# numbuzin Pantothenic B5 Active Soothing Cream for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [numbuzin](https://lovi.care/skincare/de/brands/numbuzin)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/de/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Excellent suitability for your dry and sensitive skin due to the presence of panthenol and glycerin, which provide humectant action and barrier repair, complemented by niacinamide for hydrating and smoothing texture.
- The formula offers moderate hydration and soothing benefits, effectively supporting your skin barrier function and reducing irritation with ingredients like Centella Asiatica Extract.
- The safety profile is excellent, with no risks of irritation for your dry and sensitive skin due to the absence of prohibited or harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/oily-acne-prone-skin): High

## Key ingredients

Pantothenic Acid Vitamin B5, Niacinamide, Centella Asiatica Extract, Aloe Barbadensis Flower Extract, Glycerin

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, this lightweight gel-cream is widely celebrated by users with oily and acne-prone skin for its ability to hydrate without clogging pores or leaving a greasy residue. While it effectively soothes redness and controls excess sebum, users with dry or dehydrated skin often find it lacks sufficient moisture, particularly during colder months.

- Liked: Lightweight gel texture (mostly mentioned)
- Liked: Soothing & calming (often mentioned)
- Disliked: Insufficient moisture (often mentioned)
- Liked: Non-comedogenic (sometimes noted)
- Liked: Sebum/oil control (sometimes noted)
- Disliked: Breakouts/Reactions (rarely noted)
- Disliked: Packaging concerns (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Numbuzin Pantothenic B5 Cream a great fit for dry sensitive skin?

Numbuzin Pantothenic B5 Active Soothing Cream is a great fit because it contains panthenol and glycerin to soak up water and repair the skin barrier, while niacinamide and Centella Asiatica extract help smooth texture and calm irritation.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for dry sensitive skin?

This cream is a great fit because panthenol and glycerin draw in moisture and help repair your skin barrier, while niacinamide hydrates and leaves your skin smooth. Centella Asiatica Extract also helps calm your skin and ease irritation.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Pantothenic Acid do for dry sensitive skin?

Pantothenic acid helps dry sensitive skin by locking in moisture, reducing redness, and calming irritation while supporting the skin barrier. It keeps skin soft and smooth by improving hydration and assisting cells to survive under stress.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### Where does this cream go in a skincare routine for dry sensitive skin?

This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. It is unlikely to cause irritation and helps calm dry, sensitive skin while supporting your skin barrier function.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it after your retinol helps calm your skin and keep it comfortable. Ingredients like panthenol and glycerin help maintain your skin barrier, while centella asiatica extract reduces irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this cream?

You can use this cream daily as part of your evening routine to keep your skin calm and hydrated. Applying it regularly helps support your skin barrier and is unlikely to cause irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can this cream clog pores, cause breakouts or purging for dry sensitive skin?

This cream is unlikely to cause breakouts or reactions for your dry sensitive skin because it lacks harsh ingredients and contains soothing components that calm irritation. Reviewers rarely report breakouts with this product.

### Can I use this cream around the eyes or on my body?

You can safely use this moisturizing treatment around your eyes and on your body because its gentle formula has an excellent safety profile for dry sensitive skin. Panthenol and glycerin help deeply hydrate dry areas while soothing ingredients like Centella Asiatica extract may help reduce irritation.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/de/p/the-ordinary/natural-moisturizing-factors-ha/for/dry-sensitive-skin) — Superior fit — €11.50 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/de/p/l-occitane/immortelle-divine-cream/for/dry-sensitive-skin) — Superior fit — €95.00 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/de/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/dry-sensitive-skin) — Superior fit — €13.67 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/de/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €8.85 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/de/p/skin1004/centella-asiatica-toning-toner/for/dry-sensitive-skin) — Superior fit — €19.89 at Amazon
- Moisturizer with Sun Protection: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/de/p/torriden/dive-in-mild-sunscreen/for/dry-sensitive-skin) — Superior fit — €18.00 at Amazon

## Where to buy

- Amazon.de: €19.30 (https://www.amazon.de/dp/B0CXSM1K2F?tag=lovi-care-web-product05-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €24.15 (https://www.lookfantastic.de/p/numbuzin-no.1-pantothenic-b5-active-cream-80ml/17750370/)
Prices checked 14 Oct – 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Niacinamide, Cetyl Ethylhexanoate, Dicaprylyl Carbonate, 1,2-Hexanediol, Pentylene Glycol, Vinyl Dimethicone, Centella Asiatica Extract, Caprylyl Methicone, Erythritol, Panthenol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Dimethiconol, Polymethylsilsesquioxane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Chlorella Vulgaris Extract, Glucose, Tromethamine, Silica, Fructooligosaccharides, Fructose, Sophora Angustifolia Root Extract, Ethylhexylglycerin, Xanthan Gum, Sodium Phytate, Glyceryl Acrylate Acrylic Acid Copolymer, Caprylic Capric Triglyceride, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Hydrogenated Lecithin, Ocimum Sanctum Leaf Extract, Tocopherol, Curcuma Longa Root Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Decyl Glucoside, Corallina Officinalis Extract, Pantothenic Acid, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, Willow Bark Extract, Houttuynia Cordata Extract, Coffea Arabica Seed Extract Coffee Seed Extract, Bergamot Leaf Extract, Pinus Densiflora Leaf Extract, Alpha-Arbutin, Zinc Pca, Argania Spinosa Kernel Oil, Methyl Diisopropyl Propionamide, Sesamum Indicum Seed Oil, Serenoa Serrulata Fruit Extract, Beta-Sitosterol, Glycyrrhiza Glabra Root Extract Licorice Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin (this page)
- France: https://lovi.care/skincare/fr/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/pantothenic-b5-active-soothing-cream/for/dry-sensitive-skin