# The Ordinary Multi-Peptide + Copper Peptides 1% Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [The Ordinary](https://lovi.care/skincare/de/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers excellent skin firming and plumping for your combination skin due to multiple peptides like Copper Tripeptide-1 and Acetyl Hexapeptide-8, which support skin elasticity and hydration. Glycerin and Sodium Hyaluronate Crosspolymer further enhance humectant action, providing basic hydration suitable for your skin type.
- While the formula provides general skincare benefits and barrier support, it does not directly address your primary concerns of acne, blemishes, and breakouts.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Sodium Hyaluronate, Lactococcus Lysate Ferment

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

A notable number of reviews mention a metallic scent and some users report experiencing irritation or stickiness, particularly those with sensitive skin.

- Liked: Improves firmness (often mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Smooths texture (often mentioned)
- Disliked: Unpleasant scent (often mentioned)
- Liked: Accelerates healing (sometimes noted)
- Liked: Value for money (sometimes noted)
- Disliked: Initial stickiness (sometimes noted)
- Disliked: Product conflicts (sometimes noted)
- Disliked: Pricey for brand (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does The Ordinary Multi-Peptide + Copper Peptides 1% work for acne-prone skin?

The Ordinary Multi-Peptide + Copper Peptides 1% Serum is an average fit for acne-prone skin because it supports hydration and barrier strength, though it does not directly target breakouts. A treatment for this skin needs ingredients like niacinamide, zinc PCA, and propolis to help manage blemishes and control excess oil.

### Which ingredients make this serum a good fit for acne-prone skin?

This serum works for acne-prone skin because it contains glycerin and sodium hyaluronate, which provide basic hydration. However, an acne-prone skin type needs a product with ingredients like niacinamide, propolis, and zinc PCA to target breakouts and control oiliness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Copper Tripeptide-1 do for acne-prone skin?

Copper Tripeptide-1 helps calm acne-prone skin by reducing inflammation and supporting overall skin repair. Because this is a weaker match for your skin, an ideal product of this type needs soothing ingredients and gentle hydrators to calm irritation without clogging pores.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [International Journal of Molecular Sciences, 2018](https://pubmed.ncbi.nlm.nih.gov/29986520/)

### What does Argireline do for acne-prone skin?

Argireline is not typically targeted for acne-prone skin, as it is primarily used to smooth fine lines and reduce wrinkles by relaxing facial movements. While it helps keep skin smooth, acne-prone skin generally needs ingredients that clear pores, calm redness, and balance oil production.

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine, applied after cleansing and before moisturizing. While it is safe for acne-prone skin, a product of this type needs soothing ingredients and blemish-fighting actives to properly target breakouts.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first, letting it absorb, and following with your retinol. This product is safe for your skin with no risks of irritation, though acne-prone skin needs a treatment with active ingredients that clear breakouts and target blemishes.

### How often should I use this serum?

You can use this treatment in your evening routine. Acne-prone skin needs products containing targeted blemish-fighting ingredients and soothing agents to help clear breakouts.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause irritation or breakouts on acne-prone skin, but it does not directly target pimples or blemishes either. Acne-prone skin works best with products that contain targeted blemish-fighting ingredients and oil-balancing components.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €9.99 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.29 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €16.59 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €13.67 at Amazon

## Where to buy

- Amazon.de: €27.95 (https://www.amazon.de/dp/B0C9DXGXZ3?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €33.50 (https://www.notino.de/the-ordinary/multi-peptide-copper-peptides-1-aufhellendes-anti-falten-serum/p-16193594/)
Prices checked 15 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Copper Tripeptide-1, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium Pca, Pca, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Dimethyl Isosorbide, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/acne-prone-skin