# SKIN1004 Madagascar Centella Probio-cica Intensive Ampoule for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [SKIN1004](https://lovi.care/skincare/de/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this product leverages Lactobacillus Centella Asiatica Extract Ferment Filtrate and Centella Asiatica Extract to provide anti-inflammatory action and support barrier repair, directly addressing your concerns with acne, blemishes, and breakouts.
- The inclusion of Ceramide NP and Panthenol further enhances barrier resilience and offers soothing benefits, contributing to overall skin health and comfort.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Allantoin, Panthenol

## What the research says

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))

## What reviewers say

This ampoule is widely celebrated for repairing damaged skin barriers and soothing irritation, particularly for dry, sensitive, or mature skin types. Users consistently praise its rich, milky texture that provides deep hydration and a radiant glow without a sticky residue. However, it is often deemed too heavy for oily skin or humid weather. This summary is based on a very large amount of data and should be definitely taken into account.

- Liked: Soothing and calming (mostly mentioned)
- Liked: Deeply moisturizing (often mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Barrier repair (sometimes noted)
- Disliked: Too heavy (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Dropper issues (rarely noted)
- Disliked: Scent concerns (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Probio-cica Intensive Ampoule a great fit for oily acne-prone skin?

This treatment is a great fit for oily acne-prone skin because it uses fermented centella extract and centella extract to calm swelling, clear breakouts, and repair the skin barrier. Ingredients like ceramide NP and panthenol add soothing comfort and help strengthen the skin without causing irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Lactobacillus Centella Asiatica Extract Ferment Filtrate and Centella Asiatica Extract make this serum a great fit by calming inflammation and helping with breakouts on oily skin. Ceramide NP and panthenol also support skin comfort and barrier health without causing irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Lactobacillus do for oily acne-prone skin?

Lactobacillus helps calm oily, acne-prone skin by reducing red spots and balancing oil without harsh side effects. Probiotic treatments of this type may also strengthen the skin barrier while helping to clear up breakouts.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35384257/), [Journal of Experimental Pharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39810881/)

### What does Centella Asiatica Extract do for oily acne-prone skin?

Centella Asiatica Extract helps calm red spots and supports skin healing in oily, acne-prone skin. It may also help balance moisture and reduce breakouts by soothing irritated areas.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. Putting it at night keeps things simple and avoids extra safety concerns around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this treatment with retinol by applying the treatment first to calm your skin and strengthen your barrier, followed by your retinol. This combination helps keep your skin comfortable and smooth while you target breakouts.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this serum?

You can use this treatment in your evening routine. It is very unlikely to irritate oily skin and helps soothe breakouts while supporting your skin barrier.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit for oily acne-prone skin and is unlikely to cause breakouts, as it features soothing ingredients that calm redness and support barrier repair without harsh components. Reviewers rarely mention breakouts, and its safety profile for this skin type is excellent.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — €9.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €29.76 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/de/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — €36.50 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/de/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/oily-acne-prone-skin) — Superior fit — €37.64 at Amazon

## Where to buy

- Amazon.de: €12.50 (https://www.amazon.de/dp/B0F61TFNZM?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Notino: €12.90 (https://www.notino.de/skin1004/madagascar-centella-probio-cica-intensive-ampoule-beruhigendes-serum-regeneriert-die-hautbarriere/p-16210312/)
- Lookfantastic: €22.50 (https://www.lookfantastic.de/p/skin1004-madagascar-centella-probio-cica-intensive-ampoule-50ml/16858551/)
Prices checked 17 Oct – 6 Nov 2026.

## Ingredients

Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Polyhydroxystearic Acid, Betaine, Allantoin, Panthenol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-probio-cica-intensive-ampoule/for/oily-acne-prone-skin