# Perricone MD Nutritive Cleanser for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [Perricone MD](https://lovi.care/skincare/de/brands/perricone-md)
Category: [Cleansers](https://lovi.care/skincare/de/best/cleansers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other cleansers fit it better.

## Why this fit

- Offers moderate cleansing for your combination skin due to Sodium Laureth Sulfate and Lauryl Glucoside effectively removing impurities, though these ingredients are not specialized for addressing oily shine.
- Dimethyl MEA DMAE and Thioctic Acid Alpha-Lipoic Acid provide antioxidant benefits, but the formula lacks sufficient humectants or emollients for optimal hydration on your combination skin.
- The product is safe for your combination skin as it contains no harsh or prohibited ingredients, minimizing irritation risks.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/oily-acne-prone-skin): Average

## Key ingredients

Alpha Lipoic Acid, Copper Gluconate, Zinc Gluconate, Dimethyl Mea Dmae, Aha Complex

## What the research says

- Topical 30% P407 gel loaded with ALA cubosomes reduced facial lines, nearly resolved fine lines in the periorbital and upper lip areas, and improved skin color and texture without irritation or peeling in volunteers. ([European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/))
- Application of 5% cubosomal alpha lipoic acid gel twice daily for 6 months significantly improved global aesthetic scores and increased epidermal thickness compared to placebo in 20 aging female faces. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/27873449/))
- Treatment with a cream containing 5% alpha-lipoic acid for 12 weeks reduces skin roughness by an average of 50.8% compared to 40.7% with placebo in women with photoaged facial skin. ([The British Journal of Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14616378/))
- Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes. ([The British Journal of Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10215764/))
- A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41487026/))
- Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/))
- Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers. ([Experimental Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23947673/))
- Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo. ([American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/))
- A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE. ([Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/))
- A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties. ([Die Pharmazie, 2009](https://pubmed.ncbi.nlm.nih.gov/20095140/))

## What reviewers say

Based on a very large amount of data, users frequently praise this gel cleanser for its ability to thoroughly remove makeup and oil without stripping the skin's natural moisture barrier, making it a favorite for those with normal to dry skin. Many report softer, brighter, and more radiant skin after use, though a notable minority of users express dissatisfaction with the product's strong fragrance and the recent packaging change from a glass bottle to a plastic tube.

- Liked: Gentle and non-drying (mostly mentioned)
- Liked: Effective makeup remover (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Eye irritation (rarely noted)
- Disliked: High price point (rarely noted)

## How to apply

- Use this cleanser AM and PM as part of your daily routine. Start 3×/week and build up to daily use if your skin tolerates it well.
- Apply this cleanser as the very first step in your morning routine and right after your pre-cleanser in the evening.
- Gently massage a small amount of cleanser onto your skin using circular motions. Rinse thoroughly with lukewarm water.
- For the best results , apply the cleanser directly onto slightly damp skin to help lift away excess oil.
- Avoid the immediate eye area and do a patch test before your first use to check for any sensitivity.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### How well does Perricone MD Nutritive Cleanser work for combination skin?

Perricone MD Nutritive Cleanser is an average fit for your combination skin because it cleanses away impurities with sodium laureth sulfate and lauryl glucoside while offering antioxidant benefits, but it lacks enough hydrating ingredients for dry zones and specialized ingredients for oily shine. A cleanser for combination skin needs a gentle formula that controls shine and clears the complexion while keeping dry areas balanced with hydrating ingredients, soothing extracts, and oils to support the moisture barrier.
Sources: [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### Which ingredients make this cleanser a good fit for combination skin?

Sodium Laureth Sulfate and Lauryl Glucoside help remove impurities well without causing irritation on combination skin. To be a better fit for this skin type, a product of this type needs ingredients that add moisture and manage oily shine.
Sources: [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### What does Alpha Lipoic Acid do for combination skin?

Alpha-lipoic acid helps smooth out rough patches on combination skin when used consistently over time. Studies show that applying a cream with this ingredient twice a day reduces skin roughness and signs of aging.
Sources: [The British Journal of Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14616378/)

### What does Copper Gluconate do for combination skin?

Copper Gluconate helps balance combination skin by controlling excess oil in shiny areas while keeping dry patches comfortable and calm. It also supports a smooth texture and helps maintain a healthy skin barrier.

### Where does this cleanser go in a skincare routine for combination skin?

You can use this cleanser in both your morning and evening routines. It washes away impurities safely without harsh irritation, but because it lacks heavy hydrators, combination skin needs an added hydrating toner and moisturizer right after.

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser with retinol by applying the cleanser first and following it with your retinol treatment. Because this formula lacks sufficient hydrators for your combination skin, this type of routine needs a moisturizing cream or lotion afterward to keep skin soft and smooth.

### How often should I use this cleanser?

You can use this cleanser daily in the morning and evening as part of your routine to wash away dirt and impurities. Because it provides moderate cleansing without being tailored for oily shine or deep hydration, combination skin of this type needs a cleanser that balances oil and adds moisture.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### Can this cleanser clog pores, cause breakouts or purging for combination skin?

Perricone MD Nutritive Cleanser is unlikely to clog pores or cause breakouts on combination skin because it contains no heavy oils or harsh ingredients that commonly trigger irritation. A cleanser for this skin type needs balancing hydrators and gentle pore-clearing ingredients to keep both oily and dry areas comfortable.
Sources: [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### Can I use this cleanser around the eyes or on my body?

You can use this cleanser on your body and around your eyes, as it is safe and unlikely to cause irritation on these areas. However, because the skin around the eyes is very thin and the skin on the body varies in thickness, this type of cleanser works best when it also includes extra moisture and soothing ingredients to keep those areas soft and smooth.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### Is this cleanser fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for combination skin

- [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.99 at Amazon
- [IS Clinical Cleansing Complex](https://lovi.care/skincare/de/p/is-clinical/cleansing-complex/for/combination-skin) — Superior fit — €58.00 at Amazon
- [Missha Super Aqua Ultra Hyalron Cleansing Foam](https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-cleansing-foam/for/combination-skin) — High fit — €10.99 at Amazon

## Pairs well with

- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €13.67 at Amazon
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/de/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — €104.00 at Amazon

## Where to buy

- Amazon.de: €36.80 (https://www.amazon.de/dp/B084RSMQ45?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €36.80 (https://www.lookfantastic.de/p/perricone-md-high-potency-classics-nutritive-cleanser-177ml/13033753/)
- Notino: €37.50 (https://www.notino.de/perriconemd/high-potency-classics-reinigungsgel-mit-nahrhaften-effekt/p-15949910/)
Prices checked 10 Oct – 3 Nov 2026.

## Ingredients

Water, Sodium Laureth Sulfate, Lauryl Glucoside, Cocamidopropyl Betaine, Ppg-2 Hydroxyethyl Coco Isostearamide, Dimethyl Mea Dmae, Citric Acid, Sodium Chloride, Thioctic Acid Alpha-Lipoic Acid, Disodium Edta, Parfum, Benzophenone-4, Magnesium Aspartate, Zinc Gluconate, Copper Gluconate, Methylchloroisothiazolinone, Methylisothiazolinone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/nutritive-cleanser/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/nutritive-cleanser/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/combination-skin (this page)
- France: https://lovi.care/skincare/fr/p/perricone-md/nutritive-cleanser/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/nutritive-cleanser/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/nutritive-cleanser/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/nutritive-cleanser/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/perricone-md/nutritive-cleanser/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/nutritive-cleanser/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/nutritive-cleanser/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/nutritive-cleanser/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/nutritive-cleanser/for/combination-skin