REJURAN Rejuran® Healer Turnover Ampoule for acne-prone skin
C-PdrnAverage
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for acne-prone skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate brightening and tone evening for your combination skin, as arbutin and niacinamide help regulate melanogenesis and seboregulation respectively. Aloe barbadensis leaf juice and calendula officinalis flower extract provide supportive hydration and soothing benefits, though they are not primary treatments for your acne concerns.
- The formulation is generally safe for your combination skin, with bisabolol and calendula officinalis flower extract offering soothing properties and no harsh ingredients present.
- This product provides general skincare benefits that are mostly supportive and irrelevant for your specific acne, blemishes, and breakout concerns.
How to apply
- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.8Overall rating based on 500+ reviewsUsers frequently report achieving a radiant "glass skin" appearance and deep hydration with this ampoule, noting significant improvements in skin texture and plumpness. It is often praised for its effectiveness in repairing damaged skin barriers, soothing redness, and aiding in the healing of acne scars. A small number of users with oily skin have found it to be slightly heavy for daytime application.
Highlights
Hydration and glow Mostly Mentioned
- “leaves my skin glowy and plump”
- “instant boost in hydration”
- “natural inner glow”
- “skin looks luminous”
Absorbs quickly Often Mentioned
- “absorbs instantly without tackiness”
- “soaks right in”
- “lightweight formula”
- “doesn't leave oily residue”
Smoother texture Often Mentioned
- “skin texture felt smoother”
- “softens rough edges”
- “makeup doesn't separate anymore”
- “pores look smaller”
Expensive product Often Mentioned
- “price is steep”
- “hard to justify full price”
- “expensive for 30ml”
- “pricier than similar products”
Calms redness Sometimes Noted
- “post-inflammatory erythema faded”
- “calms inflammation quickly”
- “healed acne marks”
Awkward packaging Sometimes Noted
- “dropper is inconvenient”
- “hard to get the last drops”
- “syringe dispenser is finicky”
- “bottle looks full but isn't”
Minor breakouts Rarely Noted
- “caused minor blemishes”
- “gave me whiteheads”
- “reactive bumps appeared”
- “broke me out slightly”
Slightly sticky Rarely Noted
- “feels a bit sticky”
- “too heavy for summer”
- “slightly viscous and tacky”
- “sticky finish on oily skin”
Sources: lovi.care, oliveyoung.com, rejuranusa.com, gopicky.com, skinsort.com, hwahae.co.kr, and more
Questions and answers
How well does Rejuran Healer Turnover Ampoule work for acne-prone skin?
This treatment works moderately well for acne-prone skin by offering some soothing and brightening benefits, but it does not directly target your breakouts. Acne-prone skin needs products containing niacinamide, propolis, or zinc PCA that provide excellent benefits for blemishes and control oiliness while keeping the skin balanced and calm.
The British Journal of Dermatology, 2002Clinical Pharmacology, 2018
Which ingredients make this serum a good fit for acne-prone skin?
Niacinamide and arbutin help even out skin tone, while aloe juice and calendula extract calm the skin, though this serum lacks targeted blemish treatments. Acne-prone skin needs a treatment with ingredients like niacinamide and propolis or zinc PCA that control oil and soothe breakouts without causing irritation.
What does C-Pdrn do for acne-prone skin?
C-PDRN helps calm irritated skin and supports skin healing, making it a useful addition for skin prone to breakouts. It may assist in repairing the skin barrier and improving overall texture when used consistently in your routine.
Pharmaceutics, 2025Current Pharmaceutical Biotechnology, 2026
Where does this serum go in a skincare routine for acne-prone skin?
This treatment goes in your evening routine, applied after cleansing and before your moisturizer. A product of this type for acne-prone skin needs targeted ingredients like acne-fighting acids or retinoids to properly address breakouts and blemishes.
Can I use this serum with retinol, and in what order?
You can use this treatment alongside retinol by applying the treatment first and following with your retinol. Because this product works as an average fit for your acne-prone skin, an acne product of this type needs targeted ingredients that actively clear breakouts and reduce blemishes.
How often should I use this serum?
Apply this serum in your evening routine, using it once a day or a few times a week. This product needs to target breakouts and blemishes more directly with dedicated ingredients like salicylic acid or benzoyl peroxide to truly help acne-prone skin.
Can this serum clog pores, cause breakouts or purging for acne-prone skin?
This treatment is generally safe for your skin, though minor breakouts are unlikely to happen. Acne-prone skin needs targeted blemish-fighting ingredients and oil-balancing agents rather than general soothing and brightening care.
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (benzyl alcohol).
What the research says
Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.
The British Journal of Dermatology, 2002A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects.
International Journal of Molecular Sciences, 2025Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes.
Molecular Medicine Reports, 2023A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model.
Molecules, 2022
Why other serums fit acne-prone skin better
Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris.
The Journal of Clinical and Aesthetic Dermatology, 2020A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo.
BioMed Research International, 2022
Ingredients
Blackberry Leaf Extract, Glycyrrhiza Glabra Callus Culture Extract Licorice Callus Culture Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract Morus Alba Fruit Extract, Arbutin, Butylene Glycol, Glycerin, Polysorbate 20, Hydrolyzed Dna, Hyaluronic Acid, Carbomer, Xanthan Gum, Adenosine, Tocopheryl Acetate, Niacinamide, Bisabolol, Peg-6, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Benzyl Alcohol, 12-Hexanediol, Dipropylene Glycol, Sodium Chloride, Trehalose, Urea
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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