Yes to Tomatoes Acne Clearing Facial Toner for acne-prone skin

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Questions and answers

What the research says

• Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients.

  The Australasian Journal of Dermatology, 1992

• Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods.

  Skin Research and Technology, 2023

• Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris.

  Clinical, Cosmetic and Investigational Dermatology, 2019

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical application of blackberry extract protects SKH-1 mice skin from chronic UVB-induced oxidative damage and inflammation by reducing hyperplasia, inflammatory cell infiltration, oxidative markers, pro-inflammatory cytokines, and modulating MAP kinase and NF-kappaB signaling pathways.

  Toxicology and Applied Pharmacology, 2015

• Topical lycopene-based emulgel significantly enhanced skin hydration and elasticity while reducing erythema, melanin, and sebum contents in human volunteers compared to a placebo formulation over 12 weeks.

  European Journal of Pharmaceutics and Biopharmaceutics, 2022

• Cosmetic formulations containing lycopene and melatonin showed significant differences in skin sebum content, hydration, elasticity, erythema index, and melanin index compared to control in 36 healthy women.

  Skin Pharmacology and Physiology, 2020

• Topical delivery of lycopene via MG- and TG-containing microemulsions significantly increased stratum corneum and viable skin layer penetration compared to a control solution, with the MG-containing microemulsion also increasing skin antioxidant activity by 10-fold.

  Journal of Pharmaceutical Sciences, 2010

• A Hamamelis virginiana leaf extract increased LOXL1 expression twofold, decreased elafin synthesis, restored functional elastic fibers, reduced nonfunctional elastin aggregates, decreased wrinkles, and improved skin firmness.

  Journal of Cosmetic Science, 2018

• Hamamelis bark proanthocyanidins strongly increased the proliferation of cultured human keratinocytes and reduced transepidermal water loss and erythema formation in SLS-irritated skin, whereas the polysaccharide fraction had no effect.

  Phytochemistry, 2001

• Witch hazel bark extract and hamamelitannin showed pronounced anti-inflammatory activity, supported keratinocyte migration in a wound healing assay, and inhibited Staphylococcus aureus growth, whereas their skin microbiota metabolite ellagic acid stimulated inflammatory mediator release.

  Journal of Ethnopharmacology, 2025

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified.

  Skin Research and Technology, 2006

• A blackberry and dill extract combination synergistically increased skin elasticity and induced elastogenesis compared to each ingredient alone and placebo.

  International Journal of Cosmetic Science, 2020

• Tropical highland blackberry juice reduced UVB-mediated DNA damage and increased apoptosis in human epidermal keratinocytes and a reconstituted skin equivalent model.

  Photochemistry and Photobiology, 2013

• Strawberry and blackberry crude extracts, anthocyanin-enriched fractions, and proanthocyanidin-enriched fractions demonstrated anti-inflammatory effects through ROS reduction, gene expression inhibition, and NO suppression, while anthocyanin fractions promoted fibroblast migration in vitro.

  Food Research International, 2019

• Coniferyl alcohol derived from seed watermelon promoted linoleic acid-stimulated lipogenesis by approximately 2.2-fold at 300 µM and increased total lipid content in SZ95 sebocytes compared to controls.

  Molecules, 2025

Ingredients

Water, Sd Alcohol 40-B, Witch Hazel Extract Bark Twig Leaf, Glycerin, Sorbitol, Aloe Barbadensis Leaf Juice, Gluconolactone, Alcohol, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Blackberry Fruit Extract, Watermelon Fruit Extract, Melia Azadirachta Leaf Extract Neem Leaf Extract, Melia Azadirachta Flower Extract Neem Flower Extract, Lens Esculenta Seed Extract, Coccinia Indica Fruit Extract, Corallina Officinalis Extract, Camellia Sinensis Leaf Extract, Amino Esters-1, Betaine, Caramel, Sodium Benzoate, Sodium Hydroxide

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.