# numbuzin Goodbye Blemish Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Germany.

Brand: [numbuzin](https://lovi.care/skincare/de/brands/numbuzin)
Category: [Serums and treatments](https://lovi.care/skincare/de/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- This product offers excellent treatment for wrinkles and fine lines for your normal skin, as the combination of Ascorbyl Glucoside, Ascorbic Acid, and 3-O-Ethyl Ascorbic Acid promotes collagen synthesis and provides antioxidant protection. Niacinamide and glycerin further support your skin type by offering humectant action and barrier repair.
- The formula also addresses blemishes with niacinamide and ascorbic acid, contributing to brighter and more even skin tone.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like Chamomilla Recutita Flower Extract and Centella Asiatica Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Hippophae Rhamnoides Extract, Curcuma Longa Root Extract, Centella Asiatica Extract, Ascorbic Acid

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of a sea buckthorn fruit extract formulation significantly reduced skin sebum secretion in 10 healthy human volunteers compared to the control base over an 8-week period. ([Journal of Pharmacy & Bioallied Sciences, 2010](https://pubmed.ncbi.nlm.nih.gov/21814424/))
- Topical emulsions containing Hippophae rhamnoides and Cassia fistula plant extracts significantly reduced skin sebum contents compared to placebo in patients with grade I and grade II acne vulgaris. ([Postepy Dermatologii I Alergologii, 2014](https://pubmed.ncbi.nlm.nih.gov/25254008/))
- Topical application of a 5% Hippophae rhamnoides oil-in-water emulsion significantly improved skin hydration (p=0.0003) and transepidermal water loss (p=0.0087) compared to a placebo base formulation in 13 healthy male subjects over 84 days. ([Pakistan Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25362595/))
- Topical application of curcumin or turmeric treats various skin conditions by leveraging antioxidant, anti-inflammatory, and antimicrobial properties. ([Skin Pharmacology and Physiology, 2023](https://pubmed.ncbi.nlm.nih.gov/38008088/))
- Topical formulations of curcumin target oxidative damage and inflammation to improve wound healing in animal models. ([Drug Discovery Today, 2017](https://pubmed.ncbi.nlm.nih.gov/28711364/))
- A curcumin-loaded spanlastic anti-aging gel utilizing formula F5 incorporated into 2% HPMC E50 demonstrated sustained release action, compatibility, and the ability to penetrate skin layers to a depth of about 112.5 um without signs of irritation. ([Saudi Pharmaceutical Journal, 2024](https://pubmed.ncbi.nlm.nih.gov/38178851/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Users with acne-prone and sensitive skin frequently praise this serum for its lightweight, gel-like texture that effectively soothes inflammation and gradually fades post-acne hyperpigmentation. While the majority report a brighter, more even complexion without irritation, a subset of users notes that visible results require patience and consistent use over several weeks.

- Liked: Lightweight texture (mostly mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Disliked: Slow results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Price vs size (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Numbuzin Goodbye Blemish Serum a great fit for mature skin?

This serum is a great fit for mature skin because its blend of vitamin C ingredients and niacinamide helps smooth out fine lines and brighten your skin tone. It also keeps your skin soft and protected with soothing plant extracts and moisturizers that are very unlikely to cause any irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because a blend of Vitamin C types and niacinamide helps smooth fine lines, boost firmness, and brighten dark spots. Glycerin and soothing plant extracts like Centella asiatica also keep your skin deeply hydrated and calm.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Sea Buckthorn Extract do for mature skin?

Sea buckthorn extract helps mature skin by keeping it hydrated and protecting it from sun damage and wrinkles. It is rich in antioxidants that may help keep your skin looking smooth and youthful over time.
Sources: [Pakistan Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/25362595/), [Oxidative Medicine and Cellular Longevity, 2015](https://pubmed.ncbi.nlm.nih.gov/26448818/)

### Where does this serum go in a skincare routine for mature skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. Using vitamin C and niacinamide helps smooth fine lines and brighten your skin tone over time.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this vitamin C product in the morning and your retinol at night to keep your skin smooth and bright without overloading it. Using them at different times of day helps you avoid any potential irritation while still getting the full anti-aging and blemish-fighting benefits.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### How often should I use this serum?

This serum fits your mature skin very well and is used in the evening routine, as treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure. It helps smooth fine lines and brighten your skin tone with a very low risk of irritation, thanks to soothing ingredients like Centella Asiatica extract.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to cause breakouts, as it has a very low risk and features soothing ingredients like Centella asiatica extract that help keep skin calm. The formula is well-tolerated and gentle, making it a safe choice for your skin type.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citral and limonene).

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/de/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/de/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €169.99 at Amazon
- [La Prairie Skin Caviar Liquid Lift](https://lovi.care/skincare/de/p/la-prairie/skin-caviar-liquid-lift/for/mature-skin) — High fit — €730.48 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/de/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — €39.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/de/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €14.00 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/de/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €51.50 at Amazon

## Where to buy

- Notino: €23.90 (https://www.notino.de/numbuzin/no-5-goodbye-blemish-serum-intensives-revitalisierendes-serum-gegen-die-unvollkommenheiten-der-haut/p-16312715/)
Prices checked 16 Oct 2026.

## Ingredients

Hippophae Rhamnoides Extract, Butylene Glycol, Methyl Gluceth-20, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Lemon Peel Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantifolia Oil, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Centella Asiatica Extract, Ascorbyl Glucoside, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Panthenol, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycereth-26, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Laurate, Carbomer, Allantoin, Tromethamine, Water, Hydrolyzed Jojoba Esters, Disodium Edta, Citral, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/numbuzin/goodbye-blemish-serum/for/mature-skin (this page)
- France: https://lovi.care/skincare/fr/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuzin/goodbye-blemish-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuzin/goodbye-blemish-serum/for/mature-skin