# The INKEY List Collagen Peptide Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [The INKEY List](https://lovi.care/skincare/de/brands/the-inkey-list)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent plumping and firming for your combination skin due to acetyl hexapeptide-8 and palmitoyl tripeptide-1, which improve volume and elasticity while glycerin and butylene glycol hydrate without exacerbating oiliness.
- The peptides also provide moderate benefits for acne and blemishes by supporting skin repair and reducing inflammation.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing glycerin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/oily-acne-prone-skin): High

## Key ingredients

Collagen Peptides, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Collagen peptides induced cell proliferation and pro-collagen-1α expression, increased TGF-β and VEGF, and suppressed the LPS-induced inflammatory response in human skin fibroblasts and keratinocytes. ([Nutrients, 2022](https://pubmed.ncbi.nlm.nih.gov/36501011/))
- A liquid formulation containing hydrolyzed collagen demonstrated structural stability, peptide mass distribution between 0.5 and 19.5 kDa, and faded forehead wrinkles in five volunteers while proving to be non-irritating and hypoallergenic. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32390321/))
- Exposure to collagen peptides increased the expression of COL1A1, ELN, and VCAN genes and collagen protein levels in cultured human dermal fibroblasts compared to untreated controls. ([Frontiers in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38751975/))
- Salmo salar and Tilapia nilotica skin collagen peptides accelerate wound healing in a rat murine wound model by reducing proinflammatory cytokines, upregulating BD14, NOD2, IL-10, VEGF, and beta-FGF, and favorably altering wound microflora colonization compared to untreated controls. ([Journal of Agricultural and Food Chemistry, 2020](https://pubmed.ncbi.nlm.nih.gov/31967468/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects. ([Journal of Cosmetic and Laser Therapy, 2013](https://pubmed.ncbi.nlm.nih.gov/23607739/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, this serum is consistently praised for its ability to instantly plump and hydrate the skin, making it appear fresher and smoother. While many appreciate it as an affordable preventative measure for aging, a significant number of reviewers noted that it did not dramatically reduce deep wrinkles or fine lines on its own.

- Liked: Plumps and firms (mostly mentioned)
- Liked: Hydrating (often mentioned)
- Liked: Lightweight & fast-absorbing (often mentioned)
- Liked: Affordable & fragrance-free (sometimes noted)
- Disliked: Lack of dramatic results (sometimes noted)
- Disliked: Messy packaging (sometimes noted)
- Disliked: Runny texture (sometimes noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes The Inkey List Collagen Peptide Serum a great fit for acne-prone skin?

This serum is a great fit because it hydrates without feeling heavy or oily, while peptides help support skin repair and reduce inflammation. It also has a very safe profile with no harsh ingredients, making it unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Which ingredients make this serum a good fit for acne-prone skin?

Glycerin and butylene glycol make this serum a good fit for acne-prone skin because they hydrate without adding oiliness, while peptides help support skin repair and reduce inflammation. It is also unlikely to cause irritation due to the absence of harsh ingredients and the presence of soothing glycerin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Collagen Peptides do for acne-prone skin?

Collagen peptides are unlikely to directly treat acne, but they help improve overall skin hydration and elasticity. To properly care for acne-prone skin, this product needs ingredients that gently clear pores and calm irritation.
Sources: [Nutrients, 2026](https://pubmed.ncbi.nlm.nih.gov/42451143/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### What does Argireline do for acne-prone skin?

Argireline is not typically targeted for acne-prone skin, as it is primarily used to smooth fine lines and reduce wrinkles by relaxing facial movements. While it helps keep skin smooth, acne-prone skin generally needs ingredients that clear pores, calm redness, and balance oil production.

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, which keeps the routine simple and safe around sun exposure. Its ingredients hydrate without increasing oiliness and may help reduce blemishes by calming inflammation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and soothe your skin, followed by your retinol product. This approach helps maintain your skin barrier and is unlikely to cause irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this serum?

This serum is a great fit for your acne-prone skin and is used in the evening routine. Applying it daily helps hydrate without adding oiliness while supporting skin repair.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for acne-prone skin because it hydrates without feeling heavy or oily and has a very safe formula free of harsh ingredients. The peptides it contains may even help reduce inflammation and support skin repair.

### Can I use this serum around the eyes or on my body?

This serum is safe to use around the eyes and on the body because its gentle formula hydrates without clogging pores or causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/de/p/revision-skincare/hydrating-serum/for/acne-prone-skin) — Superior fit — €237.70 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/de/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/acne-prone-skin) — High fit — €37.64 at Amazon
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/de/p/isntree/green-tea-fresh-serum/for/acne-prone-skin) — High fit — €12.56 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €16.59 at Amazon
- SPF: [innisfree Daily UV Defense Mineral Sunscreen](https://lovi.care/skincare/de/p/innisfree/daily-uv-defense-mineral-sunscreen/for/acne-prone-skin) — Superior fit — €65.41 at Amazon

## Where to buy

No store in Germany has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Butylene Glycol, Pentylene Glycol, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carbomer, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Disodium Edta, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/the-inkey-list/collagen-peptide-serum/for/acne-prone-skin