glycerin](https://lovi.care/skincare/es/ingredients/glycerin), [niacinamide](https://lovi.care/skincare/es/ingredients/niacinamide), and multi-ceramides that help keep skin hydrated and support the protective barrier. Glycerin helps maintain soft and smooth skin by attracting moisture, while niacinamide helps improve uneven skin tone and texture.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### How do I build a Prequel skincare routine?

To build a Prequel skincare routine, start by washing with GLEANSER or GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY, then smooth on UREA ADVANCED RELIEF MOISTURIZING MILK, and finish with Barrier Therapy Skin Protectant Cream. Lovi rates Prequel-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin.

### What are good alternatives to Prequel?

Good alternatives to Prequel with pages on Lovi include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. Lovi rates Prequel-focused routines as Superior for dry, oily, sensitive, combination, and acne-prone skin.

### Prequel vs CeraVe: which is better?

Prequel offers a better fit for dry skin, where Lovi rates the Prequel-focused routine Superior and the CeraVe-focused routine High. For oily, sensitive, combination, and acne-prone skin, Lovi rates the Prequel-focused routine Superior and the CeraVe-focused routine Superior as well.

### Who owns Prequel, and where is it from?

Prequel is an American brand founded in 2023, owned by The Center Brands LLC.

[prnewswire.com](https://www.prnewswire.com/news-releases/dr-samantha-ellis-launches-solution-focused-skincare-brand-prequel-301885229.html) [happi.com](https://www.happi.com/breaking-news/prequel-makes-key-appointments-to-accelerate-next-growth-phase/)

### Is Prequel cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Prequel as cruelty-free.

### Which Prequel cleanser is best for oily skin?

GLEANSER is the best choice for oily skin among the options on this page, followed by GLEANSER NON-DRYING GLYCERIN CLEANSER FOR FACE AND BODY. Lovi rates both options Average for oily skin.

## Research behind Prequel's key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Multi-ceramides · Scientific Reports, 2022
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Efficacy of ceramides and niacinamide-containing moisturizer versus hydrophilic cream in combination with topical anti-acne treatment in mild to moderate acne vulgaris: A split face, double-blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/38299457/) Multi-ceramides · Journal of Cosmetic Dermatology, 2024
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025

## Similar brands

- American skincare: [CeraVe](https://lovi.care/skincare/es/brands/cerave)
- American skincare: [Cetaphil](https://lovi.care/skincare/es/brands/cetaphil)
- American skincare: [Paula's Choice](https://lovi.care/skincare/es/brands/paula-s-choice)
- American skincare: [Neutrogena](https://lovi.care/skincare/es/brands/neutrogena)
- American skincare: [Kiehl's](https://lovi.care/skincare/es/brands/kiehl-s)
- American skincare: [Dermalogica](https://lovi.care/skincare/es/brands/dermalogica)
- American skincare: [Good Molecules](https://lovi.care/skincare/es/brands/good-molecules)
- American skincare: [Clinique](https://lovi.care/skincare/es/brands/clinique)
- American skincare: [SkinCeuticals](https://lovi.care/skincare/es/brands/skinceuticals)
- American skincare: [Estée Lauder](https://lovi.care/skincare/es/brands/estee-lauder)

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- French skincare: [Caudalie](https://lovi.care/skincare/es/brands/caudalie)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/brands/prequel
- United Kingdom: https://lovi.care/skincare/uk/brands/prequel
- Ireland: https://lovi.care/skincare/ie/brands/prequel
- Germany: https://lovi.care/skincare/de/brands/prequel
- France: https://lovi.care/skincare/fr/brands/prequel
- Italy: https://lovi.care/skincare/it/brands/prequel
- Netherlands: https://lovi.care/skincare/nl/brands/prequel
- Spain: https://lovi.care/skincare/es/brands/prequel (this page)
- Canada: https://lovi.care/skincare/ca/brands/prequel
- Australia: https://lovi.care/skincare/au/brands/prequel
- Singapore: https://lovi.care/skincare/sg/brands/prequel
- Saudi Arabia: https://lovi.care/skincare/sa/brands/prequel
- United Arab Emirates: https://lovi.care/skincare/ae/brands/prequel