Perricone MD Rebalancing Elixir for combination skin
Cannabidiol
Mushroom Complex
Cherimoya Fruit Extract
Capryloyl Glycine
Sodium Pca
High
- HighCombination Skin Fit
- HighEffectiveness
- HighSafety
One of the best serums for combination skin.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for combination skin, this formula utilizes ingredients like Sodium PCA and Glycerin for humectant action, alongside Annona Cherimola Fruit Extract to help regulate sebum, though more potent agents could further optimize oil control for your oily shine.
- Capryloyl glycine and sodium bicarbonate are included to mattify and control oil production, offering excellent treatment for oily skin.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.5Overall rating based on 800+ reviewsMost users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.
Highlights
Soothes sensitive skin Mostly Mentioned
- “soothed irritation instantly”
- “no stinging on application”
- “relief was real”
Lightweight hydration Often Mentioned
- “absorbs super quickly”
- “skin feels hydrated not oily”
- “lightweight moisture boost”
- “perfect for oily/combo skin”
Good for layering Sometimes Noted
- “makeup went right over it”
- “great base for serums”
- “didn't pill under moisturizer”
- “compatible with hyaluronic acid”
Improves skin texture Sometimes Noted
- “softening effect overall”
- “skin shines bright”
- “balanced my pH”
- “smooths texture perfectly”
Expensive for results Sometimes Noted
- “doesn't justify the price”
- “very expensive for a toner”
- “expected more for the cost”
- “pricey investment”
Not a miracle worker Rarely Noted
- “didn't do miracles”
- “just okay hydration”
- “didn't see major changes”
- “good but not amazing”
Product availability issues Rarely Noted
- “hard to find stock”
- “range has been discontinued”
- “replaced by new line”
- “out of stock everywhere”
Unpleasant natural scent Rarely Noted
- “organic almost gamey scent”
- “smells like mushrooms”
- “scent lingers slightly”
- “weird natural smell”
Sources: lovi.care, perriconemd.com, macys.com, influenster.com, lookfantastic.com, menstylefashion.com, and more
Questions and answers
What makes Perricone MD Rebalancing Elixir a great fit for combination skin?
Perricone MD Rebalancing Elixir is a great fit for combination skin because it uses sodium PCA and glycerin to keep dry areas soft and hydrated while incorporating capryloyl glycine and fruit extract to help control oil. It is very safe for your skin, with no risk of irritation since it leaves out harsh ingredients.
Which ingredients make this elixir a good fit for combination skin?
Sodium PCA and glycerin help keep your dry areas soft and hydrated, while cherimoya fruit extract, capryloyl glycine, and sodium bicarbonate work to calm and control oil on your shiny zones. This blend is unlikely to cause irritation and is a great match for balancing combination skin.
What does Cannabidiol do for combination skin?
Cannabidiol helps calm combination skin by reducing redness and balancing oil production in areas that need it. It is unlikely to cause irritation and may protect the skin barrier while keeping oily and dry spots comfortable.
The Journal of Clinical Investigation, 2014Archives of Dermatological Research, 2024
What does Mushroom Complex do for combination skin?
Mushroom Complex helps hydrate and calm combination skin while providing antioxidant protection to keep the face smooth and balanced. These mushroom extracts support overall skin health and help maintain a clear, even complexion.
Where does this elixir go in a skincare routine for combination skin?
This elixir goes in the evening routine after cleansing and toning, as treatments are placed in the evening for simplicity and extra safety around sun exposure. It is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients.
Can I use this elixir with retinol, and in what order?
You can use this treatment alongside retinol by applying the elixir before your moisturizer in your evening routine, while keeping retinol for a separate night or step to avoid irritation. This product is unlikely to cause irritation on combination skin because it lacks harsh ingredients, helping to keep your skin calm and balanced.
How often should I use this elixir?
Apply this treatment in your evening routine, using it once daily for best results. It is safe for your combination skin and is unlikely to cause irritation.
Can this elixir clog pores, cause breakouts or purging for combination skin?
This elixir is unlikely to clog pores, cause breakouts, or lead to purging on combination skin. It has a high safety profile with no harsh ingredients, meaning it is very unlikely to cause irritation.
Is this elixir fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Menstrual pads containing sodium bicarbonate caused no clinical signs or subclinical vulvar skin irritant reactions in 50 healthy women after 24 hours of patch testing.
The Journal of Reproductive Medicine, 1991Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants.
Journal of the American Academy of Dermatology, 2024Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline.
Journal of Cosmetic Dermatology, 2023Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections.
Aesthetic Surgery Journal. Open Forum, 2022Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.
Journal of Cosmetic Dermatology, 2021Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.
Dermatology and Therapy, 2023Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.
The Journal of Dermatology, 2022Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days.
Journal of Cosmetic Dermatology, 2021A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins.
Biomaterials Advances, 2026
Ingredients
Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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