# Biossance skincare

Page: https://lovi.care/skincare/es/brands/biossance

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Spain.

Biossance is an American skincare brand founded in 2015 and owned by THG plc since 2023.

[beautymatter.com](https://beautymatter.com/articles/biossance-and-three-other-amyris-brands-find-buyers) [prnewswire.com](https://www.prnewswire.com/news-releases/amyris-officially-launches-biossance-its-consumer-beauty-brand-300093363.html)

Biossance is beloved for its thoughtfully formulated moisturizers, [serums](https://lovi.care/skincare/es/ingredients/serum), eye products, toners, and more, all anchored by nourishing squalane and [glycerin](https://lovi.care/skincare/es/ingredients/glycerin). Its products suit dry sensitive skin and dry skin best, owing to those deeply comforting ingredients. For specific concerns, the standout choices include the Squalane + [Copper Peptide](https://lovi.care/skincare/es/ingredients/copper-peptide) Rapid Plumping Serum for acne-prone skin, the Squalane + [Vitamin C](https://lovi.care/skincare/es/ingredients/vitamin-c) Dark Spot Serum for skin with dark spots, and the Squalane + Vitamin C [Rose Oil](https://lovi.care/skincare/es/ingredients/rose) for mature skin. Together, the brand's key ingredients work harmoniously as squalane increases [collagen](https://lovi.care/skincare/es/ingredients/collagen) and fights oxidative stress, while glycerin boosts hydration and repairs the skin barrier.

[Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

- [Cruelty-free · Leaping Bunny](https://www.leapingbunny.org/brand/biossance-0)
- Squalane
- [Hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid)
- [Glycerin](https://lovi.care/skincare/es/ingredients/glycerin)

This page covers some of the most popular Biossance products; for the whole Biossance range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pg57ea1a3ee0).

### Biossance moisturizers

#### Moisturizers

- [Squalane + Copper Peptide Rapid Plumping Serum](https://lovi.care/skincare/es/p/biossance/squalane-copper-peptide-rapid-plumping-serum/for/dry-skin) — Superior fit — [€47.44 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-copper-peptide-rapid-plumping-serum-50ml/13643574/)
- [Squalane + Vitamin C Rose Oil](https://lovi.care/skincare/es/p/biossance/squalane-vitamin-c-rose-oil/for/mature-skin) — Superior fit — [€50.03 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-vitamin-c-rose-oil-30ml/12766621/)
- [Squalane + Omega Repair Cream](https://lovi.care/skincare/es/p/biossance/squalane-omega-repair-cream/for/dry-skin) — Superior fit — [€58.65 at Lookfantastic](https://www.lookfantastic.es/p/biossance-omega-repair-cream-100ml/14888219/)
- [Squalane + Probiotic Gel Moisturizer](https://lovi.care/skincare/es/p/biossance/squalane-probiotic-gel-moisturizer/for/dry-sensitive-skin) — High fit — [€31.05 at Lookfantastic](https://www.lookfantastic.es/p/biossance-probiotic-bottle-pump-50ml-fs-fg/17625977/)
- [Squalane + Ectoin Overnight Rescue](https://lovi.care/skincare/es/p/biossance/squalane-ectoin-overnight-rescue/for/dry-sensitive-skin) — High fit — [€62.10 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-ectoin-overnight-rescue-50ml/15065083/)

### Other Biossance products

#### Other products

- [Squalane + Amino Aloe Gentle Cleanser](https://lovi.care/skincare/es/p/biossance/squalane-amino-aloe-gentle-cleanser/for/dry-skin) — Superior fit — [€20.70 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-amino-aloe-gentle-cleanser-200ml/13528784/)
- [Squalane + Vitamin C Dark Spot Serum](https://lovi.care/skincare/es/p/biossance/squalane-vitamin-c-dark-spot-serum/for/dark-spots) — Superior fit — [€43.13 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-vitamin-c-dark-spot-serum-30ml/12949004/)
- [Squalane + Phyto-Retinol Serum](https://lovi.care/skincare/es/p/biossance/squalane-phyto-retinol-serum/for/dry-skin) — Superior fit
- [Squalane + Lactic Acid Resurfacing Night Serum](https://lovi.care/skincare/es/p/biossance/squalane-lactic-acid-resurfacing-night-serum/for/sensitive-skin) — Average fit — [€43.13 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-lactic-acid-resurfacing-serum-30ml/12766619/)
- [Squalane + Marine Algae Eye Cream](https://lovi.care/skincare/es/p/biossance/squalane-marine-algae-eye-cream/for/dry-sensitive-skin) — High fit — [€39.68 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-marine-algae-eye-cream-15ml/12766627/)
- [Squalane + Peptide Eye Gel](https://lovi.care/skincare/es/p/biossance/squalane-peptide-eye-gel/for/acne-prone-skin) — High fit
- [Squalane + BHA Pore-Minimizing Toner](https://lovi.care/skincare/es/p/biossance/squalane-bha-pore-minimizing-toner/for/oily-skin) — Superior fit — [€21.56 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-bha-pore-minimising-toner-120ml/13297863/)
- [Squalane + Hyaluronic Toning Mist](https://lovi.care/skincare/es/p/biossance/squalane-hyaluronic-toning-mist/for/dry-skin) — High fit — [€21.56 at Lookfantastic](https://www.lookfantastic.es/p/biossance-squalane-and-hyaluronic-toning-mist-75ml/13222552/)

## People Say

★4.5

Overall rating based on 21.6k+ reviews

Reviewers most often praise Biossance for instant hydration, lightweight textures, and improved skin texture. The most common complaints are high price points and skin irritation or breakouts.

### Highlights

- Deep hydration Mostly Mentioned “floods skin with moisture — Squalane + Copper Peptide Rapid Plumping Serum” “fresh and hydrated — Squalane + Vitamin C Rose Oil” “melts into my skin like butter — Squalane + Omega Repair Cream”
- Lightweight and fast-absorbing moisturizers Mostly Mentioned “lightweight and glides on my face — Squalane + Vitamin C Rose Oil” “absorbs instantly — Squalane + Probiotic Gel Moisturizer” “rich but lightweight — Squalane + Omega Repair Cream”
- Brightening serums Mostly Mentioned “skin looks brighter — Squalane + Vitamin C Dark Spot Serum” “drastically decreased my acne scars — Squalane + Vitamin C Dark Spot Serum” “woke up glowing — Squalane + Lactic Acid Resurfacing Night Serum”
- Soothing and calming properties Often Mentioned “No redness or flaking — Squalane + Phyto-Retinol Serum” “no irritation — Squalane + Marine Algae Eye Cream” “redness vanished overnight — Squalane + Probiotic Gel Moisturizer”
- Improved texture and smoothness Often Mentioned “smooths out rough skin — Squalane + Lactic Acid Resurfacing Night Serum” “absorbs quickly — Squalane + Copper Peptide Rapid Plumping Serum” “skin looks bouncy — Squalane + Copper Peptide Rapid Plumping Serum”
- Excellent makeup base moisturizers Often Mentioned “works perfectly as a makeup base — Squalane + Vitamin C Rose Oil” “makeup sits better — Squalane + Omega Repair Cream” “makeup glides on — Squalane + Probiotic Gel Moisturizer”
- High price point Mostly Mentioned “steep price point — Squalane + Vitamin C Rose Oil” “bit of a splurge — Squalane + Marine Algae Eye Cream” “too expensive — Squalane + Peptide Eye Gel”
- Scent complaints Sometimes Noted “smells like dirty feet — Squalane + Omega Repair Cream” “smells a bit funny — Squalane + Lactic Acid Resurfacing Night Serum” “smell is too strong — Squalane + Vitamin C Rose Oil”
- Causes breakouts and skin irritation Sometimes Noted “caused breakouts — Squalane + Copper Peptide Rapid Plumping Serum” “broke me out very badly — Squalane + Vitamin C Rose Oil” “caused milia — Squalane + Marine Algae Eye Cream”
- Packaging and dropper issues Sometimes Noted “dropper has broken every single time — Squalane + Vitamin C Rose Oil” “comes out too fast — Squalane + BHA Pore-Minimizing Toner” “lid was busted — Squalane + Omega Repair Cream”

Sources: lovi.care, biossance.com, sephora.sg, influenster.com, reddit.com, cultbeauty.co.uk, and more

## Questions and answers

### Is Biossance good for oily skin?

Yes, Biossance is good for oily skin because Lovi rates the Biossance-focused routine High for oily skin. Reviewers note that the brand provides lightweight and fast-absorbing moisturizers, and the Biossance products on this page list no fragrance.

### Is Biossance worth it?

Biossance is worth it for shoppers seeking effective hydration and soothing care, as Lovi rates the brand's routines Superior for dry and sensitive skin. Reviewers widely praise the deep moisture and brightening [serums](https://lovi.care/skincare/es/ingredients/serum), although some note a high price point.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### What are Biossance's best products?

Biossance features several top-performing items, including the Squalane + [Vitamin C](https://lovi.care/skincare/es/ingredients/vitamin-c) Dark Spot Serum, Squalane + [Copper Peptide](https://lovi.care/skincare/es/ingredients/copper-peptide) Rapid Plumping Serum, and Squalane + Vitamin C [Rose Oil](https://lovi.care/skincare/es/ingredients/rose), which Lovi rates Superior for dry skin. Reviewers often mention deep hydration and lightweight moisturizers as key benefits across these selections.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### Which Biossance moisturizer is best for dry skin?

Lovi rates the Squalane + Copper Peptide Rapid Plumping Serum as best for dry skin, followed by the Squalane + Omega Repair Cream and the Squalane + Vitamin C Rose Oil. These moisturizers help deliver deep hydration to keep dry skin feeling soft and smooth.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### Does Biossance cause breakouts?

Reviewers sometimes note that Biossance products may cause breakouts and skin irritation, though the Biossance products on this page list no fragrance in their ingredients.

### Is Biossance fragrance-free?

Yes, the Biossance products on this page list no fragrance in their ingredients. Reviewers note occasional scent complaints, but the brand features no added fragrances across its range.

### What are the key ingredients in Biossance products?

The key ingredients found across the Biossance products on this page include squalane, [hyaluronic acid](https://lovi.care/skincare/es/ingredients/hyaluronic-acid), and [glycerin](https://lovi.care/skincare/es/ingredients/glycerin). Topical use of hyaluronic acid may help improve skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### How do I build a Biossance skincare routine?

To build a Biossance routine for dry skin in the morning, start with the Squalane + Amino Aloe Gentle Cleanser, follow with the Squalane + Hyaluronic Toning Mist, and finish with the Squalane + Copper Peptide Rapid Plumping Serum. The evening routine includes a pre-cleanse with the Squalane + Vitamin C Rose Oil, the cleanser, the Squalane + Vitamin C Dark Spot Serum, and the rapid plumping serum. Once a week, add the [Rice Probiotics](https://lovi.care/skincare/es/ingredients/rice) Overnight Mask after cleansing and before applying the serum and moisturizer.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

### Where can I buy Biossance, and how much does it cost?

Biossance can be purchased in Spain through the Lovi page, where prices range from €20.70 to €62.10, with most items falling between €21.56 and €50.03. Reviewers note that the brand comes with a high price point.

### What are good alternatives to Biossance?

CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica are good alternatives to Biossance because they also offer specialized skincare ranges with similar skin type focuses. Lovi rates these brands across various skin types, showing comparable fit levels.

### Biossance vs CeraVe: which is better?

Lovi rates the Biossance-focused routine Superior for dry skin and sensitive skin, while CeraVe rates Superior for oily, combination, and acne-prone skin. Reviewers note that Biossance products provide deep hydration and brightening serums with a high price point.

### Who owns Biossance, and where is it from?

Biossance is an American brand founded in 2015, owned by THG plc since 2023.

[beautymatter.com](https://beautymatter.com/articles/biossance-and-three-other-amyris-brands-find-buyers) [prnewswire.com](https://www.prnewswire.com/news-releases/amyris-officially-launches-biossance-its-consumer-beauty-brand-300093363.html)

### Is Biossance cruelty-free?

Yes: Leaping Bunny lists Biossance as cruelty-free.

[Leaping Bunny](https://www.leapingbunny.org/brand/biossance-0)

### Is Biossance good for dry skin?

Lovi rates Biossance Superior for dry skin, supported by brand routines and deep hydration favored by reviewers. The Biossance products on this page list no fragrance, and key ingredients like squalane and sodium hyaluronate help provide deep hydration and improve skin quality.

[Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which Biossance cleanser is best for oily skin?

The Biossance cleanser best for oily skin is the Squalane + Amino Aloe Gentle Cleanser, which Lovi rates High for oily skin. Reviewers often note that Biossance products provide deep hydration and leave skin smooth.

### Is Biossance good for sensitive skin?

Lovi rates Biossance Superior for sensitive skin, and the Biossance products on this page list no fragrance in their ingredients. Reviewers often mention its soothing and calming properties.

### Is Biossance good for acne-prone skin?

Yes, Biossance is good for acne-prone skin, as Lovi rates the brand-focused routine High for this skin type. Reviewers often mention that its lightweight moisturizers and serums help improve skin texture and smoothness.

### Is Biossance good for skin with dark spots?

Yes, Biossance is good for skin with dark spots because Lovi rates the brand's dark spot serum and vitamin C rose oil as Superior for this skin type. Reviewers mostly mention that these brightening serums help improve texture and smoothness, while key ingredients like vitamin C help reduce dark spots.

[Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Is Biossance good for mature skin?

Lovi rates Biossance Average for mature skin overall, though individual items like the Squalane + Vitamin C Rose Oil and Squalane + [BHA](https://lovi.care/skincare/es/ingredients/salicylic-acid) Pore-Minimizing Toner reach a Superior fit level. Reviewers mention that the brand helps deliver deep hydration and smooths out skin texture.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/)

## Research behind Biossance's key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation](https://pubmed.ncbi.nlm.nih.gov/17956979/) Lepidium sativum extract sprout · Proceedings of the National Academy of Sciences of the United States of America, 2007
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis · Clinical Pharmacology, 2018
- [Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: role of Nrf2-dependent gene expression and antioxidant enzymes](https://pubmed.ncbi.nlm.nih.gov/24121007/) Lepidium sativum extract sprout · Pharmacological Research, 2013
- [Moringa oleifera Leaf Extracts as Multifunctional Ingredients for "Natural and Organic" Sunscreens and Photoprotective Preparations](https://pubmed.ncbi.nlm.nih.gov/29543741/) Moringa oleifera leaf extract · Molecules, 2018
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Bha beta hydroxy acid · BioMed Research International, 2020
- [A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties](https://pubmed.ncbi.nlm.nih.gov/35200634/) Dunaliella salina extract · Marine Drugs, 2022
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Bha beta hydroxy acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Exploring the antioxidant potentiality of two food by-products into a topical cream: stability, in vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/26393899/) Medicago sativa extract · Drug Development and Industrial Pharmacy, 2016
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Bha beta hydroxy acid · Journal of Drugs in Dermatology, 2023
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Aloe barbadensis flower extract, Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- ['All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation](https://pubmed.ncbi.nlm.nih.gov/34297422/) Acmella oleracea extract · International Journal of Cosmetic Science, 2021
- [Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations](https://pubmed.ncbi.nlm.nih.gov/33561977/) Complex amino acid · International Journal of Molecular Sciences, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [A clinical evaluation of the efficacy and tolerability of a novel topical antioxidant formulation featuring vitamin C, astaxanthin, and fermented turmeric](https://pubmed.ncbi.nlm.nih.gov/37608511/) Astaxanthin · Journal of Cosmetic Dermatology, 2023
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil](https://pubmed.ncbi.nlm.nih.gov/24451077/) Rose oil · Acta Pharmaceutica, 2013
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera leaf extract · Polymers, 2022
- [Hydrolipidic Characteristics and Clinical Efficacy of a Dermocosmetic Formulation for the Improvement of Homeostasis on Oily Mature Skin](https://pubmed.ncbi.nlm.nih.gov/36676036/) Medicago sativa extract · Life, 2022
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Preparation and characterization of astaxanthin-loaded biodegradable polyhydroxybutyrate (PHB) microbeads for personal care and cosmetic applications](https://pubmed.ncbi.nlm.nih.gov/38072340/) Astaxanthin · International Journal of Biological Macromolecules, 2024
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed sodium hyaluronate · Aesthetic Plastic Surgery, 2026
- [Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/35048513/) Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022
- [Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties](https://pubmed.ncbi.nlm.nih.gov/39617635/) Acmella oleracea extract · International Journal of Cosmetic Science, 2025
- [Improvement of urban eye skin in Chinese female by supramolecular retinol plus acmella oleracea extract-containing product](https://pubmed.ncbi.nlm.nih.gov/34806292/) Acmella oleracea extract · Journal of Cosmetic Dermatology, 2022
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study](https://pubmed.ncbi.nlm.nih.gov/19146603/) Jojoba esters · Journal of Cosmetic Dermatology, 2008
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed sodium hyaluronate · Colloids and Surfaces. B, Biointerfaces, 2022
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu](https://pubmed.ncbi.nlm.nih.gov/42573538/) Copper tripeptide-1 · Skin Research and Technology, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## Biossance routines

- 93% fit: [Routine for dry skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/dry-skin)
- 85% fit: [Routine for oily skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/oily-skin)
- 87% fit: [Routine for combination skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/combination-skin)
- 92% fit: [Routine for sensitive skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/sensitive-skin)
- 88% fit: [Routine for acne-prone skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/acne-prone-skin)
- 90% fit: [Routine for mature skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/mature-skin)
- 90% fit: [Routine for skin with dark spots](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/dark-spots)
- 94% fit: [Routine for dry sensitive skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/dry-sensitive-skin)
- 88% fit: [Routine for oily acne-prone skin](https://lovi.care/skincare/es/brands/biossance/skincare-routine/for/oily-acne-prone-skin)

## Similar brands

- American skincare: [CeraVe](https://lovi.care/skincare/es/brands/cerave)
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- American skincare: [Paula's Choice](https://lovi.care/skincare/es/brands/paula-s-choice)
- American skincare: [Neutrogena](https://lovi.care/skincare/es/brands/neutrogena)
- American skincare: [Kiehl's](https://lovi.care/skincare/es/brands/kiehl-s)
- American skincare: [Dermalogica](https://lovi.care/skincare/es/brands/dermalogica)
- American skincare: [Good Molecules](https://lovi.care/skincare/es/brands/good-molecules)
- American skincare: [Clinique](https://lovi.care/skincare/es/brands/clinique)
- American skincare: [SkinCeuticals](https://lovi.care/skincare/es/brands/skinceuticals)
- American skincare: [Estée Lauder](https://lovi.care/skincare/es/brands/estee-lauder)

## Popular brands

- Korean skincare: [SKIN1004](https://lovi.care/skincare/es/brands/skin1004)
- Korean skincare: [Anua](https://lovi.care/skincare/es/brands/anua)
- Korean skincare: [Medicube](https://lovi.care/skincare/es/brands/medicube)
- Canadian skincare: [The Ordinary](https://lovi.care/skincare/es/brands/the-ordinary)
- Korean skincare: [Beauty of Joseon](https://lovi.care/skincare/es/brands/beauty-of-joseon)
- Korean skincare: [COSRX](https://lovi.care/skincare/es/brands/cosrx)
- French skincare: [La Roche-Posay](https://lovi.care/skincare/es/brands/la-roche-posay)
- Korean skincare: [Dr. Althea](https://lovi.care/skincare/es/brands/dr-althea)
- Korean skincare: [Some By Mi](https://lovi.care/skincare/es/brands/some-by-mi)
- Korean skincare: [Torriden](https://lovi.care/skincare/es/brands/torriden)
- Korean skincare: [celimax](https://lovi.care/skincare/es/brands/celimax)
- Korean skincare: [Purito](https://lovi.care/skincare/es/brands/purito)
- Korean skincare: [ROUND LAB](https://lovi.care/skincare/es/brands/round-lab)
- Korean skincare: [AXIS-Y](https://lovi.care/skincare/es/brands/axis-y)
- Korean skincare: [d'Alba](https://lovi.care/skincare/es/brands/d-alba)
- Korean skincare: [LANEIGE](https://lovi.care/skincare/es/brands/laneige)
- Korean skincare: [Haruharu Wonder](https://lovi.care/skincare/es/brands/haruharu-wonder)
- Korean skincare: [Pyunkang Yul](https://lovi.care/skincare/es/brands/pyunkang-yul)
- Korean skincare: [innisfree](https://lovi.care/skincare/es/brands/innisfree)
- French skincare: [Caudalie](https://lovi.care/skincare/es/brands/caudalie)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/brands/biossance
- United Kingdom: https://lovi.care/skincare/uk/brands/biossance
- Ireland: https://lovi.care/skincare/ie/brands/biossance
- Germany: https://lovi.care/skincare/de/brands/biossance
- France: https://lovi.care/skincare/fr/brands/biossance
- Italy: https://lovi.care/skincare/it/brands/biossance
- Netherlands: https://lovi.care/skincare/nl/brands/biossance
- Spain: https://lovi.care/skincare/es/brands/biossance (this page)
- Canada: https://lovi.care/skincare/ca/brands/biossance
- Australia: https://lovi.care/skincare/au/brands/biossance
- Singapore: https://lovi.care/skincare/sg/brands/biossance
- Saudi Arabia: https://lovi.care/skincare/sa/brands/biossance
- United Arab Emirates: https://lovi.care/skincare/ae/brands/biossance