# numbuzin Vitamin-Niacinamide Concentrated Pad for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [numbuzin](https://lovi.care/skincare/de/brands/numbuzin)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your combination skin, as niacinamide helps regulate oil and glycerin provides hydration, though it lacks more potent ingredients for optimal results across all areas.
- The formulation provides excellent brightening and evening of skin tone due to niacinamide and ascorbic acid, which contribute to a more luminous complexion.
- The product is generally safe for your combination skin, with minimal risks of irritation from alcohol and ascorbic acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Glutathione, Ascorbic Acid, Sodium Hyaluronate, Panthenol

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Vitamin C mesotherapy produced a significant and earlier reduction in gingival pigmentation and higher patient satisfaction compared to topical gel in twenty healthy non-smokers with hyperpigmented gingiva, with both methods reducing the mean area fraction of melanin-forming cells at 6 months without causing pain. ([Clinical Oral Investigations, 2021](https://pubmed.ncbi.nlm.nih.gov/33966113/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, users primarily utilize these pads to target hyperpigmentation, acne scars, and dullness, with many reporting a noticeable "glass skin" glow and smoother texture after consistent use. While effective for brightening, reactions are mixed regarding hydration; oily and combination skin types often find them refreshing, whereas those with dry or highly sensitive skin occasionally report dryness, tingling, or breakouts.

- Liked: Effective brightening (often mentioned)
- Liked: Smoother skin texture (often mentioned)
- Liked: Refreshing and lightweight (sometimes noted)
- Liked: Unique dual-sided pad (sometimes noted)
- Disliked: Packaging leaks (sometimes noted)
- Disliked: Drying for some (rarely noted)
- Disliked: Irritation and breakouts (rarely noted)
- Disliked: Texture dislike (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Numbuzin Vitamin-Niacinamide Concentrated Pad work for combination skin?

This pad offers a moderate fit for your combination skin, helping balance oil and provide hydration, though other products fit it better. To work best for this skin, a treatment of this type needs ingredients like propolis or zinc PCA that deeply balance oiliness and hydration without any risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for combination skin?

Niacinamide helps regulate oil while glycerin provides hydration for your combination skin. To work even better for this skin, a treatment of this type needs more potent ingredients and minerals like zinc PCA to better manage oily shine and balance all areas.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Glutathione do for combination skin?

Glutathione helps brighten sun-exposed areas and reduce dark spots for combination skin, while also improving moisture and smoothness. It is unlikely to cause irritation and maintains a safe profile for regular use.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [International Journal of Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39444151/)

### Where does this treatment go in a skincare routine for combination skin?

This treatment goes in the evening routine after cleansing. To work best for combination skin, this type of product needs stronger ingredients that balance oil and hydrate dry areas more effectively.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first and then the retinol after it sinks in, or by using them on alternating nights to keep your skin calm. Combination skin often needs a product that balances oil in the oily zones while providing deeper hydration and stronger barrier-supporting ingredients for the drier areas.

### How often should I use this treatment?

This treatment works for your combination skin once a week to start, and you may carefully use it more often if you tolerate it well and see good results. To better care for combination skin, a product of this type needs more potent ingredients for optimal results across all areas, along with hydrating and oil-balancing ingredients.

### Can this treatment clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to clog pores or cause breakouts for combination skin, as complaints about irritation and breakouts are low. A product for this skin needs ingredients like niacinamide to help balance oil and glycerin to provide lightweight hydration without heavy oils.

### Is this treatment fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/de/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €9.99 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/de/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.29 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/de/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €333.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — €39.99 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/de/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/combination-skin) — Superior fit — €13.67 at Amazon

## Where to buy

- Lookfantastic: €23.00 (https://www.lookfantastic.de/p/numbuzin-no.5-vitamin-niacinamide-concentrated-pad-x-70/17027867/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Niacinamide, Dipropylene Glycol, Glycerin, Propanediol, Butylene Glycol, Hydroxyethyl Urea, Diethoxyethyl Succinate, Hydroxyacetophenone, Caprylyl Glycol, Polyglyceryl-10 Laurate, Betaine, Panthenol, Ethylhexylglycerin, Gluconolactone, Sodium Polyacrylate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Sodium Citrate, Citric Acid, Maltodextrin, 1,2-Hexanediol, Gardenia Florida Fruit Extract, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ascorbic Acid, Pantolactone, Tocopherol, Capryloyl Salicylic Acid, Tranexamic Acid, Tremella Fuciformis Extract Mushroom Extract, Caprylic Capric Triglyceride, Ascorbyl Glucoside, Ubiquinone, Hydrogenated Lecithin, Magnesium Chloride, Alcohol, Glutathione, Polysorbate 80, Calcium Gluconate, Pyridoxine Hcl, Bht, Yeast Extract, Cyanocobalamin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin (this page)
- France: https://lovi.care/skincare/fr/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/vitamin-niacinamide-concentrated-pad/for/combination-skin
