# SKIN1004 Madagascar Centella Asiatica Ampoule for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [SKIN1004](https://lovi.care/skincare/de/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin, the high concentration of Centella Asiatica Extract effectively calms inflammation and aids in skin recovery, directly addressing your acne and blemishes.
- Glycerin further supports your skin by providing essential hydration, balancing both oily and dry areas without causing irritation.
- The formula is safe for your acne-prone skin, featuring soothing ingredients and avoiding harsh components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Glycerin, Butylene Glycol, 1,2-Hexanediol

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Sensory skin irritation potential of 1,2-alkanediols increased with alkane chain length, whereas 1,2-hexanediol showed the lowest objective skin irritation potential compared to both shorter and longer chain lengths, and percutaneous absorption negatively correlated with alkane chain length. ([International Journal of Cosmetic Science, 2011](https://pubmed.ncbi.nlm.nih.gov/21585401/))

## What reviewers say

Based on a very large amount of data, users describe this ampoule as a gentle, watery product that effectively calms redness and repairs the moisture barrier without feeling heavy. It is highly praised by individuals with sensitive, acne-prone, or irritated skin. Some users with resilient skin types find it too lightweight for significant hydration or notice minimal changes.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Soothes redness (mostly mentioned)
- Liked: Safe for sensitive skin (often mentioned)
- Liked: Hydrating for oily skin (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Not hydrating enough (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Madagascar Centella Asiatica Ampoule a great fit for acne-prone skin?

This product is a great fit because the high concentration of Centella Asiatica Extract helps calm inflammation and supports skin recovery. Glycerin adds hydration without irritation, balancing oily and dry areas while the formula avoids harsh components.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this serum a good fit for acne-prone skin?

Centella Asiatica Extract and glycerin make this serum a great fit because they help calm inflammation, support skin recovery, and provide balanced hydration without causing irritation. The formula is very safe for acne-prone skin as it relies on soothing ingredients while avoiding harsh components.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in your evening routine, applied after your cleansing toner and before your moisturizer. Putting it in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the serum first to calm your skin and provide hydration, followed by your retinol. This soothing routine helps balance your skin and may reduce the irritation often caused by retinol.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this treatment in your evening routine, and some treatments can also be used in the morning or twice a day. It is safe for your acne-prone skin, featuring soothing ingredients that help calm inflammation and aid in skin recovery.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause breakouts or clog pores on acne-prone skin because it features soothing ingredients and avoids harsh components. Glycerin helps provide essential hydration without causing irritation, while Centella Asiatica Extract effectively calms inflammation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €9.99 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.29 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €169.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/de/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — €11.75 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/de/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €16.59 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — €13.67 at Amazon

## Where to buy

- Amazon.de: €13.88 (https://www.amazon.de/dp/B07ZKHPV9Y?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €22.13 (https://www.lookfantastic.de/p/skin1004-madagascar-centella-ampoule-100ml/15555881/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Water, Glycerin, Butylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Cellulose Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin (this page)
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-asiatica-ampoule/for/acne-prone-skin
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