Skinbetter Science AlphaRet Overnight Cream for oily acne-prone skin
Glycolic Acid
Niacinamide
Ethyl Lactyl Retinoate
Sodium Hyaluronate
Squalane
Average
- AverageOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily acne-prone skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your oily skin, as glycolic acid and ethyl lactyl retinoate provide exfoliation and renewal, though it lacks sufficient oil-controlling ingredients for optimal results.
- Glycerin and Bisabolol offer general hydration and soothing benefits, which are supportive but not specifically targeted for your acne, blemishes, and breakouts.
- The formulation is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
People Say
★4.9Overall rating based on 200+ reviewsUsers consistently praise this cream as a "game-changer" for sensitive and aging skin, noting visible improvements in texture, tone, and fine lines without the harsh side effects typical of retinoids. While highly effective for smoothing rough skin and clearing pigmentation, a small minority of users experienced initial purging or found the hydration insufficient for very dry skin types.
Highlights
Gentle & non-irritating Mostly Mentioned
- “No redness or peeling”
- “Great for sensitive skin”
- “Better than tretinoin”
- “Zero irritation”
High price point Mostly Mentioned
- “Very expensive”
- “Hard on the wallet”
- “Pricey investment”
- “Wish it was cheaper”
Effective anti-aging Often Mentioned
- “Softened forehead lines”
- “Skin looks younger”
- “Firmed my skin”
- “Wrinkles are less deep”
Improves texture & tone Often Mentioned
- “Glass skin effect”
- “Smoothed out texture”
- “Faded acne marks”
- “Evened out skin tone”
Hydrating formula Sometimes Noted
- “Feels moisturizing”
- “Creamy texture”
- “Doesn't dry me out”
- “Nice slip”
Packaging design Sometimes Noted
- “Love the twist top”
- “Sanitary pump”
- “Easy to dispense”
- “Protects the product”
Initial purging Rarely Noted
- “Caused bad purging”
- “Broke me out initially”
- “Acne flared up”
- “Tiny bumps appeared”
Not moisturizing enough Rarely Noted
- “Need extra moisturizer”
- “Not enough hydration alone”
- “Still felt dry”
- “Layered with another cream”
Packaging malfunctions Rarely Noted
- “Pump stopped working”
- “Hard to get empty”
- “Can't see how much is left”
- “Broken dispenser”
Sources: lovi.care, skinelite.com, influenster.com, dermstreet.com, realself.com, reddit.com, and more
Questions and answers
How well does AlphaRet Overnight Cream work for oily acne-prone skin?
This cream works moderately well for oily acne-prone skin, as it provides exfoliation and renewal through glycolic acid and ethyl lactyl retinoate, though it lacks sufficient oil-controlling ingredients. While glycerin and bisabolol offer general hydration and soothing benefits, an oily skin type needs a product that specifically controls oil, targets blemishes with acne-fighting ingredients, and delivers lightweight moisture without clogging pores.
Which ingredients make this cream a good fit for oily acne-prone skin?
Glycolic acid and ethyl lactyl retinoate make this cream a fit for your oily skin by providing exfoliation and renewal, while glycerin and bisabolol offer general hydration and soothing benefits. To work best for oily and acne-prone skin, a product of this type needs powerful oil-controlling ingredients, along with hydrating and repairing components that target blemishes and acne without clogging pores or adding excess oil.
What does Glycolic Acid do for oily acne-prone skin?
Glycolic acid helps clear acne-prone skin by reducing pimples and soothing breakouts. It exfoliates the surface to keep pores clear and leaves the skin feeling smooth.
Clinical, Cosmetic and Investigational Dermatology, 2019Dermatologic Surgery, 2014
What does Niacinamide do for oily acne-prone skin?
Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Journal of Cosmetic and Laser Therapy, 2006Journal of Cosmetic Dermatology, 2024
Where does this cream go in a skincare routine for oily acne-prone skin?
This cream goes in the evening routine as a treatment step, applied after cleansing and toning. For this skin, an ideal product of this type needs stronger oil-controlling and targeted blemish-fighting ingredients.
Can I use this cream with retinol, and in what order?
Skinbetter Science AlphaRet Overnight Cream already contains a retinoid, so you should use it on its own at night rather than layering it with another separate retinol product to avoid irritation. Oily acne-prone skin types need a product of this type that also includes targeted oil-controlling ingredients to help manage breakouts.
How often should I use this cream?
You can use this moisturizing treatment in the evening as part of your routine. Start by applying it once a week, and if your skin tolerates it well and you see good results, you may carefully use it more often. Oily acne-prone skin needs products with oil-controlling ingredients to manage breakouts and blemishes.
Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?
This cream is unlikely to clog pores or cause major breakouts for oily acne-prone skin, though mild initial purging may occasionally happen. A product of this type needs stronger oil-controlling ingredients and blemish-targeting components to properly manage this skin.
Can I use this cream around the eyes or on my body?
This cream is safe for the thin skin around the eyes and on the body, but it is better suited for other areas since the eyelids and surrounding regions are much thinner than the back and other body zones. To care for delicate areas like the eyes, a product of this type needs specialized ingredients that address thin-skin concerns without causing irritation.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris.
Clinical, Cosmetic and Investigational Dermatology, 2019A combination of dermapen and glycolic acid peel significantly decreased acne scar grades and resulted in higher patient satisfaction compared to either monotherapy in 30 patients.
Journal of Cosmetic Dermatology, 2019A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks.
International Journal of Dermatology, 2000Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone.
Dermatologic Surgery, 2017Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025
Why other moisturizers fit oily acne-prone skin better
Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.
Molecules, 2023A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels.
Journal of Cosmetic Dermatology, 2017A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide Np, Sodium Hyaluronate, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii Butter Shea Butter, Allantoin Glycyrrhetinic Acid, Sodium Pca, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, Peg-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Tromethamine, Disodium Edta, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide Ci 77891
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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